2024
Secondary Prevention in Patients With Stroke Versus Myocardial Infarction: Analysis of 2 National Cohorts
Rivier C, Acosta J, Leasure A, Forman R, Sharma R, de Havenon A, Spatz E, Inzucchi S, Kernan W, Falcone G, Sheth K. Secondary Prevention in Patients With Stroke Versus Myocardial Infarction: Analysis of 2 National Cohorts. Journal Of The American Heart Association 2024, 13: e033322. PMID: 38639369, PMCID: PMC11179946, DOI: 10.1161/jaha.123.033322.Peer-Reviewed Original ResearchMeSH KeywordsAgedAntihypertensive AgentsBlood PressureCross-Sectional StudiesFemaleHumansHydroxymethylglutaryl-CoA Reductase InhibitorsMaleMiddle AgedMyocardial InfarctionPlatelet Aggregation InhibitorsPractice Guidelines as TopicRisk AssessmentRisk FactorsSecondary PreventionStrokeUnited KingdomUnited StatesConceptsMyocardial infarctionPrevention scoreSecondary preventionImplementation of preventive therapyNational cohortUK BiobankAntiplatelet therapy useGuideline-directed therapyPrevention profilesBlood pressure controlAdherence to guideline-directed therapyLow-density lipoprotein controlNeighborhood deprivation levelHistory of strokeVascular risk profileStatin useAntiplatelet useTherapy usePreventive therapyComparison to participantsPrevention criteriaCross-sectional analysisBlood pressurePatientsPressure control
2023
Baseline Cardiovascular Risk Factor Control in Patients With Type 2 Diabetes and Coronary Disease Versus Stroke: Secondary Analysis of Cardiovascular Outcome Trials
Balasubramanian P, Kernan W, Sheth K, Ofstad A, Rosenstock J, Wanner C, Zinman B, Mattheus M, Marx N, Inzucchi S. Baseline Cardiovascular Risk Factor Control in Patients With Type 2 Diabetes and Coronary Disease Versus Stroke: Secondary Analysis of Cardiovascular Outcome Trials. Stroke 2023, 54: 2013-2021. PMID: 37449424, PMCID: PMC10358436, DOI: 10.1161/strokeaha.122.042053.Peer-Reviewed Original ResearchConceptsCardiovascular risk factor controlRisk factor controlCoronary artery diseaseEMPA-REG OUTCOMECardiovascular outcome trialsType 2 diabetesRisk factorsOutcome trialsBlood pressureOdds ratioAntiplatelet/anticoagulant medicationsAntiplatelet/anticoagulant therapyDiabetes cardiovascular outcome trialsSuboptimal risk factor controlCardiovascular risk factorsRecurrent ischemic eventsDiastolic blood pressureSystolic blood pressureRespective odds ratiosFactor controlCross-sectional analysisLogistic regression modelsMacrovascular complicationsStatin useAnticoagulant medicationPolygenic Susceptibility to Hypertension and Blood Pressure Control in Stroke Survivors
Acosta J, Both C, Demarais Z, Conlon C, Leasure A, Torres-Lopez V, de Havenon A, Petersen N, Gill T, Sansing L, Sheth K, Falcone G. Polygenic Susceptibility to Hypertension and Blood Pressure Control in Stroke Survivors. Neurology 2023, 100: e1587-e1597. PMID: 36690452, PMCID: PMC10103110, DOI: 10.1212/wnl.0000000000206763.Peer-Reviewed Original ResearchConceptsWorse BP controlUncontrolled blood pressureDiastolic blood pressureBlood pressureStroke survivorsPolygenic risk scoresBP controlPolygenic susceptibilityMean diastolic blood pressureMean systolic blood pressureStroke Prevention TrialBlood pressure controlSystolic blood pressureResistant hypertensionVascular eventsHemorrhagic strokePrevention trialsVitamin InterventionMultivariable modelRisk scoreGenetic predispositionPressure controlLogistic regressionSurvivorsHypertension
2022
Technical Dissonance in Home Blood Pressure Monitoring After Stroke: Having the Machine, but Not Using Correctly.
