Specific and cumulative lifetime stressors in the aetiology of major depression: A longitudinal community-based population study
Su Y, D'Arcy C, Li M, O'Donnell K, Caron J, Meaney M, Meng X. Specific and cumulative lifetime stressors in the aetiology of major depression: A longitudinal community-based population study. Epidemiology And Psychiatric Sciences 2022, 31: e3. PMID: 35078547, PMCID: PMC8851045, DOI: 10.1017/s2045796021000779.Peer-Reviewed Original ResearchConceptsGenetic predispositionSubsequent depressionStressful life eventsLifetime stressorsLongitudinal community-based cohort studyPsychosocial stressorsCommunity-based cohort studyCommunity-based population studyStressful eventsMental illness preventionMultivariate logistic regressionHealth-related factorsDevelopment of depressionChildhood maltreatmentMental health promotionEtiology of depressionPresent studyStressful experiencesLife eventsChild-parent bondingCumulative stressful experiencesSouthwest of MontrealPolygenetic risk scoresCohort studySocio-demographic characteristics