1999
A paradigm for finding genes for a complex human trait: Polycystic ovary syndrome and follistatin
Odunsi K, Kidd K. A paradigm for finding genes for a complex human trait: Polycystic ovary syndrome and follistatin. Proceedings Of The National Academy Of Sciences Of The United States Of America 1999, 96: 8315-8317. PMID: 10411866, PMCID: PMC33617, DOI: 10.1073/pnas.96.15.8315.Peer-Reviewed Original ResearchLinkage Disequilibrium at the ADH2 and ADH3 Loci and Risk of Alcoholism
Osier M, Pakstis A, Kidd J, Lee J, Yin S, Ko H, Edenberg H, Lu R, Kidd K. Linkage Disequilibrium at the ADH2 and ADH3 Loci and Risk of Alcoholism. American Journal Of Human Genetics 1999, 64: 1147-1157. PMID: 10090900, PMCID: PMC1377839, DOI: 10.1086/302317.Peer-Reviewed Original ResearchMeSH KeywordsAlcohol DehydrogenaseAlcoholismAllelesBase SequenceChinaChromosomes, Human, Pair 4Cloning, MolecularGene FrequencyGenetic Predisposition to DiseaseGenetic VariationHaplotypesHumansIndians, Central AmericanLinkage DisequilibriumMexicoMolecular Sequence DataMultigene FamilyNative Hawaiian or Other Pacific IslanderPolymorphism, Single NucleotideRacial GroupsTaiwanConceptsProportion of chromosomesAlcohol dehydrogenase geneDehydrogenase geneChromosome 4Functional variantsChromosomesLinkage disequilibriumADH2Functional polymorphismsADH3Allele frequenciesPairwise disequilibriumGenesIntronic polymorphismDisequilibriumPolymorphismDifferent efficienciesRisk of alcoholismHigher VmaxClass I alcohol dehydrogenase (ADH) genesVariantsLociKbHaplotypesPopulation
1997
A Novel, Heritable, Expanding CTG Repeat in an Intron of the SEF2-1 Gene on Chromosome 18q21.1
Breschel T, McInnis M, Margolis R, Sirugo G, Corneliussen B, Simpson S, McMahon F, MacKinnon D, Xu J, Pleasant N, Huo Y, Ashworth R, Grundstrom C, Grundstrom T, Kidd K, DePaulo J, Ross C. A Novel, Heritable, Expanding CTG Repeat in an Intron of the SEF2-1 Gene on Chromosome 18q21.1. Human Molecular Genetics 1997, 6: 1855-1863. PMID: 9302263, DOI: 10.1093/hmg/6.11.1855.Peer-Reviewed Original ResearchMeSH KeywordsAllelesBase SequenceBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsBipolar DisorderBlotting, SouthernCell LineChromosomes, Human, Pair 18Cloning, MolecularDNA-Binding ProteinsFemaleGene FrequencyHelix-Loop-Helix MotifsHumansIntronsMaleMolecular Sequence DataPedigreeSequence AnalysisTCF Transcription FactorsTrans-ActivatorsTranscription Factor 4Transcription Factor 7-Like 2 ProteinTranscription FactorsTrinucleotide RepeatsConceptsCEPH reference pedigreesSouthern blot analysisReference pedigreesUnstable alleleDNA binding proteinTriplet repeat mutationBlot analysisCTG repeatsTranscriptional regulationGenomic digestsHuman chromosomesKb cloneStable allelesCandidate genesAbnormal phenotypeBinding proteinRepeatsRepeat lociBipolar pedigreesGenesChromosome 18q21.1Repeat mutationsSomatic mutationsIntronsAllelesConcerted evolution of the tandemly repeated genes encoding human U2 snRNA (the RNU2 locus) involves rapid intrachromosomal homogenization and rare interchromosomal gene conversion
Liao D, Pavelitz T, Kidd J, Kidd K, Weiner A. Concerted evolution of the tandemly repeated genes encoding human U2 snRNA (the RNU2 locus) involves rapid intrachromosomal homogenization and rare interchromosomal gene conversion. The EMBO Journal 1997, 16: 588-598. PMID: 9034341, PMCID: PMC1169662, DOI: 10.1093/emboj/16.3.588.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBase SequenceChromosomesCloning, MolecularDNA, SatelliteElectrophoresis, Agar GelEvolution, MolecularGenetic MarkersHaplotypesHumansLinkage DisequilibriumMolecular Sequence DataPedigreePolymorphism, GeneticPolymorphism, Restriction Fragment LengthPrimatesRecombination, GeneticRepetitive Sequences, Nucleic AcidRNA, Small NuclearSequence AnalysisConceptsU2 tandem arrayTandem arraysConcerted evolutionIntrachromosomal homogenizationU2 snRNAInterchromosomal gene conversionHuman U2 snRNARepeat unitsGenetic exchangeU2 genesGene conversionChromosome lineagesIndependent assortmentFlanking markersDiverse panelGenesMicrosatellite polymorphismSnRNACT alleleSacISacI polymorphismPolymorphismAllelesChromatid exchangesPrimary driving force
1993
A new polymorphic marker (D10S97) tightly linked to the multiple endocrine neoplasia type 2A (MEN2A) locus
Lichter J, Wu J, Brooks-Wilson A, Difillipantonio M, Brewster S, Ward D, Goodfellow P, Kidd K. A new polymorphic marker (D10S97) tightly linked to the multiple endocrine neoplasia type 2A (MEN2A) locus. Human Genetics 1993, 90: 516-520. PMID: 8094065, DOI: 10.1007/bf00217451.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBase SequenceChromosome MappingChromosomes, FungalChromosomes, Human, Pair 10Cloning, MolecularCricetinaeDeoxyribonuclease EcoRIDNADNA ProbesFemaleGene FrequencyGene LibraryGenetic LinkageGenetic MarkersGenome, HumanHumansHybrid CellsIn Situ Hybridization, FluorescenceLod ScoreMaleMolecular Sequence DataMultiple Endocrine NeoplasiaPedigreePolymorphism, GeneticPolymorphism, Restriction Fragment LengthSequence Analysis, DNA
1992
Localization of the gene for MEN 2A.
