2010
A Variant in a MicroRNA complementary site in the 3′ UTR of the KIT oncogene increases risk of acral melanoma
Godshalk SE, Paranjape T, Nallur S, Speed W, Chan E, Molinaro AM, Bacchiocchi A, Hoyt K, Tworkoski K, Stern DF, Sznol M, Ariyan S, Lazova R, Halaban R, Kidd KK, Weidhaas JB, Slack FJ. A Variant in a MicroRNA complementary site in the 3′ UTR of the KIT oncogene increases risk of acral melanoma. Oncogene 2010, 30: 1542-1550. PMID: 21119596, PMCID: PMC3069149, DOI: 10.1038/onc.2010.536.Peer-Reviewed Original ResearchConceptsMessenger RNAsComplementary sitesNovel genetic markersKIT oncogeneTarget genesRegulatory relationshipsUntranslated regionGenetic markersHeritable riskFunctional variantsGenetic variantsOncogeneMultifaceted roleProtein levelsProtein expressionVariant resultsComplementary sequencesReporter dataUTRMelanoma pathogenesisMiR-221KIT variantsSeed regionExpressionVariants
1987
Early Onset (Under Age 30 Years) and Panic Disorder as Markers for Etiologic Homogeneity in Major Depression
Price R, Kidd K, Weissman M. Early Onset (Under Age 30 Years) and Panic Disorder as Markers for Etiologic Homogeneity in Major Depression. JAMA Psychiatry 1987, 44: 434-440. PMID: 3472494, DOI: 10.1001/archpsyc.1987.01800170048008.Peer-Reviewed Original ResearchConceptsEarly onsetMajor depressionPanic disorderLate-onset depressionPrevalence of depressionElevation of riskFamilies of probandsYale Family StudyEtiologic homogeneityHigh riskPatterns of transmissionOlder age cohortsRestriction of analysisDepressionPopulation ratesFamily studiesProbandsOnsetDisordersAge cohortsRiskGenetic modelsSample sizeCohortPrevalence
1986
Gilles de la Tourette's Syndrome and Attention Deficit Disorder With Hyperactivity: Evidence Against a Genetic Relationship
Pauls D, Hurst C, Kruger S, Leckman J, Kidd K, Cohen D. Gilles de la Tourette's Syndrome and Attention Deficit Disorder With Hyperactivity: Evidence Against a Genetic Relationship. JAMA Psychiatry 1986, 43: 1177-1179. PMID: 3465279, DOI: 10.1001/archpsyc.1986.01800120063012.Peer-Reviewed Original ResearchFamily-Genetic Studies of Psychiatric Disorders: Developing Technologies
Weissman M, Merikangas K, John K, Wickramaratne P, Prusoff B, Kidd K. Family-Genetic Studies of Psychiatric Disorders: Developing Technologies. JAMA Psychiatry 1986, 43: 1104-1116. PMID: 3532996, DOI: 10.1001/archpsyc.1986.01800110090012.Peer-Reviewed Original ResearchConceptsPsychiatric disordersFamily genetic studiesMode of transmissionFuture genetic linkage studiesPsychiatric illnessChildhood manifestationsClinical practiceDiagnostic proceduresStudy designDisordersGenetic linkage studiesFamily studiesHomogeneous subgroupsLinkage studiesAdultsInformative familiesUnderstanding the Clinical Heterogeneity of Major Depression Using Family Data
Weissman M, Merikangas K, Priya W, Kidd K, Prusoff B, Leckman J, Pauls D. Understanding the Clinical Heterogeneity of Major Depression Using Family Data. JAMA Psychiatry 1986, 43: 430-434. PMID: 3964021, DOI: 10.1001/archpsyc.1986.01800050028003.Peer-Reviewed Original ResearchConceptsMajor depressionSymptom patternsHistory of hospitalizationClinical presentationClinical severityRecurrent depressionSecondary alcoholismClinical heterogeneitySuicidal ideationAnxiety disordersDepressionFamilial aggregationEarly ageDisordersCombination of criteriaAgeSubgroupsRiskOnsetPutative subgroupsHospitalizationRecurrence risks in an oligogenic threshold model: the effect of alterations in allele frequency
KENDLER K, KIDD K. Recurrence risks in an oligogenic threshold model: the effect of alterations in allele frequency. Annals Of Human Genetics 1986, 50: 83-91. PMID: 3426150, DOI: 10.1111/j.1469-1809.1986.tb01941.x.Peer-Reviewed Original Research
1984
Onset of Major Depression in Early Adulthood: Increased Familial Loading and Specificity
Weissman M, Wickramaratne P, Merikangas K, Leckman J, Prusoff B, Caruso K, Kidd K, Gammon G. Onset of Major Depression in Early Adulthood: Increased Familial Loading and Specificity. JAMA Psychiatry 1984, 41: 1136-1143. PMID: 6508504, DOI: 10.1001/archpsyc.1984.01790230022003.Peer-Reviewed Original ResearchConceptsAge of onsetMajor depressionNormal control subjectsRelatives of probandsFamilial loadingControl subjectsEarly-onset depressionFirst-degree relativesYears of ageHigh familial loadingHigh riskNormal subjectsSpecificity of transmissionEarly adulthoodDepressionProbandsAgeMore studiesFamily studiesYoung personOnsetLater ageHomogeneous disorderSubjectsInverse relationshipThe Risk of Tourette's Syndrome and Chronic Multiple Tics among Relatives of Tourette's Syndrome Patients Obtained by Direct Interview
