1999
Global variation in the frequencies of functionally different catechol-O-methyltransferase alleles
Palmatier M, Kang A, Kidd K. Global variation in the frequencies of functionally different catechol-O-methyltransferase alleles. Biological Psychiatry 1999, 46: 557-567. PMID: 10459407, DOI: 10.1016/s0006-3223(99)00098-0.Peer-Reviewed Original ResearchMeSH KeywordsAllelesAnimalsCatechol O-MethyltransferaseCentral Nervous System DiseasesFemaleGene FrequencyGenetic LinkageGenetic MarkersHumansMaleMental DisordersPolymerase Chain ReactionPolymorphism, Restriction Fragment LengthPrimatesRacial GroupsReference ValuesConceptsRestriction site polymorphismsSingle nucleotide polymorphismsAllele frequenciesDifferent population frequenciesControl allele frequenciesEnzyme activity levelsAncestral alleleCandidate genesPopulation-based association studyAssociation studiesSite polymorphismFirst global surveyNucleotide polymorphismsAllelesEnzyme activityPopulation frequencyPolymorphismDifferent populationsCOMT enzyme activityActivity alleleLow-activity alleleGenesProteinGlobal variationPopulation
1998
Analyses of Cross Species Polymerase Chain Reaction Products to Infer the Ancestral State of Human Polymorphisms
Iyengar S, Seaman M, Deinard A, Rosenbaum H, Sirugo G, Castiglione C, Kidd J, Kidd K. Analyses of Cross Species Polymerase Chain Reaction Products to Infer the Ancestral State of Human Polymorphisms. Mitochondrial DNA Part A 1998, 8: 317-327. PMID: 10993602, DOI: 10.3109/10425179809034076.Peer-Reviewed Original ResearchConceptsSingle-strand conformational polymorphismSequence dataUntranslated regionHuman polymorphismsSingle ancestral allelePolymorphic allelesRestriction enzyme sitesAncestral stateExtant populationsGenomic regionsAncestral statusAncestral onesAncestral alleleHuman sequenceHuman allelesStrand conformational polymorphismPCR-RFLPsRestriction fragment length analysisPolymorphic sitesNumerous populationsEnzyme sitesAllelesSpeciesConformational polymorphismPolymerase chain reaction products
1997
Population genetics of a functional variant of the dopamine β‐hydroxylase gene (DBH)
Cubells J, Kobayashi K, Nagatsu T, Kidd K, Kidd J, Calafell F, Kranzler H, Ichinose H, Gelernter J. Population genetics of a functional variant of the dopamine β‐hydroxylase gene (DBH). American Journal Of Medical Genetics 1997, 74: 374-379. PMID: 9259372, DOI: 10.1002/(sici)1096-8628(19970725)74:4<374::aid-ajmg7>3.0.co;2-p.Peer-Reviewed Original ResearchConcerted evolution of the tandemly repeated genes encoding human U2 snRNA (the RNU2 locus) involves rapid intrachromosomal homogenization and rare interchromosomal gene conversion
Liao D, Pavelitz T, Kidd J, Kidd K, Weiner A. Concerted evolution of the tandemly repeated genes encoding human U2 snRNA (the RNU2 locus) involves rapid intrachromosomal homogenization and rare interchromosomal gene conversion. The EMBO Journal 1997, 16: 588-598. PMID: 9034341, PMCID: PMC1169662, DOI: 10.1093/emboj/16.3.588.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBase SequenceChromosomesCloning, MolecularDNA, SatelliteElectrophoresis, Agar GelEvolution, MolecularGenetic MarkersHaplotypesHumansLinkage DisequilibriumMolecular Sequence DataPedigreePolymorphism, GeneticPolymorphism, Restriction Fragment LengthPrimatesRecombination, GeneticRepetitive Sequences, Nucleic AcidRNA, Small NuclearSequence AnalysisConceptsU2 tandem arrayTandem arraysConcerted evolutionIntrachromosomal homogenizationU2 snRNAInterchromosomal gene conversionHuman U2 snRNARepeat unitsGenetic exchangeU2 genesGene conversionChromosome lineagesIndependent assortmentFlanking markersDiverse panelGenesMicrosatellite polymorphismSnRNACT alleleSacISacI polymorphismPolymorphismAllelesChromatid exchangesPrimary driving force
