1998
Repeat Expansion–Detection Analysis of Telomeric Uninterrupted (TTAGGG) n Arrays
Sirugo G, Kidd K. Repeat Expansion–Detection Analysis of Telomeric Uninterrupted (TTAGGG) n Arrays. American Journal Of Human Genetics 1998, 63: 648-651. PMID: 9683592, PMCID: PMC1377302, DOI: 10.1086/301961.Peer-Reviewed Original ResearchAnimalsArtifactsBase SequenceCell LineDNAGenetic TechniquesHumansPolymerase Chain ReactionRepetitive Sequences, Nucleic AcidTelomereTemplates, Genetic
1997
Editorial: Can we find genes for schizophrenia?
Kidd K. Editorial: Can we find genes for schizophrenia? American Journal Of Medical Genetics 1997, 74: 104-111. PMID: 9034016, DOI: 10.1002/(sici)1096-8628(19970221)74:1<104::aid-ajmg21>3.0.co;2-u.Peer-Reviewed Original ResearchConcerted evolution of the tandemly repeated genes encoding human U2 snRNA (the RNU2 locus) involves rapid intrachromosomal homogenization and rare interchromosomal gene conversion
Liao D, Pavelitz T, Kidd J, Kidd K, Weiner A. Concerted evolution of the tandemly repeated genes encoding human U2 snRNA (the RNU2 locus) involves rapid intrachromosomal homogenization and rare interchromosomal gene conversion. The EMBO Journal 1997, 16: 588-598. PMID: 9034341, PMCID: PMC1169662, DOI: 10.1093/emboj/16.3.588.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBase SequenceChromosomesCloning, MolecularDNA, SatelliteElectrophoresis, Agar GelEvolution, MolecularGenetic MarkersHaplotypesHumansLinkage DisequilibriumMolecular Sequence DataPedigreePolymorphism, GeneticPolymorphism, Restriction Fragment LengthPrimatesRecombination, GeneticRepetitive Sequences, Nucleic AcidRNA, Small NuclearSequence AnalysisConceptsU2 tandem arrayTandem arraysConcerted evolutionIntrachromosomal homogenizationU2 snRNAInterchromosomal gene conversionHuman U2 snRNARepeat unitsGenetic exchangeU2 genesGene conversionChromosome lineagesIndependent assortmentFlanking markersDiverse panelGenesMicrosatellite polymorphismSnRNACT alleleSacISacI polymorphismPolymorphismAllelesChromatid exchangesPrimary driving force
1996
Molecular Haplotyping of Genetic Markers 10 kb Apart by Allele-Specific Long-Range PCR
Michalatos-Beloin S, Tishkoff S, Bentley K, Kidd K, Ruano G. Molecular Haplotyping of Genetic Markers 10 kb Apart by Allele-Specific Long-Range PCR. Nucleic Acids Research 1996, 24: 4841-4843. PMID: 8972876, PMCID: PMC146303, DOI: 10.1093/nar/24.23.4841.Peer-Reviewed Original ResearchMeSH KeywordsAllelesCD4 AntigensGene DeletionGenetic LinkageGenetic MarkersGenotypeHaplotypesHumansPolymerase Chain ReactionRepetitive Sequences, Nucleic AcidConceptsMolecular haplotypingClassical Mendelian analysisMapping disease genesCD4 locusMolecular haplotypesDisease genesLong-range PCRGenomic samplesFounder effectPolymorphic markersMendelian analysisUnrelated individualsHaplotypingAlu deletionKbRange PCRHaplotypesDiversity researchPopulation samplingPCRChromosomesGenesRepeatsLociDeletionDistribution and frequency of a polymorphicAlu insertion at the plasminogen activator locus in humans
Tishkoff S, Ruano G, Kidd J, Kidd K. Distribution and frequency of a polymorphicAlu insertion at the plasminogen activator locus in humans. Human Genetics 1996, 97: 759-764. PMID: 8641693, DOI: 10.1007/bf02346186.Peer-Reviewed Original ResearchConceptsPlasminogen activator geneHuman populationTissue plasminogen activator geneRestriction fragment length polymorphismActivator geneActivator locusInsertion eventsFragment length polymorphismPLAT locusHuman evolutionPolymerase chain reaction analysisChain reaction analysisLength polymorphismPresence/absenceAllele frequenciesAllelesLociModern humansDRD2 Haplotypes Containing the TaqI A1 Allele: Implications for Alcoholism Research
