2020
Validation of novel forensic DNA markers using multiplex microhaplotype sequencing
Gandotra N, Speed WC, Qin W, Tang Y, Pakstis AJ, Kidd KK, Scharfe C. Validation of novel forensic DNA markers using multiplex microhaplotype sequencing. Forensic Science International Genetics 2020, 47: 102275. PMID: 32305739, PMCID: PMC10131188, DOI: 10.1016/j.fsigen.2020.102275.Peer-Reviewed Original ResearchConceptsSingle nucleotide polymorphismsMH lociMultiplex sequencingNovel single nucleotide polymorphismsSmall DNA amountsSingle MiSeq runMultiple single nucleotide polymorphismsHigher effective numberBiogeographic variationDNA markersGenomic sequencesNovel lociGenome ProjectDNA amountMiSeq runDifferent world populationsNucleotide polymorphismsLociSequencingMicrohaplotypesEffective numberDiverse range
2001
Comparisons of Two Methods for Haplotype Reconstruction and Haplotype Frequency Estimation from Population Data
Zhang S, Pakstis A, Kidd K, Zhao H. Comparisons of Two Methods for Haplotype Reconstruction and Haplotype Frequency Estimation from Population Data. American Journal Of Human Genetics 2001, 69: 906-912. PMID: 11536083, PMCID: PMC1226079, DOI: 10.1086/323622.Peer-Reviewed Original Research
2000
The Accuracy of Statistical Methods for Estimation of Haplotype Frequencies: An Example from the CD4 Locus
Tishkoff S, Pakstis A, Ruano G, Kidd K. The Accuracy of Statistical Methods for Estimation of Haplotype Frequencies: An Example from the CD4 Locus. American Journal Of Human Genetics 2000, 67: 518-522. PMID: 10859209, PMCID: PMC1287198, DOI: 10.1086/303000.Peer-Reviewed Original Research
1999
On a Randomization Procedure in Linkage Analysis
Zhao H, Merikangas K, Kidd K. On a Randomization Procedure in Linkage Analysis. American Journal Of Human Genetics 1999, 65: 1449-1456. PMID: 10521312, PMCID: PMC1288298, DOI: 10.1086/302607.Peer-Reviewed Original ResearchConceptsEfficient simulation procedureObserved test statisticSimulation-based methodTheoretical resultsTest statisticNovel simulation methodSimulation methodReal dataSimulation procedureUninformative markersTheoretical workStatistical testsPedigree structureGenomewide significance levelRandomization procedureDiabetes dataStatisticsA more powerful method to evaluate p‐values in GENEHUNTER
Zhao H, Sheffield L, Pakstis A, Knauert M, Kidd K. A more powerful method to evaluate p‐values in GENEHUNTER. Genetic Epidemiology 1999, 17: s415-s420. PMID: 10597472, DOI: 10.1002/gepi.1370170770.Peer-Reviewed Original Research
1996
Dynamics of the haplotype frequencies in populations: study using the Monte Carlo method.
