1996
Conserved regulatory element involved in the early onset of Hoxb6 gene expression
Becker D, Jiang Z, Knödler P, Deinard A, Eid R, Kidd K, Shashikant C, Ruddle F, Schughart K. Conserved regulatory element involved in the early onset of Hoxb6 gene expression. Developmental Dynamics 1996, 205: 73-81. PMID: 8770553, DOI: 10.1002/(sici)1097-0177(199601)205:1<73::aid-aja7>3.0.co;2-2.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBase SequenceConserved SequenceDNADNA PrimersEmbryonic and Fetal DevelopmentEnhancer Elements, GeneticGene Expression Regulation, DevelopmentalGenes, HomeoboxGenes, RegulatorGenes, ReporterHomeodomain ProteinsHumansIn Situ HybridizationMesodermMiceMice, TransgenicMolecular Sequence DataSequence Homology, Nucleic AcidConceptsGene expressionPosterior lateral plate mesodermConserved regulatory elementsLateral plate mesodermReporter gene analysisSimilar enhancer activityHuman DNA sequencesBp DNA fragmentMammalian embryosMouse developmentPlate mesodermRegulatory elementsDNA sequencesEnhancer activityExpression patternsDNA fragmentsGene analysisEnhancerTransgenic miceExpressionInitial activationEarly stagesMesodermEmbryosTransgene
1995
Evidence for inter-generational instability in the CAG repeat in the MJD1 gene and for conserved haplotypes at flanking markers amongst Japanese and Caucasian subjects with Machado-Joseph disease
Takiyama Y, Igasrashi S, Rogaeva E, Endo K, Rogaev E, Tanaka H, Sherrington R, Sanpei K, Liang Y, Saito M, Tsuda T, Takano H, Ikeda M, Lin C, Chi H, Kennedy J, Lang A, Wherrett J, Segawa M, Nomura Y, Yuasa T, Weissenbach J, Yoshida M, Nishizawa M, Kidd K, Tsuji S, St George-Hyslop P. Evidence for inter-generational instability in the CAG repeat in the MJD1 gene and for conserved haplotypes at flanking markers amongst Japanese and Caucasian subjects with Machado-Joseph disease. Human Molecular Genetics 1995, 4: 1137-1146. PMID: 8528200, DOI: 10.1093/hmg/4.7.1137.Peer-Reviewed Original ResearchAge of OnsetAllelesAsian PeopleAtaxin-3Base SequenceConserved SequenceFemaleGenetics, PopulationHaplotypesHomozygoteHumansJapanMachado-Joseph DiseaseMaleMeiosisMolecular Sequence DataNerve Tissue ProteinsNuclear ProteinsPedigreePhenotypePolymorphism, GeneticProteinsRepetitive Sequences, Nucleic AcidRepressor ProteinsWhite People