Forman R, Viscoli C, Meurer K, Sheth K, Sansing L, de Havenon A, Sharma R, Mariscal M, Kernan W. Technical Dissonance in Home Blood Pressure Monitoring After Stroke: Having the Machine, but Not Using Correctly. American Journal Of Hypertension 2022, 36: 195-200. PMID: 36520024, PMCID: PMC10016067, DOI: 10.1093/ajh/hpac129.Peer-Reviewed Original ResearchConceptsHome blood pressure monitoringBlood pressure monitoringBlood pressurePressure monitoringNon-Hispanic white patientsProportion of patientsCross-sectional studyNon-Hispanic white participantsStroke recurrenceRate of useMost patientsPrimary outcomeWhite patientsRate of possessionPatientsUnderrepresented patientsArm cuffHypertensionStrokeCorrect useWhite participantsSignificant disparitiesEthnic groupsParticipantsQuality of techniqueBlood Pressure and Low‐Density Lipoprotein Cholesterol in Stroke Survivors Versus Controls in the United States From 1999 to 2018
Havenon A, Prabhakaran S, Stulberg E, McLean K, Johnston K, Lansberg M, Grory B, Tirschwell D, Majersik J, Ney J, Sharma R, Sheth K. Blood Pressure and Low‐Density Lipoprotein Cholesterol in Stroke Survivors Versus Controls in the United States From 1999 to 2018. Stroke Vascular And Interventional Neurology 2022, 2 DOI: 10.1161/svin.121.000286.Peer-Reviewed Original Research
2021
Assessment of Discrepancies Between Follow-up Infarct Volume and 90-Day Outcomes Among Patients With Ischemic Stroke Who Received Endovascular Therapy
Ganesh A, Ospel J, Menon B, Demchuk A, McTaggart R, Nogueira R, Poppe A, Almekhlafi M, Hanel R, Thomalla G, Holmin S, Puetz V, van Adel B, Tarpley J, Tymianski M, Hill M, Goyal M, Barber P, Smith E, Bal S, Subramanian S, Peters S, Couillard P, Klein G, Stys P, Coutts S, Wong J, Mitha A, Eesa M, Morrish W, Alqatani S, Kashani N, Venkatesan P, Teleg E, Sitaram A, Graham B, Gaal S, Moussaddy A, Chakraborty D, Maraj N, Lockey A, Chen S, Singh R, Alsultan A, Asunsian R, Tse D, Doshi D, Volny O, Ojha P, Wadhwa A, Marko M, Singh N, Wasyliw S, Ryckborst K, Kenney C, Save S, Jambula A, Newcommon N, Hull G, Blackstock D, Kiszczak S, Zimmel L, Wright M, Jahraus C, Andersen L, Bohn S, Paul J, Buck B, Butcher K, Shuaib A, Jeerakathil T, Jickling G, Emery D, Rempel J, Ower R, Ashforth R, Yeo T, Kotylak T, O;Kelly C, Chow M, Siddiqui M, Saqqur M, D'Souza A, Lloret M, Butt A, Nomani A, Kalashyan H, Thirunavukkarasu S, Jabs J, Fairall P, Piquette L, Phillips S, Green A, Gubitz G, Heidenreich J, Huynh T, Shankar J, Maloney W, Vandorpe R, Schmidt M, Pickett G, Weeks A, Jarrett J, MacDonald D, Arsenault J, Kinnear R, Mandzia J, Mayich M, Boulton M, Bullrich M, Fridman S, Kiwan R, Lee D, Lownie S, Khaw A, Pandey S, Sharma M, Sposato L, Wade K, Beauchamp B, Lambourn L, Amato-Marziali B, Roy D, Deneault N, Deschaintre Y, Gioia L, Jacquin G, Odier C, Stapf C, Iancu D, Raymond J, Weill A, Lapierre M, Jadil N, Jolteus J, Teitelbaum J, Angle M, Hannouche M, Badawy M, Letourneau J, Cortes M, Linnell G, Tampieri D, Vieira L, Legault C, Durcan