Kidd K, Pakstis A, Castiglione C, Kidd J, Speed W, Goldman D, Knowler W, Lu R, Bonne‐Tamir B. DRD2 Haplotypes Containing the TaqI A1 Allele: Implications for Alcoholism Research. Alcohol Clinical And Experimental Research 1996, 20: 697-705. PMID: 8800387, DOI: 10.1111/j.1530-0277.1996.tb01674.x.Peer-Reviewed Original ResearchMeSH KeywordsAlcoholismAllelesAnimalsChromosome MappingDeoxyribonucleases, Type II Site-SpecificEthnicityGene FrequencyGenetics, PopulationHaplotypesHumansPolymerase Chain ReactionPolymorphism, GeneticPolymorphism, Restriction Fragment LengthReceptors, Dopamine D2Repetitive Sequences, Nucleic AcidResearchConceptsGenetic variationAssociation studiesUnrelated control samplesDopamine D2 receptor locusDiversity of haplotypesShort tandem repeat polymorphismsDRD2 locusEvolutionary historyRestriction fragment length polymorphismPopulation geneticsPhylogenetic originFragment length polymorphismAncestral originReceptor locusHomologous regionsIntron 2LociAllelic systemHigher primatesHaplotypesTandem repeat polymorphismAllelesConsiderable diversityDRD2 haplotypesPolymorphismThe world-wide distribution of allele frequencies at the human dopamine D4 receptor locus
Chang F, Kidd J, Livak K, Pakstis A, Kidd K. The world-wide distribution of allele frequencies at the human dopamine D4 receptor locus. Human Genetics 1996, 98: 91-101. PMID: 8682515, DOI: 10.1007/s004390050166.Peer-Reviewed Original ResearchMeSH KeywordsAfricaAllelesAsiaEuropeEvolution, MolecularExonsGene FrequencyHumansMiddle EastNorth AmericaPacific OceanPolymorphism, GeneticReceptors, Dopamine D2Receptors, Dopamine D4Repetitive Sequences, Nucleic AcidSouth AmericaConceptsImperfect tandem repeatsAllele frequenciesDifferent populationsActual allele frequenciesDopamine D4 receptor locusSelective forcesEvolutionary significanceWorld-wide distributionAssociation studiesReceptor locusTandem repeatsThird exonBase pairsAmino acidsFunctional relevanceRepeatsReceptor geneAllelesLociModern humansPolymorphismD4 receptor geneDopamine D4 receptor geneRepeat polymorphismExonsGlobal Patterns of Linkage Disequilibrium at the CD4 Locus and Modern Human Origins
Tishkoff S, Dietzsch E, Speed W, Pakstis A, Kidd J, Cheung K, Bonné-Tamir B, Santachiara-Benerecetti A, Moral P, Krings M, Pääbo S, Watson E, Risch N, Jenkins T, Kidd K. Global Patterns of Linkage Disequilibrium at the CD4 Locus and Modern Human Origins. Science 1996, 271: 1380-1387. PMID: 8596909, DOI: 10.1126/science.271.5254.1380.Peer-Reviewed Original ResearchNo association between alcoholism and multiple polymorphisms at the dopamine D2 receptor gene (DRD2) in three distinct taiwanese populations
Lu R, Ko H, Chang F, Castiglione C, Schoolfield G, Pakstis A, Kidd J, Kidd K. No association between alcoholism and multiple polymorphisms at the dopamine D2 receptor gene (DRD2) in three distinct taiwanese populations. Biological Psychiatry 1996, 39: 419-429. PMID: 8679787, DOI: 10.1016/0006-3223(95)00182-4.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAlcoholismAllelesEthnicityGenetics, PopulationGenotypeHaplotypesHumansLinkage DisequilibriumMaleMiddle AgedModels, GeneticPolymorphism, GeneticReceptors, Dopamine D2Repetitive Sequences, Nucleic AcidTaiwan
1995
Evidence for inter-generational instability in the CAG repeat in the MJD1 gene and for conserved haplotypes at flanking markers amongst Japanese and Caucasian subjects with Machado-Joseph disease
Takiyama Y, Igasrashi S, Rogaeva E, Endo K, Rogaev E, Tanaka H, Sherrington R, Sanpei K, Liang Y, Saito M, Tsuda T, Takano H, Ikeda M, Lin C, Chi H, Kennedy J, Lang A, Wherrett J, Segawa M, Nomura Y, Yuasa T, Weissenbach J, Yoshida M, Nishizawa M, Kidd K, Tsuji S, St George-Hyslop P. Evidence for inter-generational instability in the CAG repeat in the MJD1 gene and for conserved haplotypes at flanking markers amongst Japanese and Caucasian subjects with Machado-Joseph disease. Human Molecular Genetics 1995, 4: 1137-1146. PMID: 8528200, DOI: 10.1093/hmg/4.7.1137.Peer-Reviewed Original ResearchAge of OnsetAllelesAsian PeopleAtaxin-3Base SequenceConserved SequenceFemaleGenetics, PopulationHaplotypesHomozygoteHumansJapanMachado-Joseph DiseaseMaleMeiosisMolecular Sequence DataNerve Tissue ProteinsNuclear ProteinsPedigreePhenotypePolymorphism, GeneticProteinsRepetitive Sequences, Nucleic AcidRepressor ProteinsWhite People
