Featured Publications
Amplitude and phase measurements from harmonic analysis may lead to new physiologic insights: lower body negative pressure photoplethysmographic waveforms as an example
Alian A, Shelley K, Wu HT. Amplitude and phase measurements from harmonic analysis may lead to new physiologic insights: lower body negative pressure photoplethysmographic waveforms as an example. Journal Of Clinical Monitoring And Computing 2022, 37: 127-137. PMID: 35896756, DOI: 10.1007/s10877-022-00866-6.Peer-Reviewed Original Research
2014
Impact of lower body negative pressure induced hypovolemia on peripheral venous pressure waveform parameters in healthy volunteers
Alian AA, Galante NJ, Stachenfeld NS, Silverman DG, Shelley KH. Impact of lower body negative pressure induced hypovolemia on peripheral venous pressure waveform parameters in healthy volunteers. Physiological Measurement 2014, 35: 1509-1520. PMID: 24901895, DOI: 10.1088/0967-3334/35/7/1509.Peer-Reviewed Original ResearchConceptsLower body negative pressureBlood pressureBody negative pressureCardiac modulationHeart ratePulse pressurePVP waveformsProgressive lower body negative pressureArterial systolic blood pressureFinger arterial blood pressurePeripheral venous pressure waveformsMmHg lower body negative pressureMean blood pressureDiastolic blood pressureSystolic blood pressureArterial blood pressureArterial BP valuesPressure waveformSignificant reductionMild hypovolemiaVenous pressureHemodynamic changesIntravenous siteRespiratory modulationBP values
2012
Modulation of finger photoplethysmographic traces during forced respiration: Venous blood in motion?
Phillips J, Belhaj A, Shafqat K, Langford R, Shelley K, Kyriacou P. Modulation of finger photoplethysmographic traces during forced respiration: Venous blood in motion? Annual International Conference Of The IEEE Engineering In Medicine And Biology Society (EMBC) 2012, 2012: 3644-3647. PMID: 23366717, DOI: 10.1109/embc.2012.6346756.Peer-Reviewed Original ResearchConceptsVenous oxygen saturationOxygen saturationBlood volumeNegative airway pressureAirway pressureVenous bloodArterial saturationRespiratory modulationHealthy volunteersRespiratory frequencyTissue bedsPilot studyResultant modulationArteryModulationFingerBloodPhotoplethysmographic signalsVolunteers
2001
How Does the Plethysmogram Derived from the Pulse Oximeter Relate to Arterial Blood Pressure in Coronary Artery Bypass Graft Patients?
Awad A, Ghobashy M, Stout R, Silverman D, Shelley K. How Does the Plethysmogram Derived from the Pulse Oximeter Relate to Arterial Blood Pressure in Coronary Artery Bypass Graft Patients? Anesthesia & Analgesia 2001, 93: 1466-1471. PMID: 11726424, DOI: 10.1097/00000539-200112000-00022.Peer-Reviewed Original ResearchConceptsMean blood pressureSystolic blood pressureBlood pressurePulse pressurePulse oximeter waveformCoronary artery bypass graft surgeryCoronary artery bypass graft patientsArtery bypass graft surgeryBypass graft surgeryCoronary artery bypassBypass graft patientsRadial artery blood pressure waveformArterial blood pressureBlood pressure waveformArtery bypassGraft patientsGraft surgeryArterial linePatientsFinger oximeterMean differenceClinical applicabilityPulse oximeterPressure waveformOximeterDifferent Responses of Ear and Finger Pulse Oximeter Wave Form to Cold Pressor Test
Awad A, Ghobashy M, Ouda W, Stout R, Silverman D, Shelley K. Different Responses of Ear and Finger Pulse Oximeter Wave Form to Cold Pressor Test. Anesthesia & Analgesia 2001, 92: 1483-1486. PMID: 11375830, DOI: 10.1097/00000539-200106000-00026.Peer-Reviewed Original ResearchConceptsCold pressor testVasoconstrictive responsePressor testIce water immersionPlethysmographic amplitudeVasoconstrictive effectSympathetic toneContralateral handHealthy volunteersSystemic circulationIRB approvalCold stimuliClinical settingEarSignificant disparitiesSignificant changesSuitable monitorFingerResponseEar signalsWater immersionPlethysmography
1997
Arterial–Pulse Oximetry Loops: A New Method of Monitoring Vascular Tone
Shelley K, Bosseau Murray W, Chang D. Arterial–Pulse Oximetry Loops: A New Method of Monitoring Vascular Tone. Journal Of Clinical Monitoring 1997, 13: 223-228. PMID: 9269615, DOI: 10.1023/a:1007361020825.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic alpha-AgonistsAnesthesia, IntravenousArteriesBlood PressureBlood VolumeCalibrationCephalometryDose-Response Relationship, DrugEphedrineFemaleFingersForecastingHeart RateHumansHypotensionIntraoperative ComplicationsMeningiomaMiddle AgedMonitoring, PhysiologicOnline SystemsOximetryPhenylephrinePlethysmographySignal Processing, Computer-AssistedVascular ResistanceVasoconstrictor AgentsVasomotor SystemConceptsPulse oximeter waveformVascular resistanceVascular toneVascular compliancePeripheral vascular complianceVascular compliance changesPeripheral vascular resistanceDose-response curveArterial pressureCase reportArterial waveformClinical informationCompliance changesRelative complianceComplianceTonePhenylephrineOff-line calculation