2024
Diffusion‐Weighted Imaging Fluid‐Attenuated Inversion Recovery Mismatch on Portable, Low‐Field Magnetic Resonance Imaging Among Acute Stroke Patients
Sorby‐Adams A, Guo J, de Havenon A, Payabvash S, Sze G, Pinter N, Jaikumar V, Siddiqui A, Baldassano S, Garcia‐Guarniz A, Zabinska J, Lalwani D, Peasley E, Goldstein J, Nelson O, Schaefer P, Wira C, Pitts J, Lee V, Muir K, Nimjee S, Kirsch J, Iglesias J, Rosen M, Sheth K, Kimberly W. Diffusion‐Weighted Imaging Fluid‐Attenuated Inversion Recovery Mismatch on Portable, Low‐Field Magnetic Resonance Imaging Among Acute Stroke Patients. Annals Of Neurology 2024, 96: 321-331. PMID: 38738750, PMCID: PMC11293843, DOI: 10.1002/ana.26954.Peer-Reviewed Original ResearchStroke patientsAcute ischemic strokeCut-pointsIschemic strokeStroke patients <Diagnosis of acute ischemic strokeSignal intensity ratioFluid-attenuated inversion recoveryAcute stroke patientsOptimal cut-pointMagnetic resonance imagingDiffusion-weighted imagingDWI-FLAIR mismatchStroke onsetTrained assessorsNational InstituteStrokeThrombolytic interventionNegative predictive valueFLAIR hyperintensitiesPatientsInterobserver agreementHyperacute strokeDiffusion-weightedPredictive value
2021
How to Establish the Outer Limits of Reperfusion Therapy
Wechsler L, Jadhav A, Jovin T, Adeoye O, Albers G, Ansari S, Boltze J, Buchan A, Campbell B, Chaisinanunkul N, Chen C, Derdeyn C, Haddad W, Hill M, Holt W, Houser G, Khatri P, Krtolica A, Landen J, Lansberg M, Liebeskind D, Lyden P, Lynch J, Meinzer C, Mistry E, Mocco J, Nogueira R, Saver J, Savitz S, Schwamm L, Sheth K, Snyder M, Solberg Y, Vagal A, Venkatasubramanian C, Warach S, Ziogas N. How to Establish the Outer Limits of Reperfusion Therapy. Stroke 2021, 52: 3399-3403. PMID: 34470484, DOI: 10.1161/strokeaha.121.035022.Peer-Reviewed Original ResearchConceptsReperfusion therapyAcute ischemic strokeLarge pragmatic trialRoutine clinical practiceDrug Administration approvalTreatment effectsIntravenous alteplaseIschemic strokeStroke onsetEndovascular therapyRandomized trialsPragmatic trialImaging featuresAdministration approvalPlatform trialsSignificant treatment effectEffective treatmentTreatment efficacyAcademic centersClinical practiceTherapyPatientsTrialsMedical communityStatistical significance