1996
Distribution and frequency of a polymorphicAlu insertion at the plasminogen activator locus in humans
Tishkoff S, Ruano G, Kidd J, Kidd K. Distribution and frequency of a polymorphicAlu insertion at the plasminogen activator locus in humans. Human Genetics 1996, 97: 759-764. PMID: 8641693, DOI: 10.1007/bf02346186.Peer-Reviewed Original ResearchMeSH KeywordsBase SequenceEvolution, MolecularGene FrequencyGenetic TestingGenetic VariationGenetics, PopulationHumansIntronsMolecular Sequence DataPolymorphism, Restriction Fragment LengthRacial GroupsRepetitive Sequences, Nucleic AcidTissue Plasminogen ActivatorConceptsPlasminogen activator geneHuman populationTissue plasminogen activator geneRestriction fragment length polymorphismActivator geneActivator locusInsertion eventsFragment length polymorphismPLAT locusHuman evolutionPolymerase chain reaction analysisChain reaction analysisLength polymorphismPresence/absenceAllele frequenciesAllelesLociModern humansDRD2 Haplotypes Containing the TaqI A1 Allele: Implications for Alcoholism Research
Kidd K, Pakstis A, Castiglione C, Kidd J, Speed W, Goldman D, Knowler W, Lu R, Bonne‐Tamir B. DRD2 Haplotypes Containing the TaqI A1 Allele: Implications for Alcoholism Research. Alcohol Clinical And Experimental Research 1996, 20: 697-705. PMID: 8800387, DOI: 10.1111/j.1530-0277.1996.tb01674.x.Peer-Reviewed Original ResearchMeSH KeywordsAlcoholismAllelesAnimalsChromosome MappingDeoxyribonucleases, Type II Site-SpecificEthnicityGene FrequencyGenetics, PopulationHaplotypesHumansPolymerase Chain ReactionPolymorphism, GeneticPolymorphism, Restriction Fragment LengthReceptors, Dopamine D2Repetitive Sequences, Nucleic AcidResearchConceptsGenetic variationAssociation studiesUnrelated control samplesDopamine D2 receptor locusDiversity of haplotypesShort tandem repeat polymorphismsDRD2 locusEvolutionary historyRestriction fragment length polymorphismPopulation geneticsPhylogenetic originFragment length polymorphismAncestral originReceptor locusHomologous regionsIntron 2LociAllelic systemHigher primatesHaplotypesTandem repeat polymorphismAllelesConsiderable diversityDRD2 haplotypesPolymorphism
1995
Assignment of the 5HT7 receptor gene (HTR7) to chromosome 10q and exclusion of genetic linkage with tourette syndrome
Gelernter J, Rao P, Pauls D, Hamblin M, Sibley D, Kidd K. Assignment of the 5HT7 receptor gene (HTR7) to chromosome 10q and exclusion of genetic linkage with tourette syndrome. Genomics 1995, 26: 207-209. PMID: 7601444, DOI: 10.1016/0888-7543(95)80202-w.Peer-Reviewed Original ResearchMeSH KeywordsBlotting, SouthernChromosome MappingChromosomes, Human, Pair 10GenesHumansLod ScorePolymorphism, Restriction Fragment LengthReceptors, SerotoninTourette SyndromeConceptsGenetic linkageSomatic cell hybridsInteresting candidate genesPairwise linkage analysisCell hybridsNovel serotonin receptorCandidate genesChromosome 10Linkage analysisSouthern blotGenesExtended pedigreesLOD scoreReceptor geneLociGenetic polymorphismsHTR7PolymorphismReceptorsLIPED computer programDNALinkageHybridizationNeuropsychiatric disordersPedigree
