2015
Predictors of Complete Response and Disease Recurrence Following Chemoradiation for Rectal Cancer
Bitterman DS, Salgado L, Moore HG, Sanfilippo NJ, Gu P, Hatzaras I, Du KL. Predictors of Complete Response and Disease Recurrence Following Chemoradiation for Rectal Cancer. Frontiers In Oncology 2015, 5: 286. PMID: 26734570, PMCID: PMC4686647, DOI: 10.3389/fonc.2015.00286.Peer-Reviewed Original ResearchDistant metastasis-free survivalDisease-free survivalComplete responseLocoregional controlCarcinoembryonic antigenAnal vergeIndependent predictorsRectal cancerTumor sizeCR groupNode-positive rectal cancerThree-year locoregional controlNode-positive diseaseDistance of tumorNon-operative managementMetastasis-free survivalLong-term outcomesTreatment response evaluationDefinitive chemoradiationRectal patientsNeoadjuvant chemoradiationMost patientsNode positivityOverall survivalSelect patientsComparison of anal cancer outcomes in public and private hospital patients treated at a single radiation oncology center
Bitterman DS, Grew D, Gu P, Cohen RF, Sanfilippo NJ, Leichman CG, Leichman LP, Moore HG, Gold HT, Du KL. Comparison of anal cancer outcomes in public and private hospital patients treated at a single radiation oncology center. Journal Of Gastrointestinal Oncology 2015, 6: 524-33. PMID: 26487947, PMCID: PMC4570920, DOI: 10.3978/j.issn.2078-6891.2015.061.Peer-Reviewed Original ResearchDisease-free survivalColostomy-free survivalOverall survivalPublic hospital patientsPrivate hospital patientsHospital patientsRadiotherapy durationFree survivalRadiotherapy delayRadiation therapyHigher clinical T stageThree-year overall survivalPoor disease-free survivalPrivate hospitalsAdvanced anal cancerAnal cancer outcomesSame cancer centerUnplanned treatment breaksClinical T stageAnal cancer patientsKaplan-Meier methodLow socioeconomic status populationClinical stage groupsLog-rank testProportional hazards model
2014
Chemoradiation Therapy versus Chemotherapy Alone for Gastric Cancer after R0 Surgical Resection: A Meta-Analysis of Randomized Trials
Min C, Bangalore S, Jhawar S, Guo Y, Nicholson J, Formenti SC, Leichman LP, Du KL. Chemoradiation Therapy versus Chemotherapy Alone for Gastric Cancer after R0 Surgical Resection: A Meta-Analysis of Randomized Trials. Oncology 2014, 86: 79-85. PMID: 24435019, DOI: 10.1159/000354641.Peer-Reviewed Original ResearchConceptsDisease-free survivalAdjuvant chemoradiationSurgical resectionOverall survivalRandomized trialsGastric cancerMantel-Haenszel random-effects modelHigher disease-free survivalCategory 1 recommendationNew systemic agentsR0 surgical resectionCurrent national guidelinesSignificant differencesRandom-effects modelAdjuvant chemotherapyPerioperative chemotherapyChemotherapy regimenChemoradiation therapySystemic agentsPrimary outcomeGastric adenocarcinomaClinical trialsChemoradiationNational guidelinesResection