2019
Global, regional, and national burden of neurological disorders, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
Collaborators G, Feigin V, Nichols E, Alam T, Bannick M, Beghi E, Blake N, Culpepper W, Dorsey E, Elbaz A, Ellenbogen R, Fisher J, Fitzmaurice C, Giussani G, Glennie L, James S, Johnson C, Kassebaum N, Logroscino G, Marin B, Mountjoy-Venning W, Nguyen M, Ofori-Asenso R, Patel A, Piccininni M, Roth G, Steiner T, Stovner L, Szoeke C, Theadom A, Vollset S, Wallin M, Wright C, Zunt J, Abbasi N, Abd-Allah F, Abdelalim A, Abdollahpour I, Aboyans V, Abraha H, Acharya D, Adamu A, Adebayo O, Adeoye A, Adsuar J, Afarideh M, Agrawal S, Ahmadi A, Ahmed M, Aichour A, Aichour I, Aichour M, Akinyemi R, Akseer N, Al-Eyadhy A, Salman R, Alahdab F, Alene K, Aljunid S, Altirkawi K, Alvis-Guzman N, Anber N, Antonio C, Arabloo J, Aremu O, Ärnlöv J, Asayesh H, Asghar R, Atalay H, Awasthi A, Quintanilla B, Ayuk T, Badawi A, Banach M, Banoub J, Barboza M, Barker-Collo S, Bärnighausen T, Baune B, Bedi N, Behzadifar M, Behzadifar M, Béjot Y, Bekele B, Belachew A, Bennett D, Bensenor I, Berhane A, Beuran M, Bhattacharyya K, Bhutta Z, Biadgo B, Bijani A, Bililign N, Bin Sayeed M, Blazes C, Brayne C, Butt Z, Campos-Nonato I, Cantu-Brito C, Car M, Cárdenas R, Carrero J, Carvalho F, Castañeda-Orjuela C, Castro F, Catalá-López F, Cerin E, Chaiah Y, Chang J, Chatziralli I, Chiang P, Christensen H, Christopher D, Cooper C, Cortesi P, Costa V, Criqui M, Crowe C, Damasceno A, Daryani A, De la Cruz-Góngora V, De la Hoz F, De Leo D, Demoz G, Deribe K, Dharmaratne S, Diaz D, Dinberu M, Djalalinia S, Doku D, Dubey M, Dubljanin E, Duken E, Edvardsson D, El-Khatib Z, Endres M, Endries A, Eskandarieh S, Esteghamati A, Esteghamati S, Farhadi F, Faro A, Farzadfar F, Farzaei M, Fatima B, Fereshtehnejad S, Fernandes E, Feyissa G, Filip I, Fischer F, Fukumoto T, Ganji M, Gankpe F, Garcia-Gordillo M, Gebre A, Gebremichael T, Gelaw B, Geleijnse J, Geremew D, Gezae K, Ghasemi-Kasman M, Gidey M, Gill P, Gill T, Girma E, Gnedovskaya E, Goulart A, Grada A, Grosso G, Guo Y, Gupta R, Gupta R, Haagsma J, Hagos T, Haj-Mirzaian A, Haj-Mirzaian A, Hamadeh R, Hamidi S, Hankey G, Hao Y, Haro J, Hassankhani H, Hassen H, Havmoeller R, Hay S, Hegazy M, Heidari B, Henok A, Heydarpour F, Hoang C, Hole M, Rad E, Hosseini S, Hu G, Igumbor E, Ilesanmi O, Irvani S, Islam M, Jakovljevic M, Javanbakht M, Jha R, Jobanputra Y, Jonas J, Jozwiak J, Jürisson M, Kahsay A, Kalani R, Kalkonde Y, Kamil T, Kanchan T, Karami M, Karch A, Karimi N, Kasaeian A, Kassa T, Kassa Z, Kaul A, Kefale A, Keiyoro P, Khader Y, Khafaie M, Khalil I, Khan E, Khang Y, Khazaie H, Kiadaliri A, Kiirithio D, Kim A, Kim D, Kim Y, Kim Y, Kisa A, Kokubo Y, Koyanagi A, Krishnamurthi R, Defo B, Bicer B, Kumar M, Lacey B, Lafranconi A, Lansingh V, Latifi A, Leshargie C, Li S, Liao Y, Linn S, Lo W, Lopez J, Lorkowski S, Lotufo P, Lucas R, Lunevicius R, Mackay M, Mahotra N, Majdan M, Majdzadeh R, Majeed A, Malekzadeh R, Malta D, Manafi N, Mansournia