1994
Progress in a genome scan for linkage in schizophrenia in a large Swedish kindred
Barr C, Kennedy J, Pakstis A, Wetterberg L, Sjögren B, Bierut L, Wadelius C, Wahlström J, Martinsson T, Giuffra L, Gelernter J, Hallmayer J, Moises H, Kurth J, Cavalli‐Sforza L, Kidd K. Progress in a genome scan for linkage in schizophrenia in a large Swedish kindred. American Journal Of Medical Genetics 1994, 54: 51-58. PMID: 7909991, DOI: 10.1002/ajmg.1320540110.Peer-Reviewed Original Research
1993
Assignment of the norepinephrine transporter protein (NET1) locusto chromosome 16
Gelernter J, Kruger S, Pakstis A, Pacholczyk T, Sparkes R, Kidd K, Amara S. Assignment of the norepinephrine transporter protein (NET1) locusto chromosome 16. Genomics 1993, 18: 690-692. PMID: 7905857, DOI: 10.1016/s0888-7543(05)80375-1.Peer-Reviewed Original ResearchMeSH KeywordsCarrier ProteinsChromosome MappingChromosomes, Human, Pair 16Deoxyribonucleases, Type II Site-SpecificDNA, ComplementaryGenetic LinkageGenetic MarkersHumansNorepinephrineNorepinephrine Plasma Membrane Transport ProteinsPolymorphism, Restriction Fragment LengthRestriction MappingSymportersConceptsNorepinephrine transporter proteinSomatic cell hybrid panelCell hybrid panelHybrid panelHP locusCEPH familiesLarge multigenerational familyTransporter proteinsLinkage analysisChromosome 16Provisional assignmentLinkage dataLociMultigenerational familiesGenetic polymorphismsSite of actionPreliminary assignmentNet1FamilyProteinRFLPSitesPolymorphismPCRLocalizationNuclear DNA polymorphisms in a wild population of yellow baboons (Papio hamadryas cynocephalus) from Mikumi National Park, Tanzania
Rogers J, Kidd K. Nuclear DNA polymorphisms in a wild population of yellow baboons (Papio hamadryas cynocephalus) from Mikumi National Park, Tanzania. American Journal Of Biological Anthropology 1993, 90: 477-486. PMID: 8097371, DOI: 10.1002/ajpa.1330900407.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntithrombin IIIApolipoproteins BBeta-N-AcetylhexosaminidasesDNAHexosaminidase BPapioPolymorphism, GeneticPolymorphism, Restriction Fragment LengthReninTanzaniaVimentinA new polymorphic marker (D10S97) tightly linked to the multiple endocrine neoplasia type 2A (MEN2A) locus
Lichter J, Wu J, Brooks-Wilson A, Difillipantonio M, Brewster S, Ward D, Goodfellow P, Kidd K. A new polymorphic marker (D10S97) tightly linked to the multiple endocrine neoplasia type 2A (MEN2A) locus. Human Genetics 1993, 90: 516-520. PMID: 8094065, DOI: 10.1007/bf00217451.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBase SequenceChromosome MappingChromosomes, FungalChromosomes, Human, Pair 10Cloning, MolecularCricetinaeDeoxyribonuclease EcoRIDNADNA ProbesFemaleGene FrequencyGene LibraryGenetic LinkageGenetic MarkersGenome, HumanHumansHybrid CellsIn Situ Hybridization, FluorescenceLod ScoreMaleMolecular Sequence DataMultiple Endocrine NeoplasiaPedigreePolymorphism, GeneticPolymorphism, Restriction Fragment LengthSequence Analysis, DNA
1992
Human population genetic studies using hypervariable loci. I. Analysis of Assamese, Australian, Cambodian, Caucasian, Chinese and Melanesian populations.
