2024
Chapter 38 Cybersecurity and blockchain in cardiology
Hall E. Chapter 38 Cybersecurity and blockchain in cardiology. 2024, 367-370. DOI: 10.1016/b978-0-323-90534-3.00006-8.Peer-Reviewed Original Research
2023
Vigorous Exercise in Patients With Hypertrophic Cardiomyopathy
Lampert R, Ackerman M, Marino B, Burg M, Ainsworth B, Salberg L, Tome Esteban M, Ho C, Abraham R, Balaji S, Barth C, Berul C, Bos M, Cannom D, Choudhury L, Concannon M, Cooper R, Czosek R, Dubin A, Dziura J, Eidem B, Emery M, Estes N, Etheridge S, Geske J, Gray B, Hall K, Harmon K, James C, Lal A, Law I, Li F, Link M, McKenna W, Molossi S, Olshansky B, Ommen S, Saarel E, Saberi S, Simone L, Tomaselli G, Ware J, Zipes D, Day S, Abrahms D, Ashley E, Aziz P, Batra A, Cerrone M, Colan S, Erickson C, Ferhaan A, Gollob M, Johnsrude C, Kannankeril P, Kanter R, Li W, Masri A, Murphy A, Nandi D, Perez M, Perry J, Popjes E, Rao R, Rosenthal D, Sanatani S, Semsarian C, Shah M, Skinner J, Tardif J, Towbin J, Turer A, Webster G, Wever-Pinzon O, Wong T. Vigorous Exercise in Patients With Hypertrophic Cardiomyopathy. JAMA Cardiology 2023, 8: 595-605. PMID: 37195701, PMCID: PMC10193262, DOI: 10.1001/jamacardio.2023.1042.Peer-Reviewed Original ResearchConceptsComposite end pointVigorous-intensity exerciseHypertrophic cardiomyopathyVigorous exerciseEnd pointCohort studyExercise categoriesVentricular arrhythmiasPhysical activityPrimary composite end pointMultivariate Cox regression analysisAdjusted hazard ratioProspective cohort studyCox regression analysisLeft ventricular hypertrophyLife-threatening arrhythmiasSudden cardiac arrestImplantable cardioverter defibrillatorHigh rateHCM centersNonvigorous activitiesObservational registryAppropriate shocksExperienced centersHazard ratioCytokinopathy with aberrant cytotoxic lymphocytes and profibrotic myeloid response in SARS-CoV-2 mRNA vaccine–associated myocarditis
Barmada A, Klein J, Ramaswamy A, Brodsky N, Jaycox J, Sheikha H, Jones K, Habet V, Campbell M, Sumida T, Kontorovich A, Bogunovic D, Oliveira C, Steele J, Hall E, Pena-Hernandez M, Monteiro V, Lucas C, Ring A, Omer S, Iwasaki A, Yildirim I, Lucas C. Cytokinopathy with aberrant cytotoxic lymphocytes and profibrotic myeloid response in SARS-CoV-2 mRNA vaccine–associated myocarditis. Science Immunology 2023, 8: eadh3455-eadh3455. PMID: 37146127, PMCID: PMC10468758, DOI: 10.1126/sciimmunol.adh3455.Peer-Reviewed Original ResearchConceptsMRNA vaccinesSARS-CoV-2 mRNA vaccinesSARS-CoV-2 mRNA vaccinationC-reactive protein levelsB-type natriuretic peptidePeripheral blood mononuclear cellsCardiac tissue inflammationDeep immune profilingSerum soluble CD163Vaccine-associated myocarditisCohort of patientsBlood mononuclear cellsCytotoxic T cellsLate gadolinium enhancementHypersensitivity myocarditisElevated troponinMRNA vaccinationImaging abnormalitiesNK cellsImmune profilingKiller cellsMyeloid responseNatriuretic peptideHumoral mechanismsInflammatory cytokinesPriorities to promote participant engagement in the Participant Engagement and Cancer Genome Sequencing (PE-CGS) Network
Schuster A, Crossnohere N, Bachini M, Blair C, Carpten J, Claus E, Colditz G, Ding L, Drake B, Fields R, Janeway K, Kwan B, Lenz H, Ma Q, Mishra S, Paskett E, Rebbeck T, Ricker C, Stern M, Sussman A, Tiner J, Trent J, Verhaak R, Wagle N, Willman C, Bridges J, Network F. Priorities to promote participant engagement in the Participant Engagement and Cancer Genome Sequencing (PE-CGS) Network. Cancer Epidemiology Biomarkers & Prevention 2023, 32: 487-495. PMID: 36791345, PMCID: PMC10068438, DOI: 10.1158/1055-9965.epi-22-0356.Peer-Reviewed Original Research
2022
Electromagnetic interference complicating Impella® use during pediatric ablation