M, Mantovani L, März W, Mashamba-Thompson T, Massenburg B, Mate K, McAlinden C, McGrath J, Mehta V, Meier T, Meles H, Melese A, Memiah P, Memish Z, Mendoza W, Mengistu D, Mengistu G, Meretoja A, Meretoja T, Mestrovic T, Miazgowski B, Miazgowski T, Miller T, Mini G, Mirrakhimov E, Moazen B, Mohajer B, Mezerji N, Mohammadi M, Mohammadi-Khanaposhtani M, Mohammadibakhsh R, Mohammadnia-Afrouzi M, Mohammed S, Mohebi F, Mokdad A, Monasta L, Mondello S, Moodley Y, Moosazadeh M, Moradi G, Moradi-Lakeh M, Moradinazar M, Moraga P, Velásquez I, Morrison S, Mousavi S, Muhammed O, Muruet W, Musa K, Mustafa G, Naderi M, Nagel G, Naheed A, Naik G, Najafi F, Nangia V, Negoi I, Negoi R, Newton C, Ngunjiri J, Nguyen C, Nguyen L, Ningrum D, Nirayo Y, Nixon M, Norrving B, Noubiap J, Shiadeh M, Nyasulu P, Ogah O, Oh I, Olagunju A, Olagunju T, Olivares P, Onwujekwe O, Oren E, Owolabi M, Mahesh P, Pakpour A, Pan W, Panda-Jonas S, Pandian J, Patel S, Pereira D, Petzold M, Pillay J, Piradov M, Polanczyk G, Polinder S, Postma M, Poulton R, Poustchi H, Prakash S, Prakash V, Qorbani M, Radfar A, Rafay A, Rafiei A, Rahim F, Rahimi-Movaghar V, Rahman M, Rahman M, Rahman M, Rajati F, Ram U, Ranta A, Rawaf D, Rawaf S, Reinig N, Reis C, Renzaho A, Resnikoff S, Rezaeian S, Rezai M, González C, Roberts N, Roever L, Ronfani L, Roro E, Roshandel G, Rostami A, Sabbagh P, Sacco R, Sachdev P, Saddik B, Safari H, Safari-Faramani R, Safi S, Safiri S, Sagar R, Sahathevan R, Sahebkar A, Sahraian M, Salamati P, Zahabi S, Salimi Y, Samy A, Sanabria J, Santos I, Milicevic M, Sarrafzadegan N, Sartorius B, Sarvi S, Sathian B, Satpathy M, Sawant A, Sawhney M, Schneider I, Schöttker B, Schwebel D, Seedat S, Sepanlou S, Shabaninejad H, Shafieesabet A, Shaikh M, Shakir R, Shams-Beyranvand M, Shamsizadeh M, Sharif M, Sharif-Alhoseini, She J, Sheikh A, Sheth K, Shigematsu M, Shiri R, Shirkoohi R, Shiue I, Siabani S, Siddiqi T, Sigfusdottir I, Sigurvinsdottir R, Silberberg D, Silva J, Silveira D, Singh J, Sinha D, Skiadaresi E, Smith M, Sobaih B, Sobhani S, Soofi M, Soyiri I, Sposato L, Stein D, Stein M, Stokes M, Sufiyan M, Sykes B, Sylaja P, Tabarés-Seisdedos R, Ao B, Tehrani-Banihashemi A, Temsah M, Temsah O, Thakur J, Thrift A, Topor-Madry R, Tortajada-Girbés M, Tovani-Palone M, Tran B, Tran K, Truelsen T, Tsadik A, Car L, Ukwaja K, Ullah I, Usman M, Uthman O, Valdez P, Vasankari T, Vasanthan R, Veisani Y, Venketasubramanian N, Violante F, Vlassov V, Vosoughi K, Vu G, Vujcic I, Wagnew F, Waheed Y, Wang Y, Weiderpass E, Weiss J, Whiteford H, Wijeratne T, Winkler A, Wiysonge C, Wolfe C, Xu G, Yadollahpour A, Yamada T, Yano Y, Yaseri M, Yatsuya H, Yimer E, Yip P, Yisma E, Yonemoto N, Yousefifard M, Yu C, Zaidi Z, Bin Zaman S, Zamani M, Zandian H, Zare Z, Zhang Y, Zodpey S, Naghavi M, Murray C, Vos T. Global, regional, and national burden of neurological disorders, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. The Lancet Neurology 2019, 18: 459-480. PMID: 30879893, PMCID: PMC6459001, DOI: 