Radiation therapy improves survival in rectal small cell cancer - Analysis of Surveillance Epidemiology and End Results (SEER) data
Modrek AS, Hsu HC, Leichman CG, Du KL. Radiation therapy improves survival in rectal small cell cancer - Analysis of Surveillance Epidemiology and End Results (SEER) data. Radiation Oncology 2015, 10: 101. PMID: 25902707, PMCID: PMC4464878, DOI: 10.1186/s13014-015-0411-y.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAntineoplastic Agents, AlkylatingAntineoplastic Combined Chemotherapy ProtocolsCarcinoma, Small CellCombined Modality TherapyDigestive System Surgical ProceduresFemaleHumansKaplan-Meier EstimateMaleMiddle AgedOrganoplatinum CompoundsProportional Hazards ModelsRectal NeoplasmsRetrospective StudiesSEER ProgramSurvival AnalysisUnited StatesConceptsRadiation therapyOverall survivalRectal cancerSurveillance EpidemiologyCell carcinomaSEER dataMultivariate Cox proportional hazards modelCox proportional hazards modelBackgroundSmall cell carcinomaMethodsThe SEER databaseCancer-directed therapyEnd Results (SEER) databaseUnadjusted hazard ratioEnd Results (SEER) dataKaplan-Meier methodOverall survival rateYear of diagnosisSmall cell carcinomaSignificant survival advantagePearson's chi-square testProportional hazards modelOnly significant factorChi-square testChemotherapy usageLocoregional casesAnal cancer outcomes in patients treated with intensity modulated versus 3-dimensional chemoradiotherapy.
Cooper B, Grew D, Bitterman D, Sanfilippo N, Du K. Anal cancer outcomes in patients treated with intensity modulated versus 3-dimensional chemoradiotherapy. Journal Of Clinical Oncology 2015, 33: 662-662. DOI: 10.1200/jco.2015.33.3_suppl.662.Peer-Reviewed Original ResearchDistant metastasis-free survivalLocal recurrence-free survivalColostomy-free survivalOverall survivalTreatment interruptionLymph nodesTreatment breaksSkin toxicityRadiation therapyThree-year overall survivalAnal cancer outcomesGrowth factor supportRecurrence-free survivalMetastasis-free survivalSquamous cell carcinomaKaplan-Meier survivalConformal radiation therapyRadiation techniquesLog-rank statisticsChi-square testAcute gastrointestinalAcute GIDefinitive chemoradiotherapyIMRT cohortRTOG 0529