L, Moore A, Cole E, Magnussen C, Salmon K, Khalil S, Desloges I, Waxman L, Abdon W, Lai S, Dowlatshahi D, Shamy M, Stotts G, Blacquiere D, Lesiuk H, Quateen A, Drake B, Dewar B, Daham Z, Kelly M, Hunter G, Peeling L, Graham B, Whelan R, Garner A, Urroz L, Maley S, Silver F, Casaubon L, Pikula A, Campo M, Schaafsma J, Jaigobin C, Krings T, Pereira V, Agid R, Farb R, Kalman L, Cayley A, Williams J, Stewart T, Misquitta K, Bharatha A, Selchen D, Marotta T, Sarma D, Montanera W, Spears J, Saposnik G, Kostyrko P, Li Y, Parra-Farinas C, Diestro J, Camden M, Verreault S, Mackey A, Audet M, Milot G, Lavoie P, Gariépy J, Collard K, Haché A, Sahlas D, Alshanbari A, Baldwin J, Catanese L, Chen B, Sa Boasquevisque D, Deshmukh A, Knapman J, Lamers S, Larrazabal R, MacMillan S, Mai L, Mattai A, Nayar S, Ng K, Oczkowski W, Perera K, Shawawrah M, Shoamanesh A, Sobhi G, Syed N, Yaher N, Vandervelde C, Wang D, Field T, Van Gaal S, Teal P, Benavente O, Wilson L, Mann S, Yip S, Murphy C, Heran M, Rohr A, Settecase F, Redekop G, Haw C, Maclean G, Murray K, Chiu R, Flexman A, Strecha E, Gayton Y, Yip J, Swartz R, Boulos M, Gladstone D, Yu A, Hopyan J, Khosravani H, Manosalva Alzate H, Southwell A, Kamra M, Lopes K, Kapoor A, da Costa L, Yang V, Dyer E, Shah R, Knowles B, Nichols J, Patterson J, Cope K, Dickerson L, Barton K, Gray K, Massengale T, Miller M, Simpson C, Walker S, Tennyson-Yemm C, Frei D, Bellon R, Atchie B, Kaminsky I, Wilson D, Schraeder N, Arias E, Kodis L, Talley M, Edinger A, Talley T, Dempsey I, Williams L, Williams S, Kupniewski S, Fasbinder B, Snead J, Choe H, Mackenzie L, Weisman D, Kozak O, Shah Q, Gzesh D, Kulandaivel K, Khoury J, Klein B, Bussinger P, Griffin L, DePalmo A, Oliva C, Jadhav A, Jovin T, Kenmuir C, Jankowitz B, Gross B, Rocha M, Starr M, Brown M, Hawkes C, Shah K, Tememe D, Walker G, Patel P, Klein B, Ziayee H, Limaye K, Baxendell L, Glichrist V, Feineigle P, Toseki Haibach K, Van Every C, Desai S, Zulfiqar M, Gibson L, Barrett S, Turkel-Parrella D, Arcot K, DiCrescento S, Farkas J, Filipowski G, Frontera J, Joset D, Liff J, Scher E, McDougall C, Kelly C, Patel A, Monteith S, Starkman S, Atchaneeyasakul K, Burgos A, Anne Y. Chua J, Gaines N, Grunberg I, Guzy J, Liu Z, Maluste N, Ramirez L, Sharma L, Heck D, Brown M, McDonald C, Calderon M, Hargis M, Roels C, Emmady P, Alvi T, Jayaraman M, Cutting S, Smith W, Foley S, Paolucci G, Haas R, Quinn K, Fuller L, Brierley R, Watkins C, Demir N, Lopez G, Vargas A, Osteraas N, Holtz B, Sauvageau E, Aghaebrahim A, Chmayssani M, Naval N, Day J, Dellorso S, Ludwig B, Schemmel D, Ebreo N, Bell K, Lewis L, Delucia M, Haussen D, Frankel M, Bhatt N, Bianchi N, Anderson A, Belagaje S, Liberato B, Rangaraju S, Al-Bayati A, Grossber J, Craft L, Schindler K, Schaad E, Schultz M, Sutherly L, Doppelheuer S, Charlton J, Faggard J, Barbret Z, DukSoo Han E, Walters R, Dolia J, El-Jamal S, Eby B, Saleem Y, Pearl H, Patel K, Rahman H, Butt R, English S, Puri A, Howk M, Singh J, Massari F, DeMacedo Rodrigues