10.1016/s1474-4422(18)30499-x.Peer-Reviewed Original ResearchConceptsNeurological disordersNational burdenAbsolute numberGlobal burdenAge-standardised DALY ratesBayesian meta-regression toolRisk Factors Study 2016Disorder categoriesCauses of DALYsDisMod-MR 2.1Death Ensemble modelDisease Study 2016Age-standardised ratesTension-type headacheCause of deathComparative risk assessment approachDALY ratesDALY burdenModifiable riskMultiple sclerosisFemale ratioNeurological burdenRisk factorsIdiopathic epilepsyTreatment strategiesGlobal, regional, and national burden of stroke, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
Collaborators G, Johnson C, Nguyen M, Roth G, Nichols E, Alam T, Abate D, Abd-Allah F, Abdelalim A, Abraha H, Abu-Rmeileh N, Adebayo O, Adeoye A, Agarwal G, Agrawal S, Aichour A, Aichour I, Aichour M, Alahdab F, Ali R, Alvis-Guzman N, Anber N, Anjomshoa M, Arabloo J, Arauz A, Ärnlöv J, Arora A, Awasthi A, Banach M, Barboza M, Barker-Collo S, Bärnighausen T, Basu S, Belachew A, Belayneh Y, Bennett D, Bensenor I, Bhattacharyya K, Biadgo B, Bijani A, Bikbov B, Bin Sayeed M, Butt Z, Cahuana-Hurtado L, Carrero J, Carvalho F, Castañeda-Orjuela C, Castro F, Catalá-López F, Chaiah Y, Chiang P, Choi J, Christensen H, Chu D, Cortinovis M, Damasceno A, Dandona L, Dandona R, Daryani A, Davletov K, de Courten B, De la Cruz-Góngora V, Degefa M, Dharmaratne S, Diaz D, Dubey M, Duken E, Edessa D, Endres M, FARAON E, Farzadfar F, Fernandes E, Fischer F, Flor L, Ganji M, Gebre A, Gebremichael T, Geta B, Gezae K, Gill P, Gnedovskaya E, Gómez-Dantés H, Goulart A, Grosso G, Guo Y, Gupta R, Haj-Mirzaian A, Haj-Mirzaian A, Hamidi S, Hankey G, Hassen H, Hay S, Hegazy M, Heidari B, Herial N, Hosseini M, Hostiuc S, Irvani S, Islam M, Jahanmehr N, Javanbakht M, Jha R, Jonas J, Jozwiak J, Jürisson M, Kahsay A, Kalani R, Kalkonde Y, Kamil T, Kanchan T, Karch A, Karimi N, Karimi-Sari H, Kasaeian A, Kassa T, Kazemeini H, Kefale A, Khader Y, Khalil I, Khan E, Khang Y, Khubchandani J, Kim D, Kim Y, Kisa A, Kivimäki M, Koyanagi A, Krishnamurthi R, Kumar G, Lafranconi A, Lewington S, Li S, Lo W, Lopez A, Lorkowski S, Lotufo P, Mackay M, Majdan M, Majdzadeh R, Majeed A, Malekzadeh R, Manafi N, Mansournia M, Mehndiratta M, Mehta V, Mengistu G, Meretoja A, Meretoja T, Miazgowski B, Miazgowski T, Miller T, Mirrakhimov E, Mohajer B, Mohammad Y, Mohammadoo-khorasani M, Mohammed S, Mohebi F, Mokdad A, Mokhayeri Y, Moradi G, Morawska L, Velásquez I, Mousavi S, Muhammed O, Muruet W, Naderi M, Naghavi M, Naik G, Nascimento B, Negoi R, Nguyen C, Nguyen L, Nirayo Y, Norrving B, Noubiap J, Ofori-Asenso R, Ogbo F, Olagunju A, Olagunju T, Owolabi M, Pandian J, Patel S, Perico N, Piradov M, Polinder S, Postma M, Poustchi H, Prakash V, Qorbani M, Rafiei A, Rahim F, Rahimi K, Rahimi-Movaghar V, Rahman M, Rahman M, Reis C, Remuzzi G, Renzaho A, Ricci S, Roberts N, Robinson S, Roever L, Roshandel G, Sabbagh P, Safari H, Safari S, Safiri S, Sahebkar A, Zahabi S, Samy A, Santalucia P, Santos I, Santos