Balazs I, Neuweiler J, Gunn P, Kidd J, Kidd K, Kuhl J, Mingjun L. Human population genetic studies using hypervariable loci. I. Analysis of Assamese, Australian, Cambodian, Caucasian, Chinese and Melanesian populations. Genetics 1992, 131: 191-198. PMID: 1350557, PMCID: PMC1204953, DOI: 10.1093/genetics/131.1.191.Peer-Reviewed Original ResearchTwo RFLPs near HOX2@INGFR at locus D17S444E
Kennedy J, Honer W, Kaufmann C, Martignetti J, Brosius J, Kidd K. Two RFLPs near HOX2@INGFR at locus D17S444E. Nucleic Acids Research 1992, 20: 1171-1171. PMID: 1372406, PMCID: PMC312148, DOI: 10.1093/nar/20.5.1171.Peer-Reviewed Original ResearchExclusion of Linkage Between the Serotonin2 Receptor and Schizophrenia in a Large Swedish Kindred
Hallmayer J, Kennedy J, Wetterberg L, Sjögren B, Kidd K, Cavalli-Sforza L. Exclusion of Linkage Between the Serotonin2 Receptor and Schizophrenia in a Large Swedish Kindred. JAMA Psychiatry 1992, 49: 216-219. PMID: 1348924, DOI: 10.1001/archpsyc.1992.01820030048006.Peer-Reviewed Original ResearchMeSH KeywordsChromosomes, Human, Pair 13DNA ProbesFemaleGenetic LinkageHumansLod ScoreMaleMiddle AgedPolymorphism, Restriction Fragment LengthReceptors, SerotoninSchizophreniaSwedenPresymptomatic testing using DNA markers for individuals at risk for familial multiple endocrine neoplasia 2A
Lichter J, Wu J, Genel M, Flynn S, Pakstis A, Kidd J, Kidd K. Presymptomatic testing using DNA markers for individuals at risk for familial multiple endocrine neoplasia 2A. The Journal Of Clinical Endocrinology & Metabolism 1992, 74: 368-373. PMID: 1346145, DOI: 10.1210/jcem.74.2.1346145.Peer-Reviewed Original Research
1991
Studies of three Amerindian populations using nuclear DNA polymorphisms.
Kidd J, Black F, Weiss K, Balazs I, Kidd K. Studies of three Amerindian populations using nuclear DNA polymorphisms. Human Biology 1991, 63: 775-94. PMID: 1683642.Peer-Reviewed Original ResearchMeSH KeywordsAllelesBrazilChromosome MappingDNAGene FrequencyHeterozygoteHumansIndians, North AmericanIndians, South AmericanMexicoPolymorphism, GeneticPolymorphism, Restriction Fragment LengthPopulationA Hindi RFLP In the human D4 dopamine receptor locus (DRD4)
Kennedy J, Sidenberg D, Van Tol H, Kidd K. A Hindi RFLP In the human D4 dopamine receptor locus (DRD4). Nucleic Acids Research 1991, 19: 5801-5801. PMID: 1682888, PMCID: PMC329013, DOI: 10.1093/nar/19.20.5801.Peer-Reviewed Original ResearchChromosomes, Human, Pair 11Deoxyribonucleases, Type II Site-SpecificGene FrequencyHumansPolymorphism, Restriction Fragment LengthReceptors, DopamineReceptors, Dopamine D2Receptors, Dopamine D4Two RFLPs at the HOX2G locus
Ogura T, Castiglione C, Pakstis A, Kidd K. Two RFLPs at the HOX2G locus. Nucleic Acids Research 1991, 19: 1716-1716. PMID: 1674132, PMCID: PMC333946, DOI: 10.1093/nar/19.7.1716-a.Peer-Reviewed Original ResearchAllelesChromosome MappingChromosomes, Human, Pair 17DNA ProbesHumansPolymorphism, Restriction Fragment LengthAn Mspl polymorphism for the HOX2F gene
Ogura T, Castiglione C, Pakstis A, Kidd K. An Mspl polymorphism for the HOX2F gene. Nucleic Acids Research 1991, 19: 1716-1716. PMID: 1709280, PMCID: PMC333945, DOI: 10.1093/nar/19.7.1716.Peer-Reviewed Original ResearchAllelesChromosome MappingChromosomes, Human, Pair 17Deoxyribonuclease HpaIIDeoxyribonucleases, Type II Site-SpecificDNA ProbesGenes, HomeoboxHumansPolymorphism, Restriction Fragment Length
1990
The mutation for medullary thyroid carcinoma with parathyroid tumors (MTC with PTs) is closely linked to the centromeric region of chromosome 10.
Carson N, Wu J, Jackson C, Kidd K, Simpson N. The mutation for medullary thyroid carcinoma with parathyroid tumors (MTC with PTs) is closely linked to the centromeric region of chromosome 10. American Journal Of Human Genetics 1990, 47: 946-51. PMID: 1978560, PMCID: PMC1683917.Peer-Reviewed Original Research