2018
Evolving Insights into the Molecular Neuropathology of Diffuse Gliomas in Adults
Barthel F, Johnson K, Wesseling P, Verhaak R. Evolving Insights into the Molecular Neuropathology of Diffuse Gliomas in Adults. Neurologic Clinics 2018, 36: 421-437. PMID: 30072063, PMCID: PMC6322909, DOI: 10.1016/j.ncl.2018.04.002.Peer-Reviewed Original ResearchConceptsDiffuse gliomasWorld Health Organization classificationAppropriate treatment regimensTreatment regimensOrganization classificationClinical classificationClinical relevanceMolecular neuropathologyPatient's lifeGliomasMolecular profilingMolecular biomarkersIntratumoral heterogeneityNeuropathologyAdultsOverview of studiesBiomarkersGene expressionMolecular analysisRegimensFacilitate selection
2014
Genome-wide DNA methylation profiles in progression to in situand invasive carcinoma of the breast with impact on gene transcription and prognosis
Fleischer T, Frigessi A, Johnson K, Edvardsen H, Touleimat N, Klajic J, Riis M, Haakensen V, Wärnberg F, Naume B, Helland Å, Børresen-Dale A, Tost J, Christensen B, Kristensen V. Genome-wide DNA methylation profiles in progression to in situand invasive carcinoma of the breast with impact on gene transcription and prognosis. Genome Biology 2014, 15: 435. PMID: 25146004, PMCID: PMC4165906, DOI: 10.1186/s13059-014-0435-x.Peer-Reviewed Original ResearchConceptsGenome-wide DNA methylation profilesDNA methylation profilesMethylation profilesInvasive breast carcinomaProgression of cancerBreast carcinomaDNA methylation alterationsPrognostic signatureDNA methylation-based markersCancer Genome AtlasDNA methylationGene transcriptionMethylation changesMethylation-based markersEpigenetic changesMethylation alterationsSurvival of patientsGene expressionBreast cancer patientsMethylation levelsNormal breast tissueBreast cancer samplesClinical decision makingGenesGenome Atlas