Sullivan J, Maitoza L, Brysiewicz N, Hall E, Beach C. Electromagnetic interference complicating Impella® use during pediatric ablation. Annals Of Pediatric Cardiology 2022, 15: 533-535. PMID: 37152518, PMCID: PMC10158480, DOI: 10.4103/apc.apc_3_22.Peer-Reviewed Original ResearchShort-Term Outcomes After Myopericarditis Related to COVID-19 Vaccination
Pareek M, Steele J, Asnes J, Baldassarre L, Casale L, Desai N, Elder R, Faherty E, Ferguson I, Fishman R, Ghazizadeh Z, Glick L, Hall E, Khera R, Kokkinidis D, Kwan J, O'Marr J, Schussheim A, Tuohy E, Wang Y, Spatz E, Jacoby D, Miller E. Short-Term Outcomes After Myopericarditis Related to COVID-19 Vaccination. JACC Cardiovascular Imaging 2022, 15: 2002-2005. PMID: 36357140, PMCID: PMC9094612, DOI: 10.1016/j.jcmg.2022.03.026.Peer-Reviewed Case Reports and Technical NotesCurrent Practices in Treating Cardiomyopathy and Heart Failure in Duchenne Muscular Dystrophy (DMD): Understanding Care Practices in Order to Optimize DMD Heart Failure Through ACTION
Villa C, Auerbach SR, Bansal N, Birnbaum BF, Conway J, Esteso P, Gambetta K, Hall EK, Kaufman BD, Kirmani S, Lal AK, Martinez HR, Nandi D, O’Connor M, Parent JJ, Raucci FJ, Shih R, Shugh S, Soslow JH, Tunuguntla H, Wittlieb-Weber CA, Kinnett K, Cripe L. Current Practices in Treating Cardiomyopathy and Heart Failure in Duchenne Muscular Dystrophy (DMD): Understanding Care Practices in Order to Optimize DMD Heart Failure Through ACTION. Pediatric Cardiology 2022, 43: 977-985. PMID: 35024902, PMCID: PMC8756173, DOI: 10.1007/s00246-021-02807-7.Peer-Reviewed Original ResearchConceptsVentricular assist deviceDuchenne muscular dystrophyHeart failureTherapeutic approachesAdvanced Cardiac Therapies Improving Outcomes NetworkDMD patientsBeta-blocker therapyMuscular dystrophyImplantable cardioverter defibrillatorAldosterone antagonistsSystolic dysfunctionCardiology providersHolter monitoringPrimary preventionDestination therapyPediatric cardiologistsCardiac careLeading causeOutcomes NetworkCardioverter defibrillatorCardiac diseaseClinical careMuscle therapyEnzyme inhibitorsCare practices
2021
Valsartan in early-stage hypertrophic cardiomyopathy: a randomized phase 2 trial.
Ho CY, Day SM, Axelsson A, Russell MW, Zahka K, Lever HM, Pereira AC, Colan SD, Margossian R, Murphy AM, Canter C, Bach RG, Wheeler MT, Rossano JW, Owens AT, Bundgaard H, Benson L, Mestroni L, Taylor MRG, Patel AR, Wilmot I, Thrush P, Vargas JD, Soslow JH, Becker JR, Seidman CE, Lakdawala NK, Cirino AL, VANISH Investigators., Burns KM, McMurray JJV, MacRae CA, Solomon SD, Orav EJ, Braunwald E. Valsartan in early-stage hypertrophic cardiomyopathy: a randomized phase 2 trial. Nat Med 2021 doi: 10.1038/s41591-021-01505-4. PMID: 34556856.Peer-Reviewed Original ResearchSymptomatic Acute Myocarditis in 7 Adolescents After Pfizer-BioNTech COVID-19 Vaccination
Marshall M, Ferguson ID, Lewis P, Jaggi P, Gagliardo C, Collins JS, Shaughnessy R, Caron R, Fuss C, Corbin KJE, Emuren L, Faherty E, Hall EK, Di Pentima C, Oster ME, Paintsil E, Siddiqui S, Timchak DM, Guzman-Cottrill JA. Symptomatic Acute Myocarditis in 7 Adolescents After Pfizer-BioNTech COVID-19 Vaccination. Pediatrics 2021, 148: e2021052478. PMID: 34088762, DOI: 10.1542/peds.2021-052478.Peer-Reviewed Original ResearchConceptsPfizer-BioNTech COVID-19 vaccinationCOVID-19 vaccinationAcute myocarditisClinical courseLate gadolinium enhancement (LGE) characteristicsPolymerase chain reaction test resultsTranscription polymerase chain reaction (RT-PCR) test resultsVaccine Adverse Event Reporting SystemCoronavirus disease 2019 (COVID-19) vaccinationAcute COVID-19Multisystem inflammatory syndromeAdverse Event Reporting SystemImportant adverse eventsTime of presentationNonsteroidal antiinflammatory drugsHealthy male adolescentsGadolinium enhancement characteristicsEvent Reporting SystemReaction test resultsChest painElevated troponinInflammatory syndromeIntravenous immunoglobulinAdverse eventsSecond dose