J, Milicevic M, Sartorius B, Sawant A, Schutte A, Sepanlou S, Shafieesabet A, Shaikh M, Shams-Beyranvand M, Sheikh A, Sheth K, Shibuya K, Shigematsu M, Shin M, Shiue I, Siabani S, Sobaih B, Sposato L, Sutradhar I, Sylaja P, Szoeke C, Ao B, Temsah M, Temsah O, Thrift A, Tonelli M, Topor-Madry R, Tran B, Tran K, Truelsen T, Tsadik A, Ullah I, Uthman O, Vaduganathan M, Valdez P, Vasankari T, Vasanthan R, Venketasubramanian N, Vosoughi K, Vu G, Waheed Y, Weiderpass E, Weldegwergs K, Westerman R, Wolfe C, Wondafrash D, Xu G, Yadollahpour A, Yamada T, Yatsuya H, Yimer E, Yonemoto N, Yousefifard M, Yu C, Zaidi Z, Zamani M, Zarghi A, Zhang Y, Zodpey S, Feigin V, Vos T, Murray C. Global, regional, and national burden of stroke, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. The Lancet Neurology 2019, 18: 439-458. PMID: 30871944, PMCID: PMC6494974, DOI: 10.1016/s1474-4422(19)30034-1.Peer-Reviewed Original ResearchConceptsAge-standardised mortality ratesAge-standardised incidenceSocio-demographic IndexSDI quintileGlobal burdenMortality rateAge-standardised DALY ratesTransient ischemic attackBurden of strokePost-stroke careDisease Study 2016Risk Factor StudyCause-specific mortalityNew stroke casesVerbal autopsy dataYears of lifeEstimates of burdenIschemic attackSDI groupCause of diseaseGBD 2016DALY ratesHaemorrhagic strokeIntracerebral hemorrhageAtrial fibrillation
2016
Global, regional, and national disability-adjusted life-years (DALYs) for 315 diseases and injuries and healthy life expectancy (HALE), 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015
Kassebaum N, Arora M, Barber R, Bhutta Z, Brown J, Carter A, Casey D, Charlson F, Coates M, Coggeshall M, Cornaby L, Dandona L, Dicker D, Erskine H, Ferrari A, Fitzmaurice C, Foreman K, Forouzanfar M, Fullman N, Gething P, Goldberg E, Graetz N, Haagsma J, Hay S, Johnson C, Kemmer L, Khalil I, Kinfu Y, Kutz M, Kyu H, Leung J, Liang X, Lim S, Lozano R, Mensah G, Mikesell J, Mokdad A, Mooney M, Naghavi M, Nguyen G, Nsoesie E, Pigott D, Pinho C, Rankin Z, Reinig N, Salomon J, Sandar L, Smith A, Sorensen R, Stanaway J, Steiner C, Teeple S, Troeger C, Truelsen T, VanderZanden A, Wagner J, Wanga V, Whiteford H, Zhou M, Zoeckler L, Abajobir A, Abate K, Abbafati C, Abbas K, Abd-Allah F, Abraham B, Abubakar I, Abu-Raddad L, Abu-Rmeileh N, Achoki T, Ackerman I, Adebiyi A, Adedeji I, Adsuar J, Afanvi K, Afshin A, Agardh E, Agarwal A, Agarwal S, Ahmed M, Kiadaliri A, Ahmadieh H, Akseer N, Al-Aly Z, Alam K, Alam N, Aldhahri S, Alegretti M, Aleman A, Alemu Z, Alexander L, Ali R, Alkerwi A, Alla F, Allebeck P, Allen C, Alsharif U, Altirkawi K, Martin E, Alvis-Guzman N, Amare A, Amberbir A, Amegah A, Amini H, Ammar W, Amrock S, Anderson G, Anderson B, Antonio C, Anwari P, Ärnlöv J, Arsenijevic V, Artaman A, Asayesh H, Asghar R, Avokpaho E, Awasthi A, Quintanilla B, Azzopardi P, Bacha U, Badawi A, Balakrishnan K, Banerjee A, Barac A, Barker-Collo S, Bärnighausen T, Barregard L, Barrero L, Basu S, Bayou T, Beardsley J, Bedi