K, Kuhn A, English J, Barazangi N, Telischak N, Kim W, Ross J, DeVole N, Redford J, Ferreira M, Ponting K, Shen H, Bedenk A, Patel S, Fernandess J, Ke M, Spokoyny I, Gao B, Tong D, Chen C, Wong C, Choe J, Martin C, Summers D, Boutwell C, Olds K, Crandall S, Eatman J, Akhtar N, Holloway W, Halpin J, Donegan B, Schindler J, Hwang D, Gilmore E, Petersen N, Sheth K, Brown S, Beekman R, George B, Kaddouh F, Falcone G, Wira C, Matouk C, Loomis C, Amin H, Stretz H, Narula R, Jasne A, Sansing L, Agarwal T, Jasak S, Fontaine B, King Z, Kouhn L, Orgass H, Leary M, Nye J, Halbert K, Nystrom K, Neuschatz K, Petrucci D, Coppola A, Joyce T, Hou S, Umekubo M, Nakamura C, Ovando R, Zuniga D, Nien Y, Basto F, Arch A, Jong L, Conrad W, Abbott T, Yao J, Caganap S, Jordan J, Teitelbaum G, Darflinger R, Kelly D, Gupta R, Budzik R, Czerniak J, Groezinger K, Hicks W, Kaskar O, Katz B, Loochtan A, Pema P, Rai V, Vora N, Brown A, Goodman D, Danenbergs B, Gossett M, Bang O, Chung J, Jeon P, Kim K, Lim Y, Hoe Heo J, Nam H, Kim Y, Park H, Hwang I, Ha W, Choi J, Jeong K, Rha J, Park H, Yoon C, Kim B, Sohn S, Kim C, Yoo J, Hong J, Park H, Kim S, Choi M, Bae H, Lee J, Lee J, Jun G, Jeon S, Campbell B, Mitchell P, Yassi N, Davis S, Donnan G, Parsons M, Yan B, Dowling R, Bush S, Wu T, Shan D, Zhao H, Salvaris P, Alemseged F, Ng F, Williams C, Balabanski A, dos Santos A, Ng J, McDonald A, Jackson D, Tsoleridis J, Pesavento L, Kleinig T, Drew R, Cranefield J, Scroop R, Cagi L, Harvey J, Waters M, Thornton J, Brennan R, O'Hare A, Power S, Williams D, Boyle K, Moynihan B, Liddy A, Large M, Cullen A, Walsh R, Martin E, Lynch J, McElroy S, Murphy S, Coveney S, Deegan C, Horgan G, Kelly P, Laffan A, Llamas-Osorio Y, Lynch C, Mac Mahon P, Marnane M, McCabe J, Burns P, Tauro S, Cuddy S, Rennie I, Smyth G, Flynn P, Wiggam I, Kerr E, Gordon P, Fearon P, Roberts G, Patterson C, Adams K, Wells B, McFarland M, Moreira T, Sjöstrand C, Mazya M, Almqvist H, Wahlgren N, Steinberg A, Cooray C, Eriksson E, Thorén M, Keselman B, Ahmed N, Holmberg Å, Axelsson M, Berglund A, Golsari A, Hoppe J, Deb-Chatterji M, Cheng B, Barow E, Schlemm E, Lettow I, Jensen M, Otto D, Jaramillo K, Appelbohm H, Fiehler J, Bester M, Schönfeld M, Brekenfeld C, Holst B, Wortmann G, Koch F, Gerber J, Abramyuk A, Kaiser D, Winzer S, Prakapenia A, Pallesen L, Siepmann T, Barlinn K, Haase K, Sauer A, Psychogios M, Liman J, Brehm A, Maus V, Hollstein N, Reinke A, Neitz G, Schnieder M, Schwarz M, Ibrahim A, Müller J, Meister S, Bäumle B, Chapot R, Pilgram-Pastor S, Wallocha M, Stauder M, Celik E, Stracke P, Müller N, Weber R, Veltkamp R, Nagel S, Ringleb P, Heyse M, Amiri H, Mundiyanapurath S, Chen M, Beyrle E, Beck P, Möhlenbruch M. Assessment of Discrepancies Between Follow-up Infarct Volume and 90-Day Outcomes Among Patients With Ischemic Stroke Who Received Endovascular Therapy. JAMA Network Open 2021, 4: e2132376. PMID: 34739060, PMCID: PMC8571657, DOI: 10.1001/jamanetworkopen.2021.32376.Peer-Reviewed Original ResearchConceptsSerious