Grigorenko E, Shikanian A, Kidd D, Dorig R, Kidd K. Dynamics of the haplotype frequencies in populations: study using the Monte Carlo method. Genetika 1996, 32: 1705-13. PMID: 9102365.Peer-Reviewed Original ResearchConceptsNatural selectionEffective population sizeRandom genetic driftMonte Carlo methodHaplotype frequenciesGenetic driftRandom matingEvolutionary dynamicsCarlo methodPopulation sizeRecurrent mutationsMutation processHarmonic meanFrequency dynamicsDifferent populationsSimulation resultsExperimental dataDynamicsMatingPopulationMutationsHaplotypesAllelesColonizationNew World colonizationDNA Workbench: A Database Package to Manage Regional Physical Mapping
Nadkarni P, Cheung K, Castiglione C, Miller P, Kidd K. DNA Workbench: A Database Package to Manage Regional Physical Mapping. Journal Of Computational Biology 1996, 3: 319-329. PMID: 8811490, DOI: 10.1089/cmb.1996.3.319.Peer-Reviewed Original Research
1995
HAPLO: A Program Using the EM Algorithm to Estimate the Frequencies of Multi-site Haplotypes
Hawley M, Kidd K. HAPLO: A Program Using the EM Algorithm to Estimate the Frequencies of Multi-site Haplotypes. Journal Of Heredity 1995, 86: 409-411. PMID: 7560877, DOI: 10.1093/oxfordjournals.jhered.a111613.Peer-Reviewed Original Research
1994
Computer-assisted restriction mapping: an integrated approach to handling experimental uncertainty
Wright L, Lichter J, Reinitz J, Shifman M, Kidd K, Miller P. Computer-assisted restriction mapping: an integrated approach to handling experimental uncertainty. Bioinformatics 1994, 10: 435-442. PMID: 7804876, DOI: 10.1093/bioinformatics/10.4.435.Peer-Reviewed Original Research
1991
Parallelizing genetic linkage analysis: A case study for applying parallel computation in molecular biology
Miller P, Nadkarni P, Gelernter J, Carriero N, Pakstis A, Kidd K. Parallelizing genetic linkage analysis: A case study for applying parallel computation in molecular biology. Journal Of Biomedical Informatics 1991, 24: 234-248. PMID: 1868693, DOI: 10.1016/0010-4809(91)90046-y.Peer-Reviewed Original ResearchConceptsParallel computersSequential programsMachine-independent parallel programming languageParallel programming languageDifferent parallel machinesLengthy computation timeParallel programsProgramming languageAvailable processorsDifferent processorsParallel computationParallel machinesSequential versionParallel versionComputational loadComputation timePerformance benchmarksComputerProcessorsCase studyDifferent piecesIterative programsLINKMAPComputationParallel formsModeling uncertainty in a database for physical gene mapping data.
Miller P, Shifman M, Kidd K. Modeling uncertainty in a database for physical gene mapping data. AMIA Annual Symposium Proceedings 1991, 409-13. PMID: 1807633, PMCID: PMC2247564.Peer-Reviewed Original Research
1990
Segregation and Linkage Analyses of Tourette's Syndrome and Related Disorders
PAULS D, PAKSTIS A, KURLAN R, KIDD K, LECKMAN J, COHEN D, KIDD J, COMO P, SPARKES R. Segregation and Linkage Analyses of Tourette's Syndrome and Related Disorders. Journal Of The American Academy Of Child & Adolescent Psychiatry 1990, 29: 195-203. PMID: 2324061, DOI: 10.1097/00004583-199003000-00007.Peer-Reviewed Original Research
1986
Development of a map of chromosome 11p
Kramer P, Farrer L, Pakstis A, Kidd K. Development of a map of chromosome 11p. Genetic Epidemiology. Supplement 1986, 3: 153-158. PMID: 3471659, DOI: 10.1002/gepi.1370030724.Peer-Reviewed Original Research
1984
Utilizing automated methods to improve estimates of recurrence risk with linked genetic markers
Price R, Kidd K, Opitz J. Utilizing automated methods to improve estimates of recurrence risk with linked genetic markers. American Journal Of Medical Genetics 1984, 17: 621-625. PMID: 6585143, DOI: 10.1002/ajmg.1320170311.Peer-Reviewed Original ResearchGenetic analysis workshop II: Further consideration of segregation and linkage analyses in problem 3
Kramer P, Altmann D, Kidd K. Genetic analysis workshop II: Further consideration of segregation and linkage analyses in problem 3. Genetic Epidemiology 1984, 1: 189-193. PMID: 14971372, DOI: 10.1002/gepi.1370010213.Peer-Reviewed Original ResearchThe detection of major loci by segregation and linkage analysis: A simulation study
Goldin L, Cox N, Pauls D, Gershon E, Kidd K, Rao D. The detection of major loci by segregation and linkage analysis: A simulation study. Genetic Epidemiology 1984, 1: 285-296. PMID: 6599402, DOI: 10.1002/gepi.1370010307.Peer-Reviewed Original ResearchSegregation analyses of stuttering
Cox N, Kramer P, Kidd K, Rao D. Segregation analyses of stuttering. Genetic Epidemiology 1984, 1: 245-253. PMID: 6549563, DOI: 10.1002/gepi.1370010304.Peer-Reviewed Original ResearchConceptsFirst-degree relatives