2020
Hair and skin predict cardiomyopathies: Carvajal and erythrokeratodermia cardiomyopathy syndromes
Sun Q, Lee L, Hall EK, Choate KA, Elder RW. Hair and skin predict cardiomyopathies: Carvajal and erythrokeratodermia cardiomyopathy syndromes. Pediatric Dermatology 2020, 38: 31-38. PMID: 33275305, DOI: 10.1111/pde.14478.Peer-Reviewed Original ResearchConceptsCongestive heart failureCardiac evaluationHeart failureHeart diseaseSudden deathNail abnormalitiesCardiac pathologyNovel therapeuticsCardiomyopathy syndromeFatal consequencesYoung childrenPatientsWarning signsSyndromeFamily membersCardiocutaneous disorderSkinCharacteristic hairCardiomyopathyAbnormalitiesDiseasePathologyFamilial Dilated Cardiomyopathy Associated With a Novel Combination of Compound Heterozygous TNNC1 Variants
Landim-Vieira M, Johnston JR, Ji W, Mis EK, Tijerino J, Spencer-Manzon M, Jeffries L, Hall EK, Panisello-Manterola D, Khokha MK, Deniz E, Chase PB, Lakhani SA, Pinto JR. Familial Dilated Cardiomyopathy Associated With a Novel Combination of Compound Heterozygous TNNC1 Variants. Frontiers In Physiology 2020, 10: 1612. PMID: 32038292, PMCID: PMC6990120, DOI: 10.3389/fphys.2019.01612.Peer-Reviewed Original ResearchCardiac muscle preparationsIsometric forcePatient variantsEarly-onset DCMDilated Cardiomyopathy AssociatedCompound heterozygous variantsSteady-state isometric forceCardiomyopathy AssociatedContractile functionMuscle preparationsCardiomyopathy phenotypeHeterozygous variantsCardiac phenotypeMyofilament CaSarcomeric genesFurther studiesPhysical Activity in Individuals With the Long Qt Syndrome: Baseline Data From the Lifestyle and Exercise in Long Qt Study (live Lqts)
https://doi.org/10.1161/circ.142.suppl_3.14500Peer-Reviewed Original ResearchBlockchains in Medicine
Intelligence-Based Medicine: Artificial Intelligence and Human Cognition in Clinical Medicine and Healthcare 1st EditionBooksChapter 6 Other Key Concepts in Artificial Intelligence
Chang A, Rhee K, Mousses S, Nahar J, Lane S, Ayalasomayajula F, Hall E, Chou T, Murickan G, Van Demark D. Chapter 6 Other Key Concepts in Artificial Intelligence. 2020, 141-180. DOI: 10.1016/b978-0-12-823337-5.00006-8.Peer-Reviewed Original ResearchNatural language processingCognitive computingIntersection of AIArtificial intelligence domainInternet of ThingsRobotic Process AutomationNatural language understandingRealm of AICloud computingAI resourcesDeep learningAI technologyArtificial intelligenceMachine learningAI domainIntelligence domainIBM WatsonExtended realityLanguage understandingProcess automationComputer scienceLanguage processingPattern recognitionComputingAutonomous systems
2019
Baseline Characteristics of the VANISH Cohort
Axelsson Raja A, Shi L, Day SM, Russell M, Zahka K, Lever H, Colan SD, Margossian R, Hall EK, Becker J, Jefferies JL, Patel AR, Choudhury L, Murphy AM, Canter C, Bach R, Taylor M, Mestroni L, Wheeler MT, Benson L, Owens AT, Rossano J, Lin KY, Pahl E, Pereira AC, Bundgaard H, Lewis GD, Vargas JD, Cirino AL, McMurray JJV, MacRae CA, Solomon SD, Orav EJ, Braunwald E, Ho CY. Baseline Characteristics of the VANISH Cohort. Circulation Heart Failure 2019, 12: e006231. PMID: 31813281, PMCID: PMC7219518, DOI: 10.1161/circheartfailure.119.006231.