The Ratio of FEV1 to FVC as a Basis for Establishing Chronic Obstructive Pulmonary Disease
Vaz Fragoso CA, Concato J, McAvay G, Van Ness PH, Rochester CL, Yaggi HK, Gill TM. The Ratio of FEV1 to FVC as a Basis for Establishing Chronic Obstructive Pulmonary Disease. American Journal Of Respiratory And Critical Care Medicine 2009, 181: 446-451. PMID: 20019341, PMCID: PMC3159085, DOI: 10.1164/rccm.200909-1366oc.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseFEV1/FVCObstructive pulmonary diseaseRisk of deathRespiratory symptomsPulmonary diseaseAdjusted hazard ratioRatio of FEV1Hazard ratioOdds ratioFVCClinical validityFifth percentileZ-scoreIdentifies personsSymptomsWhite personsDiseaseMeaningful outcomesDeathLambda-muPrevalenceRiskRepresentative sampleHigh threshold