1994
Progress in a genome scan for linkage in schizophrenia in a large Swedish kindred
Barr C, Kennedy J, Pakstis A, Wetterberg L, Sjögren B, Bierut L, Wadelius C, Wahlström J, Martinsson T, Giuffra L, Gelernter J, Hallmayer J, Moises H, Kurth J, Cavalli‐Sforza L, Kidd K. Progress in a genome scan for linkage in schizophrenia in a large Swedish kindred. American Journal Of Medical Genetics 1994, 54: 51-58. PMID: 7909991, DOI: 10.1002/ajmg.1320540110.Peer-Reviewed Original Research
1993
A hypervariable segment in the human dopamine receptor D4 (DRD4) gene
Lichter J, Barr C, Kennedy J, Van Tol H, Kidd K, Livak K. A hypervariable segment in the human dopamine receptor D4 (DRD4) gene. Human Molecular Genetics 1993, 2: 767-773. PMID: 8353495, DOI: 10.1093/hmg/2.6.767.Peer-Reviewed Original ResearchConceptsHuman dopamine receptor D4 geneAmino acid sequenceThird cytoplasmic loopNumber of repeatsPutative third cytoplasmic loopFunctional proteinsCytoplasmic loopAcid sequenceRepeat regionDifferent repeatsHypervariable segmentDifferent haplotypesRepeatsDopamine receptor D4 geneUnrelated chromosomesNovel polymorphismsD4 geneGenesProteinHuman dopamine D4 receptorPolymorphic variantsSequencePolymorphismChromosomesReceptors
1992
Human population genetic studies using hypervariable loci. I. Analysis of Assamese, Australian, Cambodian, Caucasian, Chinese and Melanesian populations.
Balazs I, Neuweiler J, Gunn P, Kidd J, Kidd K, Kuhl J, Mingjun L. Human population genetic studies using hypervariable loci. I. Analysis of Assamese, Australian, Cambodian, Caucasian, Chinese and Melanesian populations. Genetics 1992, 131: 191-198. PMID: 1350557, PMCID: PMC1204953, DOI: 10.1093/genetics/131.1.191.Peer-Reviewed Original ResearchA dinucleotide repeat polymorphism at the HOX2B locus
Deinard A, Ruano G, Kidd K. A dinucleotide repeat polymorphism at the HOX2B locus. Nucleic Acids Research 1992, 20: 1171-1171. PMID: 1347934, PMCID: PMC312149, DOI: 10.1093/nar/20.5.1171-a.Peer-Reviewed Original Research
1991
Progress towards completing the human linkage map
Kidd K. Progress towards completing the human linkage map. Current Opinion In Genetics & Development 1991, 1: 99-104. PMID: 1840885, DOI: 10.1016/0959-437x(91)80049-r.Peer-Reviewed Original ResearchMeSH KeywordsAllelesChromosome MappingGenetic LinkageGenetic MarkersHuman Genome ProjectHumansPolymerase Chain ReactionPolymorphism, GeneticRepetitive Sequences, Nucleic Acid
1990
Strong linkage disequilibrium between the XY274 polymorphism and the pseudoautosomal boundary.
Ellis N, Kidd J, Goodfellow P, Kidd K, Goodfellow P. Strong linkage disequilibrium between the XY274 polymorphism and the pseudoautosomal boundary. American Journal Of Human Genetics 1990, 46: 950-5. PMID: 2339693, PMCID: PMC1683589.Peer-Reviewed Original ResearchExtensive sequence polymorphisms associated with chromosome 10 alpha satellite DNA and its close linkage to markers from the pericentromeric region
Wu J, Kidd K. Extensive sequence polymorphisms associated with chromosome 10 alpha satellite DNA and its close linkage to markers from the pericentromeric region. Human Genetics 1990, 84: 279-282. PMID: 1968036, DOI: 10.1007/bf00200575.Peer-Reviewed Original ResearchMeSH KeywordsChromosomes, Human, Pair 10DNA, SatelliteGenetic MarkersHumansPolymorphism, Restriction Fragment LengthRepetitive Sequences, Nucleic AcidRestriction MappingConceptsAlpha satellite DNAExtensive sequence polymorphismSatellite DNAPericentromeric regionSequence polymorphismsExcellent genetic markerCentromeric regionsDNA markersGenetic markersEnzyme PstILOD scoreClose linkagePositive lod scoresLinkage studiesDNAType 2AIndependent supportPolymorphismCentromeresMorphsMarkersRBP3LociDistance relationshipsEcoRV