adverse eventsHigher mRS scoreLower mRS scoresMRS scoreInfarct volumeEndovascular therapyPretreatment factorsPosttreatment factorsBlood pressureHemoglobin levelsFunctional outcomeAnterior Circulation Proximal OcclusionDiscrepant casesHighest FIVTomography/magnetic resonance imagingHigher baseline hemoglobinRecanalization Times (ESCAPE) trialAbsence of diabetesStroke unit careSymptomatic intracerebral hemorrhageCongestive heart failureDiastolic blood pressureRankin Scale scoreMagnetic resonance imagingStepwise model
2019
Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting
Chauhan G, Adams H, Satizabal C, Bis J, Teumer A, Sargurupremraj M, Hofer E, Trompet S, Hilal S, Smith A, Jian X, Malik R, Traylor M, Pulit S, Amouyel P, Mazoyer B, Zhu Y, Kaffashian S, Schilling S, Beecham G, Montine T, Schellenberg G, Kjartansson O, Guðnason V, Knopman D, Griswold M, Windham B, Gottesman R, Mosley T, Schmidt R, Saba Y, Schmidt H, Takeuchi F, Yamaguchi S, Nabika T, Kato N, Rajan K, Aggarwal N, De Jager P, Evans D, Psaty B, Rotter J, Rice K, Lopez O, Liao J, Chen C, Cheng C, Wong T, Ikram M, van der Lee S, Amin N, Chouraki V, DeStefano A, Aparicio H, Romero J, Maillard P, DeCarli C, Wardlaw J, del C. Valdés Hernández M, Luciano M, Liewald D, Deary I, Starr J, Bastin M, Maniega S, Slagboom P, Beekman M, Deelen J, Uh H, Lemmens R, Brodaty H, Wright M, Ames D, Boncoraglio G, Hopewell J, Beecham A, Blanton S, Wright C, Sacco R, Wen W, Thalamuthu A, Armstrong N, Chong E, Schofield P, Kwok J, van der Grond J, Stott D, Ford I, Jukema J, Vernooij M, Hofman A, Uitterlinden A, van der Lugt A, Wittfeld K, Grabe H, Hosten N, von Sarnowski B, Völker U, Levi C, Jimenez-Conde J, Sharma P, Sudlow C, Rosand J, Woo D, Cole J, Meschia J, Slowik A, Thijs V, Lindgren A, Melander O, Grewal R, Rundek T, Rexrode K, Rothwell P, Arnett D, Jern C, Johnson J, Benavente O, Wasssertheil-Smoller S, Lee J, Wong Q, Mitchell B, Rich S, McArdle P, Geerlings M, van der Graaf Y, de Bakker P, Asselbergs F, Srikanth V, Thomson R, McWhirter R, Moran C, Callisaya M, Phan T, Rutten-Jacobs L, Bevan S, Tzourio C, Mather K, Sachdev P, van Duijn C, Worrall B, Dichgans M, Kittner S, Markus H, Ikram M, Fornage M, Launer L, Seshadri S, Longstreth W, Debette S, the International Stroke Genetics Consortium M, Almgren P, Anderson C, Arnett D, Attia J, Ay H, Benavente O, Bevan S, Brown R, Bustamante M, Cheng Y, Cole J, Cotlarciuc I, Cruchaga C, de Bakker P, Delavaran H, Dichgans M, Engström G, Fornage M, Grewal R, Heitsch L, Holliday E, Ibanez L, Ilinca A, Irvin M, Jackson R, Jern C, Jimenez-Conde J, Johnson J, Jood K, Kissela B, Kittner S, Kleindorfer D, Labovitz D, Laurie C, Lee J, Lemmens R, Levi C, Li L, Lindgren A, Maguire J, Markus H, McArdle P, Melander O, Meschia J, Mitchell B, Müller-Nurasyid M, Norrving B, Peddareddygari L, Pera J, Pulit S, Rexrode K, Ribasés M, Roquer J, Rost N, Rothwell P, Rundek T, Sacco R, Schmidt R, Sharma P, Slowik A, Soriano-Tárraga C, Stanne T, Stauch K, Stine