2013
Haplotype structure and positive selection at TLR1
Heffelfinger C, Pakstis AJ, Speed WC, Clark AP, Haigh E, Fang R, Furtado MR, Kidd KK, Snyder MP. Haplotype structure and positive selection at TLR1. European Journal Of Human Genetics 2013, 22: 551-557. PMID: 24002163, PMCID: PMC3953919, DOI: 10.1038/ejhg.2013.194.Peer-Reviewed Original ResearchConceptsToll-like receptor 2Toll-like receptor 1Missense variantsInnate immune systemReduced riskMedical conditionsReceptor 2Immune systemReceptor 1Cell surface receptorsSepsisSubsequent activationTLR1Surface receptorsBacterial lipoproteinsLeprosySurface traffickingDiseaseHuman healthRiskHealthMultiple functional allelesRs5743618TuberculosisLipoprotein
1992
Two RFLPs near HOX2@INGFR at locus D17S444E
Kennedy J, Honer W, Kaufmann C, Martignetti J, Brosius J, Kidd K. Two RFLPs near HOX2@INGFR at locus D17S444E. Nucleic Acids Research 1992, 20: 1171-1171. PMID: 1372406, PMCID: PMC312148, DOI: 10.1093/nar/20.5.1171.Peer-Reviewed Original Research
1986
DNA polymorphisms for the nerve growth factor receptor gene exclude its role in familial dysautonomia.
Breakefield X, Ozelius L, Bothwell M, Chao M, Axelrod F, Kramer P, Kidd K, Lanahan A, Johnson D, Ross A. DNA polymorphisms for the nerve growth factor receptor gene exclude its role in familial dysautonomia. Molecular Biology & Medicine 1986, 3: 483-94. PMID: 2886891.Peer-Reviewed Original ResearchConceptsNerve growth factor receptor geneGrowth factor receptor geneFactor receptor geneReceptor geneExcellent genetic markerAshkenazic Jewish populationPolymorphic restriction sitesDNA polymorphismsFamilial dysautonomiaGenetic markersBeta subunitLinkage analysisGenesRestriction sitesChromosome 17qAutosomal recessive modeAllelesPossible roleRecessive modeAffected individualsNeuronal factorsPolymorphismNGF actionCentimorgansMore members