N, Beghi E, Bell B, Bell M, Benjet C, Bennett D, Bensenor I, Berhane A, Bernabé E, Betsu B, Beyene A, Bhala N, Bhansali A, Bhatt S, Biadgilign S, Bienhoff K, Bikbov B, Abdulhak A, Biryukov S, Bisanzio D, Bjertness E, Blore J, Borschmann R, Boufous S, Bourne R, Brainin M, Brazinova A, Breitborde N, Brugha T, Buchbinder R, Buckle G, Butt Z, Calabria B, Campos-Nonato I, Campuzano J, Carabin H, Carapetis J, Cárdenas R, Carrero J, Castañeda-Orjuela C, Rivas J, Catalá-López F, Cavalleri F, Chang J, Chiang P, Chibalabala M, Chibueze C, Chisumpa V, Choi J, Choudhury L, Christensen H, Ciobanu L, Colistro V, Colomar M, Colquhoun S, Cortinovis M, Crump J, Damasceno A, Dandona R, Dargan P, das Neves J, Davey G, Davis A, Leo D, Degenhardt L, Gobbo L, Derrett S, Jarlais D, deVeber G, Dharmaratne S, Dhillon P, Ding E, Doyle K, Driscoll T, Duan L, Dubey M, Duncan B, Ebrahimi H, Ellenbogen R, Elyazar I, Endries A, Ermakov S, Eshrati B, Esteghamati A, Estep K, Fahimi S, Farid T, Farinha C, Faro A, Farvid M, Farzadfar F, Feigin V, Fereshtehnejad S, Fernandes J, Fernandes J, Fischer F, Fitchett J, Foigt N, Fowkes F, Franklin R, Friedman J, Frostad J, Fürst T, Futran N, Gabbe B, Gankpé F, Garcia-Basteiro A, Gebrehiwot T, Gebremedhin A, Geleijnse J, Gibney K, Gillum R, Ginawi I, Giref A, Giroud M, Gishu M, Giussani G, Godwin W, Gomez-Dantes H, Gona P, Goodridge A, Gopalani S, Gotay C, Goto A, Gouda H, Gugnani H, Guo Y, Gupta R, Gupta R, Gupta V, Gutiérrez R, Hafezi-Nejad N, Haile D, Hailu A, Hailu G, Halasa Y, Hamadeh R, Hamidi S, Hammami M, Handal A, Hankey G, Harb H, Harikrishnan S, Haro J, Hassanvand M, Hassen T, Havmoeller R, Hay R, Hedayati M, Heredia-Pi I, Heydarpour P, Hoek H, Hoffman D, Horino M, Horita N, Hosgood H, Hoy D, Hsairi M, Huang H, Huang J, Iburg K, Idrisov B, Innos K, Inoue M, Jacobsen K, Jauregui A, Jayatilleke A, Jeemon P, Jha V, Jiang G, Jiang Y, Jibat T, Jimenez-Corona A, Jin Y, Jonas J, Kabir Z, Kajungu D, Kalkonde Y, Kamal R, Kan H, Kandel A, Karch A, Karema C, Karimkhani C, Kasaeian A, Katibeh M, Kaul A, Kawakami N, Kazi D, Keiyoro P, Kemp A, Kengne A, Keren A, Kesavachandran C, Khader Y, Khan A, Khan E, Khang Y, Khoja T, Khubchandani J, Kieling C, Kim C, Kim D, Kim Y, Kissoon N, Kivipelto M, Knibbs L, Knudsen A, Kokubo Y, Kolte D, Kopec J, Koul P, Koyanagi A, Defo B, Kuchenbecker R, Bicer B, Kuipers E, Kumar G, Kwan G, Lalloo R, Lallukka T, Larsson A, Latif A, Lavados P, Lawrynowicz A, Leasher J, Leigh J, Leung R, Li Y, Li Y, Lipshultz S, Liu P, Liu Y, Lloyd B, Logroscino G, Looker K, Lotufo P, Lucas R, Lunevicius R, Lyons R, Razek H, Mahdavi M, Majdan M, Majeed A, Malekzadeh R, Malta D, Marcenes W, Martinez-Raga J, Masiye F, Mason-Jones A, Matzopoulos R, Mayosi B, McGrath J, McKee M, Meaney P, Mehari A, Melaku Y, Memiah P, Memish Z, Mendoza W, Meretoja A, Meretoja T, Mesfin Y, Mhimbira F, Millear A, Miller T, Mills E, Mirarefin M, Mirrakhimov E, Mitchell P, Mock C, Mohammad K, Mohammadi A, Mohammed S, Monasta L, Hernandez J, Montico M, Moradi-Lakeh