O, Sudlow C, Thijs V, Wasssertheil-Smoller S, Weir D, Williams S, Wong Q, Woo D, Worrall B, Xu H, Seshadri S, Hyacinth H, Marini S, Nyquist P, Lewis C, Hansen B, Norrving B, Rosand J, Biffi A, Kourkoulis C, Anderson C, Giese A, Sacco R, Sharma P, Chung J, Kim G, Lubitz S, Bourcier R, Howson J, Granata A, Drazyk A, Markus H, Wardlaw J, Mitchell B, Cole J, Hopewell J, Walters R, Turnbull I, Worrall B, Bis J, Reiner A, Dhar R, Heitsch L, Lee J, Prasad K, Sarnowski C, Aparicio H, Yang Q, Chasman D, Rexrode K, Phuah C, Liu G, Elkind M, Lange L, Rost N, James M, Stewart J, Vojinovic D, Thijs V, Parati E, Boncoraglio G, Zand R, Bijlenga P, Selim M, Grond-Ginsbach C, Strbian D, Tomppo L, Sallinen H, Pfeiffer D, Torres N, Barboza M, Laarman M, Carriero R, Holliday E, Jimenez-Conde J, Soriano C, Gill D, Debette S, Mishra A, Wu J, Ko T, Bione S, Jood K, Tatlisumak T, Holmegaard L, Yue S, bersano A, Pera J, Slowik A, Levi C, Schlicht K, Lemmens R, Ninomiya T, Oberstein S, Lee T, Malik R, Dichgans M, Lindgren A, Wasselius J, Drake M, Melander O, Stenman M, Ilinca A, Crawford K, Lena U, Mateen F, Ay H, Wu O, Schirmer M, Cramer S, Golland P, Brown R, Meschia J, Ross O, Pare G, Chong M, Rundek T, Gwinn K, Chen C, Koenig J, Giralt E, Saleheen D, de Leeuw F, Klijn K, Kamatani Y, Kubo M, Okada Y, Pedersen A, Olsson M, Martín J, Xu H, Tan E, Frid P, Lee C, Tregouet D, Leung T, Choy R, Jern C, Loo K, Rinkel G, Franca P, Cendes I, Carrera C, Fernandez-Cadenas I, Montaner J, Kim H, Owolabi M, Sofat R, Bakker M, Ruigrok Y, Hauer A, Pulit S, van der Laan S, Irvin R, Sargurupremraj M, Pezzini A, Abd-Allah F, Liebeskind D, Traylor M, Tan R, Danesh J, Rutten-Jacobs L, Donatti A, Avelar W, Broderick J, Woo D, Sudlow C, Rannikmae K, McDonough C, van Agtmael T, Walters M, Söderholm M, Lorentzen E, Olsson S, Stanne T, Olsson M, Akinyemi R, Cotlatciuc I, McArdle P, Dave T, Kittner S, Attia J, Faber J, Millwood I, Márquez E, Mancuso M, Vibo R, Korv J, Maguire J, Fornage M, Majersik J, DeHavenon A, Alexander M, Sale M, Southerland A, Owens D, Psaty B, Longstreth W, Wolfe S, Langefeld C, Cruchaga C, Konrad J, Sheth K, Falcone G, Donahue K, Simpkins A, Byorn T, Chan B, Clatworthy P, Florez J, Harshfield E, Hozawa A, Hsu C, Hu C, Ibanez L, Ihara M, Lange M, Lee S, Lee I, Musolino P, Nakatomi H, Park K, Rich S, Riley C, Sung J, Suzuki H, Vo K, Washida K, Ibenez L, Slowik A, Hofman A, Algra A, Reiner A, Doney A, Gschwendtner A, Ilinca A, Giese A, Lindgren A, Vicente A, Norrving B, Nordestgaard B, Mitchell B, Worrall B, Psaty B, Carty C, Sudlow C, Anderson C, Levi C, Satizabal C, Palmer C, Gamble D, Woo D, Saleheen D, Ringelstein E, Valdimarsson E, Holliday E, Davies G, Chauhan G, Pasterkamp G, Boncoraglio G, Kuhlenbäumer G, Thorleifsson G, Falcone G, Pare G, Schmidt H, Delavaran H, Markus H, Aparicio H, Deary I, Cotlarciuc I, Fernandez-Cadenas I, Meschia J, Hopewell J, Liu J, Montaner J, Pera J, Cole J, Attia J, Rosand J, Ferro J, Bis J, Furie K, Stefansson K, Berger K, Kostulas K, Rannikmae