2023
Hemorrhagic Conversion of Acute Ischemic Stroke
Zubair A, Sheth K. Hemorrhagic Conversion of Acute Ischemic Stroke. Neurotherapeutics 2023, 20: 705-711. PMID: 37085684, PMCID: PMC10275827, DOI: 10.1007/s13311-023-01377-1.Peer-Reviewed Original ResearchConceptsAcute ischemic strokeHemorrhagic conversionIschemic strokeTreatment of patientsHemorrhagic transformationEndovascular thrombectomySerious complicationsThrombolytic therapyTreatment optionsRisk factorsLeading causePatient outcomesCurrent treatmentTimely managementStrokePatientsTreatmentThrombectomyMorbidityComplicationsReviewPathophysiologyTherapyMortalityDiagnosis
2022
Association of Renin Angiotensin Aldosterone System Inhibitors and Outcomes of Hospitalized Patients With COVID-19
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Association of Renin Angiotensin Aldosterone System Inhibitors and Outcomes of Hospitalized Patients With COVID-19. Critical Care Medicine 2022, 50: e744-e758. PMID: 35894609, PMCID: PMC9469914, DOI: 10.1097/ccm.0000000000005627.Peer-Reviewed Original ResearchConceptsHospitalized COVID-19 patientsAldosterone system inhibitorsAntihypertensive agentsCOVID-19 patientsHigh mortalityHospital mortalitySystem inhibitorsRenin-angiotensin-aldosterone system inhibitorsPrior useCOVID-19Retrospective observational studyCOVID-19 registryHospitalized patientsRAASIsObservational studyPatientsLower mortalityMortalityACEIsHospitalizationARBsMedicationsOutcomesInhibitorsAssociation
2018
History of Intracranial Hemorrhage Is Associated with In-Hospital Mortality in Ischemic Stroke Patients Treated with Intravenous Thrombolytics
Sommaruga S, Chu S, Hwang D, Dearborn J, Sansing L, Cord B, Santarosa C, Samarth G, Petersen N, Gilmore E, Schindler J, Bijlenga P, Schaller K, Matouk C, Sheth K, Falcone G. History of Intracranial Hemorrhage Is Associated with In-Hospital Mortality in Ischemic Stroke Patients Treated with Intravenous Thrombolytics. Journal Of Neurological Surgery Part A Central European Neurosurgery 2018, 79: s1-s27. DOI: 10.1055/s-0038-1660745.Peer-Reviewed Original Research
2016
Measuring the health-related Sustainable Development Goals in 188 countries: a baseline analysis from the Global Burden of Disease Study 2015
Collaborators G, Lim S, Allen K, Bhutta Z, Dandona L, Forouzanfar M, Fullman N, Gething P, Goldberg E, Hay S, Holmberg M, Kinfu Y, Kutz M, Larson H, Liang X, Lopez A, Lozano R, McNellan C, Mokdad A, Mooney M, Naghavi M, Olsen H, Pigott D, Salomon J, Vos T, Wang H, Abajobir A, Abate K, Abbafati C, Abbas K, Abd-Allah F, Abdulle A, Abraham B, Abubakar I, Abu-Raddad L, Abu-Rmeileh N, Abyu G, Achoki T, Adebiyi A, Adedeji I, Afanvi K, Afshin A, Agarwal A, Agrawal A, Kiadaliri A, Ahmadieh H, Ahmed K, Akanda A, Akinyemi R, Akinyemiju T, Akseer N, Al-Aly Z, Alam K, Alam U, Alasfoor D, AlBuhairan F, Aldhahri S, Aldridge R, Alemu Z, Ali R, Alkerwi A, Alkhateeb M, Alla F, Allebeck P, Allen C, Al-Raddadi R, Alsharif U, Altirkawi K, Martin E, Alvis-Guzman N, Amare A, Amberbir A, Amegah A, Amini H, Ammar W, Amrock S, Andersen H, Anderson B, Anderson G, Antonio C, Anwari P, Ärnlöv J, Artaman A, Asayesh H, Asghar R, Atique S, Avokpaho E, Awasthi A, Quintanilla B, Azzopardi P, Bacha U, Badawi A, 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Measuring the health-related Sustainable Development Goals in 188 countries: a baseline analysis from the Global Burden of Disease Study 2015. The Lancet 2016, 388: 1813-1850. PMID: 27665228, PMCID: PMC5055583, DOI: 10.1016/s0140-6736(16)31467-2.Peer-Reviewed Original ResearchConceptsHealth-related Sustainable Development GoalsHealth-related indicatorsGlobal burdenStudy 2015Risk Factors Study 2015Disease Study 2015Hepatitis B incidenceSocio-demographic IndexChildhood overweightNeonatal mortalityTuberculosis incidenceMelinda Gates FoundationMinimal improvementModern contraceptionHealth improvementModerate improvementBaseline analysisMortalityIncidenceGates FoundationBurdenBest predictorMinimal changesSpline regressionGeometric mean
2012
Intracranial Pressure Dose and Outcome in Traumatic Brain Injury
Sheth KN, Stein DM, Aarabi B, Hu P, Kufera JA, Scalea TM, Hanley DF. Intracranial Pressure Dose and Outcome in Traumatic Brain Injury. Neurocritical Care 2012, 18: 26-32. PMID: 23055087, DOI: 10.1007/s12028-012-9780-3.Peer-Reviewed Original ResearchConceptsSevere traumatic brain injuryTraumatic brain injuryElevated intracranial pressureBrain injuryIntracranial pressureFunctional outcomeExtended Glasgow Outcome ScaleCenter observational studyCornerstone of managementGlasgow Outcome ScalePoor functional outcomeIntracranial pressure measurementClinical outcomesOutcome ScaleUniversity HospitalObservational studyProspective patientsCandidate biomarkersInjuryTime doseConclusionsThese resultsOutcomesPatientsMortalityDose