2017
Preoperative optimization for major hepatic resection
Walcott-Sapp S, Billingsley KG. Preoperative optimization for major hepatic resection. Langenbeck's Archives Of Surgery 2017, 403: 23-35. PMID: 29150719, DOI: 10.1007/s00423-017-1638-x.Peer-Reviewed Original ResearchConceptsMajor hepatic resectionHepatic resectionExercise capacityLiver diseaseMajor liver resectionUnderlying liver diseaseChronic liver diseasePrimary hepatobiliary malignanciesPathophysiology of changesPreoperative preparation programHepatectomy patientsPreoperative optimizationExercise toleranceMajor hepatectomyPostoperative complicationsLiver resectionMetastatic diseasePostoperative outcomesHepatobiliary malignanciesPreoperative evaluationExercise programExercise trainingFatty infiltrationHepatic steatosisMuscle strength
2012
Loss of expression of the cancer stem cell marker aldehyde dehydrogenase 1 correlates with advanced-stage colorectal cancer
Hessman C, Bubbers E, Billingsley K, Herzig D, Wong M. Loss of expression of the cancer stem cell marker aldehyde dehydrogenase 1 correlates with advanced-stage colorectal cancer. The American Journal Of Surgery 2012, 203: 649-653. PMID: 22405917, PMCID: PMC4285581, DOI: 10.1016/j.amjsurg.2012.01.003.Peer-Reviewed Original ResearchConceptsAldehyde dehydrogenase 1Cancer stem cellsClinical outcomesLoss of expressionCSC marker aldehyde dehydrogenase 1Advanced stage colorectal cancerMarker expressionMetastatic CRC samplesAmerican Joint CommitteeLate-stage diseaseColorectal cancer progressionEffective therapeutic targetNonmetastatic CRCMetastatic diseaseEarly CRCALDH1 expressionColorectal cancerCancer stageCRC tumorsCRC samplesTumors variesDisease prognosisNonmetastatic tumorsTherapeutic targetJoint Committee
2009
Evolving Preoperative Evaluation of Patients with Pancreatic Cancer: Does Laparoscopy Have a Role in the Current Era?
Mayo S, Austin D, Sheppard B, Mori M, Shipley D, Billingsley K. Evolving Preoperative Evaluation of Patients with Pancreatic Cancer: Does Laparoscopy Have a Role in the Current Era? Journal Of The American College Of Surgeons 2009, 208: 87-95. PMID: 19228509, DOI: 10.1016/j.jamcollsurg.2008.10.014.Peer-Reviewed Original ResearchConceptsPancreatic adenocarcinomaDiagnostic laparoscopyMetastatic diseaseSurgical explorationEndoscopic ultrasonographyDual-phase CT scanMultivariate logistic regression modelCornerstone of stagingPreoperative weight lossMedical record reviewSubset of patientsPopulation-based studyPancreatic cancer patientsState Cancer RegistrySound clinical approachCurrent imaging modalitiesCombination of CTCurrent staging techniquesLogistic regression modelsCurative intentPotential resectabilityResectable patientsLaparoscopic stagingPreoperative evaluationPrimary outcome
2006
Outcome Following Surgical Therapy for Gastrointestinal Stromal Tumors
Gupta M, Sheppard B, Corless C, MacDonell K, Blanke C, Billingsley K. Outcome Following Surgical Therapy for Gastrointestinal Stromal Tumors. Journal Of Gastrointestinal Surgery 2006, 10: 1099-1105. PMID: 16966028, DOI: 10.1016/j.gassur.2006.05.014.Peer-Reviewed Original ResearchConceptsGastrointestinal stromal tumorsMultivisceral resectionStromal tumorsMetastatic diseaseSurgical resectionImatinib mesylateDuodenal gastrointestinal stromal tumorKIT-positive gastrointestinal stromal tumoursCox proportional hazards modelPercent of patientsComplete surgical resectionKaplan-Meier methodLog-rank analysisPresence of metastasesLimits of resectionProportional hazards modelMitotic indexHigh mitotic indexActuarial survivalPostoperative survivalIncomplete resectionSurgical therapyComplete resectionImproved survivalIndependent predictorsCurrent Status of Colorectal Cancer Therapy
Strother J, Billingsley K, Hung A, Blanke C. Current Status of Colorectal Cancer Therapy. 2006, 273-285. DOI: 10.1007/978-1-59745-172-7_23.Peer-Reviewed Original Research