K, Ikram M, Benn M, Dichgans M, Farrall M, Pandolfo M, Traylor M, Walters M, Sale M, Nalls M, Fornage M, van Zuydam N, Sharma P, Abrantes P, de Bakker P, Higgins P, Lichtner P, Rothwell P, Amouyel P, Yang Q, Malik R, Schmidt R, Clarke R, Lemmens R, van der Laan S, Pulit S, Abboud S, Oliveira S, Gretarsdottir S, Debette S, Williams S, Bevan S, Kittner S, Seshadri S, Mosley T, Battey T, Tatlisumak T, Thorsteinsdottir U, Thijs V, Longstreth W, Zhao W, Chen W, Cheng Y, Albert M, Albin R, Apostolova L, Arnold S, Asthana S, Atwood C, Baldwin C, Barmada M, Barnes L, Barral S, Beach T, Becker J, Beecham G, Beekly D, Bennett D, Bigio E, Bird T, Blacker D, Boeve B, Boxer A, Burke J, Burns J, Buxbaum J, Byrd G, Cai G, Cairns N, Cantwell L, Cao C, Carlsson C, Carney R, Carrasquillo M, Carroll S, Chui H, Clark D, Cribbs D, Crocco E, Cruchaga C, De Jager P, DeCarli C, Demirci F, Dick M, Dickson D, Duara R, Ertekin-Taner N, Evans D, Faber K, Fallin M, Fallon K, Fardo D, Farlow M, Farrer L, Ferris S, Foroud T, Frosch M, Galasko D, Gearing M, Geschwind D, Ghetti B, Gilbert J, Go R, Goate A, Graff-Radford N, Green R, Griffith P, Growdon J, Haines J, Hakonarson H, Hamilton R, Hamilton-Nelson K, Haroutunian 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Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting. Neurology 2019, 92: 10.1212/wnl.0000000000006851. PMID: 30651383, PMCID: PMC6369905, DOI: 10.1212/wnl.0000000000006851.Peer-Reviewed Original ResearchPopulation-based cohortGenetic risk scoreBrain infarctsLifestyle risk factorsRisk factorsWhite matter hyperintensity burdenLarge population-based cohortPrevious cardiovascular diseaseVascular risk factorsPopulation-based settingBody mass indexSex-adjusted associationsCausal risk factorPopulation-based participantsAdditional large datasetsGenome-wide association studiesIschemic strokeBlood pressureRelated phenotypesHigh BPMass indexBP traitsCardiovascular diseaseRisk scoreGenetic risk loci
2018
105 Decreases in Blood Pressure During Endovascular Stroke Therapy Are Common and Associated With Poor Functional Outcome
Mampre D, Wang A, Sheth K, Tan C, Hebert R, Matouk C, Petersen N. 105 Decreases in Blood Pressure During Endovascular Stroke Therapy Are Common and Associated With Poor Functional Outcome. Neurosurgery 2018, 65: 82. DOI: 10.1093/neuros/nyy303.105.Peer-Reviewed Original Research
2017
Intracerebral Hemorrhage
Stevenson D, Sheth K. Intracerebral Hemorrhage. 2017, 75-91. DOI: 10.1007/978-3-319-48669-7_5.Peer-Reviewed Original ResearchSecondary intracerebral hemorrhageIntracerebral hemorrhageNontraumatic intracerebral hemorrhageIschemic strokeChronic small vessel diseasePrimary intracerebral hemorrhageSmall vessel diseaseCritical care settingHemorrhagic transformationCerebral edemaBlood pressureThorough historyBlood glucoseBrain parenchymaPhysical examVascular malformationsDistinct pathophysiologyIntracranial pressureAnatomical anomaliesCare settingsHemorrhageStrokeFinal manifestationEdemaPatients