M, Mori R, Mueller U, Mumford J, Murdoch M, Murthy G, Nachega J, Naheed A, Naldi L, Nangia V, Newton J, Ng M, Ngalesoni F, Nguyen Q, Nisar M, Pete P, Nolla J, Norheim O, Norman R, Norrving B, Obermeyer C, Ogbo F, Oh I, Oladimeji O, Olivares P, Olusanya B, Olusanya J, Oren E, Ortiz A, Ota E, Oyekale A, PA M, Park E, Parsaeian M, Patten S, Patton G, Pedro J, Pereira D, Perico N, Pesudovs K, Petzold M, Phillips M, Piel F, Pillay J, Pishgar F, Plass D, Polinder S, Popova S, Poulton R, Pourmalek F, Prasad N, Qorbani M, Rabiee R, Radfar A, Rafay A, Rahimi K, Rahimi-Movaghar V, Rahman M, Rahman M, Rahman S, Rai D, Rai R, Rajsic S, Raju M, Ram U, Ranganathan K, Refaat A, Reitsma M, Remuzzi G, Resnikoff S, Reynolds A, Ribeiro A, Ricci S, Roba H, Rojas-Rueda D, Ronfani L, Roshandel G, Roth G, Roy A, Sackey B, Sagar R, Sanabria J, Sanchez-Niño M, Santos I, Santos J, Sarmiento-Suarez R, Sartorius B, Satpathy M, Savic M, Sawhney M, Schmidt M, Schneider I, Schutte A, Schwebel D, Seedat S, Sepanlou S, Servan-Mori E, Shahraz S, Shaikh M, Sharma R, She J, Sheikhbahaei S, Shen J, Sheth K, Shibuya K, Shigematsu M, Shin M, Shiri R, Sigfusdottir I, Silva D, Silverberg J, Simard E, Singh A, Singh J, Singh P, Skirbekk V, Skogen J, Soljak M, Søreide K, Sorensen R, Sreeramareddy C, Stathopoulou V, Steel N, Stein D, Stein M, Steiner T, Stovner L, Stranges S, Stroumpoulis K, Sunguya B, Sur P, Swaminathan S, Sykes B, Szoeke C, Tabarés-Seisdedos R, Tandon N, Tanne D, Tavakkoli M, Taye B, Taylor H, Ao B, Tegegne T, Tekle D, Terkawi A, Tessema G, Thakur J, Thomson A, Thorne-Lyman A, Thrift A, Thurston G, Tobe-Gai R, Tonelli M, Topor-Madry R, Topouzis F, Tran B, Truelsen T, Dimbuene Z, Tsilimbaris M, Tura A, Tuzcu E, Tyrovolas S, Ukwaja K, Undurraga E, Uneke C, Uthman O, van Gool C, van Os J, Vasankari T, Vasconcelos A, Venketasubramanian N, Violante F, Vlassov V, Vollset S, Wagner G, Wallin M, Wang L, Weichenthal S, Weiderpass E, Weintraub R, Werdecker A, Westerman R, Wijeratne T, Wilkinson J, Williams H, Wiysonge C, Woldeyohannes S, Wolfe C, Won S, Xu G, Yadav A, Yakob B, Yan L, Yano Y, Yaseri M, Ye P, Yip P, Yonemoto N, Yoon S, Younis M, Yu C, Zaidi Z, Zaki M, Zeeb H, Zodpey S, Zonies D, Zuhlke L, Vos T, Lopez A, Murray C. Global, regional, and national disability-adjusted life-years (DALYs) for 315 diseases and injuries and healthy life expectancy (HALE), 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet 2016, 388: 1603-1658. PMID: 27733283, PMCID: PMC5388857, DOI: 10.1016/s0140-6736(16)31460-x.Peer-Reviewed Original ResearchConceptsAge-standardised DALY ratesNon-communicable diseasesSocio-demographic IndexHealthy life expectancyDALY ratesDisease burdenYears of lifeGlobal burdenStudy 2015Risk Factors Study 2015Non-fatal disease burdenHealth lossDisease Study 2015Age 65 yearsLife expectancyCause-specific mortalityHealth system performanceAge-specific death ratesCause mortalityGlobal DALYsTotal DALYsProportion of lifeTotal disabilityEpidemiological patternsEpidemiological transition