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAngiotensin II Type 1 Receptor BlockersBrazilCanadaCardiomyopathy, HypertrophicChildDenmarkDisease ProgressionDouble-Blind MethodFemaleGenetic Predisposition to DiseaseHumansMaleMiddle AgedMutationPhenotypeRecovery of FunctionSarcomeresTime FactorsTreatment OutcomeUnited StatesValsartanYoung AdultConceptsAngiotensin receptor blockersHypertrophic cardiomyopathyReceptor blockersBaseline characteristicsImaging abnormalitiesPrimary cohortMutation carriersNew York Heart Association class IINew York Heart Association classFunctional class II symptomsOlder ageClass II symptomsNonobstructive hypertrophic cardiomyopathyNormal functional capacityPrevious trialsVentricular wall thicknessPeak oxygen consumptionPlacebo-controlled designCardiac magnetic resonanceGene mutation carriersLate gadolinium enhancementVANISH trialAdvanced diseaseAssociation classVentricular hypertrophy
2018
Text Messaging in Oncology: A Review of the Landscape
Mougalian SS, Gross CP, Hall EK. Text Messaging in Oncology: A Review of the Landscape. JCO Clinical Cancer Informatics 2018, 2: 1-9. PMID: 30652579, DOI: 10.1200/cci.17.00162.Peer-Reviewed Original Research
2016
Vitamin D Status After Cardiopulmonary Bypass in Children With Congenital Heart Disease
Zahr R, Faustino EV, Carpenter T, Kirshbom P, Hall EK, Fahey JT, Kandil SB. Vitamin D Status After Cardiopulmonary Bypass in Children With Congenital Heart Disease. Journal Of Intensive Care Medicine 2016, 32: 508-513. PMID: 27251108, DOI: 10.1177/0885066616652077.Peer-Reviewed Original ResearchConceptsCongenital heart diseasePg/mLCardiopulmonary bypassVitamin D binding proteinD binding proteinHeart diseaseAlbumin levelsTime pointsVitamin D deficiencyVitamin D statusProspective observational studyMean levelsFree fractionD deficiencyD statusDihydroxyvitamin DObservational studySurgeryBinding proteinBypassDiseaseMeasures analysisChildrenDeficiencyML
2015
Effect of the decrease in dialysate sodium in pediatric patients on chronic hemodialysis
Marsenic O, Anderson M, Couloures KG, Hong WS, Hall E, Dahl N. Effect of the decrease in dialysate sodium in pediatric patients on chronic hemodialysis. Hemodialysis International 2015, 20: 277-285. PMID: 26663617, DOI: 10.1111/hdi.12384.Peer-Reviewed Original ResearchConceptsPediatric patientsDialysate sodiumPediatric HD populationPediatric hemodialysis populationStandard HD sessionInterdialytic weight gainMEq/LChronic HDHemodialysis populationChronic hemodialysisHD sessionHD populationInterdialytic periodAdult studiesPatientsWeight gainStudy periodLack of concordanceFurther studiesSodium gradientFirst reportHypertensionPredialysisHemodialysisPopulation
2014
Giant aneurysm of the atrial appendages in infants
Lang SM, Zaidi A, Geva T, Sanders S, del Nido P, Hall E. Giant aneurysm of the atrial appendages in infants. Annals Of Pediatric Cardiology 2014, 7: 130-134. PMID: 24987260, PMCID: PMC4070203, DOI: 10.4103/0974-2069.132489.Peer-Reviewed Original Research
2011
Doppler tissue imaging in children following cardiac transplantation: A comparison to catheter derived hemodynamics
Goldberg DJ, Quartermain MD, Glatz AC, Hall EK, Davis E, Kren SA, Hanna BD, Cohen MS. Doppler tissue imaging in children following cardiac transplantation: A comparison to catheter derived hemodynamics. Pediatric Transplantation 2011, 15: 488-494. PMID: 21518161, PMCID: PMC3140578, DOI: 10.1111/j.1399-3046.2011.01503.x.Peer-Reviewed Original ResearchConceptsHigh-grade cellular rejectionTricuspid EHeart transplantationCellular rejectionFilling pressureMean RAPVentricular filling pressurePediatric heart transplantationMean PCWPCardiac transplantationHeart transplantDoppler tissueElevated PCWPMyocardial velocitiesProspective analysisTransplantationRejection statusPCWPChildrenSubjectsPrevious studiesTransplantHemodynamicsRejection