PAULS D, KRUGER S, LECKMAN J, COHEN D, KIDD K. The Risk of Tourette's Syndrome and Chronic Multiple Tics among Relatives of Tourette's Syndrome Patients Obtained by Direct Interview. Journal Of The American Academy Of Child & Adolescent Psychiatry 1984, 23: 134-137. PMID: 6585415, DOI: 10.1097/00004583-198403000-00003.Peer-Reviewed Original ResearchUtilizing automated methods to improve estimates of recurrence risk with linked genetic markers
Price R, Kidd K, Opitz J. Utilizing automated methods to improve estimates of recurrence risk with linked genetic markers. American Journal Of Medical Genetics 1984, 17: 621-625. PMID: 6585143, DOI: 10.1002/ajmg.1320170311.Peer-Reviewed Original ResearchPsychiatric Disorders in the Relatives of Probands With Affective Disorders: The Yale University—National Institute of Mental Health Collaborative Study
Weissman M, Gershon E, Kidd K, Prusoff B, Leckman J, Dibble E, Hamovit J, Thompson W, Pauls D, Guroff J. Psychiatric Disorders in the Relatives of Probands With Affective Disorders: The Yale University—National Institute of Mental Health Collaborative Study. JAMA Psychiatry 1984, 41: 13-21. PMID: 6691780, DOI: 10.1001/archpsyc.1984.01790120015003.Peer-Reviewed Original ResearchConceptsRelatives of probandsMajor depressionPsychiatric disordersAffective disordersMental Health Collaborative StudyComparable diagnostic criteriaFirst-degree relativesComparability of ratesDiagnostic criteriaBipolar disorderDepressed probandsMost disordersDisordersProbandsFamily studiesCollaborative studyRelativesAmbulatoryIllnessPsychopathology in the Children (Ages 6–18) of Depressed and Normal Parents
WEISSMAN M, PRUSOFF B, GAMMON G, MERIKANGAS K, LECKMAN J, KIDD K. Psychopathology in the Children (Ages 6–18) of Depressed and Normal Parents. Journal Of The American Academy Of Child & Adolescent Psychiatry 1984, 23: 78-84. PMID: 6693680, DOI: 10.1097/00004583-198401000-00011.Peer-Reviewed Original ResearchConceptsDSM-III diagnosesFirst-degree relativesMajor depressionPsychiatric disordersProbands' first-degree relativesChildren of probandsCommon psychiatric disordersDirect interview studyFamily history studyClinical statusPsychiatric illnessNormal controlsDepressed probandsPsychological symptomsSuicidal behaviorEarly onsetDiagnosisDepressionSignificant predictorsProbandsAttention deficitsChildrenRiskEmotional problemsNormal parents
1982
Variability in Rates of Affective Disorders in Relatives of Depressed and Normal Probands
Weissman M, Kidd K, Prusoff B. Variability in Rates of Affective Disorders in Relatives of Depressed and Normal Probands. JAMA Psychiatry 1982, 39: 1397-1403. PMID: 7149900, DOI: 10.1001/archpsyc.1982.04290120033006.Peer-Reviewed Original ResearchComparison of the family history method to direct interview Factors affecting the diagnosis of depression
Orvaschel H, Thompson W, Belanger A, Prusoff B, Kidd K. Comparison of the family history method to direct interview Factors affecting the diagnosis of depression. Journal Of Affective Disorders 1982, 4: 49-59. PMID: 6461687, DOI: 10.1016/0165-0327(82)90019-2.Peer-Reviewed Original ResearchConceptsDiagnosis of depressionFamily history reportsEndogenous symptomsHistory reportsFirst-degree relativesSADS-L interviewsFamily history criteriaSymptoms of depressionAge of onsetFamily history methodIllness characteristicsPsychiatric statusSpecific symptomsSevere casesTreatment statusSymptomsHistory criteriaDepressionSubject characteristicsDiagnosis
1981
Familial patterns and possible modes of inheritance of primary affective disorders
Smeraldi E, Negri F, Heimbuch R, Kidd K. Familial patterns and possible modes of inheritance of primary affective disorders. Journal Of Affective Disorders 1981, 3: 173-182. PMID: 6454711, DOI: 10.1016/0165-0327(81)90042-2.Peer-Reviewed Original Research
1980
Penetrance estimates and recurrence risks for fibromuscular dysplasia
Gladstien K, Rushton A, Kidd K. Penetrance estimates and recurrence risks for fibromuscular dysplasia. Clinical Genetics 1980, 17: 115-116. PMID: 7363496, DOI: 10.1111/j.1399-0004.1980.tb00117.x.Peer-Reviewed Original Research
1979
Recurrence risks in schizophrenia: Are they model dependent?
Morton L, Kidd K, Matthysse S, Richards R. Recurrence risks in schizophrenia: Are they model dependent? Behavior Genetics 1979, 9: 389-406. PMID: 539966, DOI: 10.1007/bf01066977.Peer-Reviewed Original Research