1996
Early presentation of metastatic medullary carcinoma in multiple endocrine neoplasia, type IIA: Implications for therapy
Gill J, Reyes-Múgica M, Iyengar S, Kidd K, Touloukian R, Smith C, Keller M, Genel M. Early presentation of metastatic medullary carcinoma in multiple endocrine neoplasia, type IIA: Implications for therapy. The Journal Of Pediatrics 1996, 129: 459-464. PMID: 8804341, DOI: 10.1016/s0022-3476(96)70084-7.Peer-Reviewed Original ResearchConceptsMedullary thyroid carcinomaMultiple endocrine neoplasiaEndocrine neoplasiaThyroid carcinomaMultifocal medullary thyroid carcinomaMetastatic medullary carcinomaElevated calcitonin levelsC-cell hyperplasiaType IIaAge 1 yearYears of ageYears 8 monthsYears 11 monthsIIA patientsLymph nodesCalcitonin levelsProphylactic thyroidectomyMedullary carcinomaStimulation testEarly presentationPositive findingsCarcinomaThyroidectomyNeoplasiaAge
1993
Genomic and Yeast Artificial Chromosome Long-Range Regular Article Linking Six Loci in 10q11.2 and Spanning the Multiple Endocrine Neoplasia Type 2A (MEN2A) Region
Brooks-Wilson A, Lichter J, Ward D, Kidd K, Goodfellow P. Genomic and Yeast Artificial Chromosome Long-Range Regular Article Linking Six Loci in 10q11.2 and Spanning the Multiple Endocrine Neoplasia Type 2A (MEN2A) Region. Genomics 1993, 17: 611-617. PMID: 7902324, DOI: 10.1006/geno.1993.1380.Peer-Reviewed Original ResearchConceptsRestriction mappingIdentification of genesLong-range restriction mappingContig assemblyPhysical mapTumor-specific alterationsGenomic DNAYAC contigPhysical linkageCandidate intervalDistal lociLociProto-oncogeneD10S102GenesCandidate regionsRET proto-oncogeneFamilial medullary thyroid carcinomaType 2ARETD10S94Multiple endocrine neoplasia type 2AContigsGenomicsHereditary cancer
1990
The mutation for medullary thyroid carcinoma with parathyroid tumors (MTC with PTs) is closely linked to the centromeric region of chromosome 10.
Carson N, Wu J, Jackson C, Kidd K, Simpson N. The mutation for medullary thyroid carcinoma with parathyroid tumors (MTC with PTs) is closely linked to the centromeric region of chromosome 10. American Journal Of Human Genetics 1990, 47: 946-51. PMID: 1978560, PMCID: PMC1683917.Peer-Reviewed Original Research