Lichter J, Difilippantonio M, Wu J, Miller D, Ward D, Goodfellow P, Kidd K. Localization of the gene for MEN 2A. Henry Ford Hospital Medical Journal 1992, 40: 199-204. PMID: 1362405.Peer-Reviewed Original ResearchConceptsGene mapping techniquesYeast artificial chromosomesMapping panelPericentromeric regionArtificial chromosomesGenetic linkage studiesChromosome 10GenesSitu hybridizationLinkage studiesChromosomesMBMultiple endocrine neoplasia type 2A syndromeDNAHybridizationRegionConsistent orderSmall regionLocalizationFluorescenceMarkers
1990
Report of the DNA committee and catalogues of cloned and mapped genes and DNA polymorphisms (Part 1 of 14)
Williamson R, Bowcock A, Kidd K, Pearson P, Schmidtke J, Chan H, Chipperfield M, Cooper D, Hewitt J, Lewitter F, Maidak B, Quitt M, Ricciuti F, Track R, Tolley M, Trumper S, Walley A. Report of the DNA committee and catalogues of cloned and mapped genes and DNA polymorphisms (Part 1 of 14). Cytogenetic And Genome Research 1990, 55: 457-472. PMID: 2073845, DOI: 10.1159/000133027.Peer-Reviewed Original Research
1987
MSP RFLP for X-linked proteolipid protein gene (PLP) identified with either rat or human PLP cDNA clone
Wu J, Riordan J, Willard H, Milner R, Kidd K. MSP RFLP for X-linked proteolipid protein gene (PLP) identified with either rat or human PLP cDNA clone. Nucleic Acids Research 1987, 15: 1882-1882. PMID: 2434933, PMCID: PMC340598, DOI: 10.1093/nar/15.4.1882.Peer-Reviewed Original Research
1986
Linkage Analysis in a Family with Dominantly Inherited Torsion Dystonia: Exclusion of the Pro-Opiomelanocortin and Glutamic Acid Decarboxylase Genes and Other Chromosomal Regions Using DNA Polymorphisms
Breakefield X, Bressman S, Kramer P, Ozelius L, Moskowitz C, Tanzi R, Brin M, Hobbs W, Kaufman D, Tobin A, Kidd K, Fahn S, Gusella J. Linkage Analysis in a Family with Dominantly Inherited Torsion Dystonia: Exclusion of the Pro-Opiomelanocortin and Glutamic Acid Decarboxylase Genes and Other Chromosomal Regions Using DNA Polymorphisms. Journal Of Neurogenetics 1986, 3: 159-175. PMID: 3016220, DOI: 10.3109/01677068609106846.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedChildChild, PreschoolChromosome DeletionChromosome MappingCloning, MolecularDNADNA Restriction EnzymesDystonia Musculorum DeformansFemaleGenesGenes, DominantGenetic LinkageGlutamate DecarboxylaseHumansLymphocytesMaleMiddle AgedPedigreePolymorphism, GeneticPro-OpiomelanocortinConceptsLinkage analysisGlutamic acid decarboxylase geneRestriction fragment length polymorphismDecarboxylase geneDNA sequencesMode of inheritanceChromosomal regionsDNA polymorphismsFragment length polymorphismDefective geneLod score methodGenesDNA probesLength polymorphismLymphoblast linesInheritanceDisease statesAutosomal dominant modeGene penetranceSequenceFamilyPolymorphismGenomeAcid decarboxylaseRequisite assumptions
1985
An anonymous single copy X-chromosome clone, DXS79, from Xq26-Xq28, identifies a moderately frequent RFLP [HGM8 provisional no. DXS79]
Murphy P, Kidd J, Breg W, Ruddle F, Kidd K. An anonymous single copy X-chromosome clone, DXS79, from Xq26-Xq28, identifies a moderately frequent RFLP [HGM8 provisional no. DXS79]. Nucleic Acids Research 1985, 13: 3015-3015. PMID: 4000970, PMCID: PMC341211, DOI: 10.1093/nar/13.8.3015.Peer-Reviewed Original Research