2011
An Application of the Elastic Net for an Endophenotype Analysis
Palejev D, Hwang W, Landi N, Eastman M, Frost SJ, Fulbright RK, Kidd JR, Kidd KK, Mason GF, Mencl WE, Yrigollen C, Pugh KR, Grigorenko EL. An Application of the Elastic Net for an Endophenotype Analysis. Behavior Genetics 2011, 41: 120-124. PMID: 21229297, PMCID: PMC3613288, DOI: 10.1007/s10519-011-9443-8.Peer-Reviewed Original Research
2006
Sub‐Saharan African coding sequence variation and haplotype diversity at the NAT2 gene
Patin E, Harmant C, Kidd K, Kidd J, Froment A, Mehdi S, Sica L, Heyer E, Quintana‐Murci L. Sub‐Saharan African coding sequence variation and haplotype diversity at the NAT2 gene. Human Mutation 2006, 27: 720-720. PMID: 16786516, DOI: 10.1002/humu.9438.Peer-Reviewed Original ResearchConceptsNon-synonymous mutationsNovel non-synonymous mutationsEvolutionary conservationDetailed genetic characterizationIndividuals/populationsHaplotype diversityAgriculturalist populationsSequence variationProtein activityAfrican populationsWestern PygmiesAfrican haplotypesGenetic characterizationUnknown functional effectsGenesFunctional effectsNAT2 geneHaplotype frequenciesSub-Saharan African populationsMutationsChromosomesDamaging effectsLociPopulationProtein
2000
Sequence variability and candidate gene analysis in complex disease: association of µ opioid receptor gene variation with substance dependence
Hoehe M, Köpke K, Wendel B, Rohde K, Flachmeier C, Kidd K, Berrettini W, Church G. Sequence variability and candidate gene analysis in complex disease: association of µ opioid receptor gene variation with substance dependence. Human Molecular Genetics 2000, 9: 2895-2908. PMID: 11092766, DOI: 10.1093/hmg/9.19.2895.Peer-Reviewed Original ResearchConceptsComplex genotype-phenotype relationshipsGenotype-phenotype relationshipsCandidate genesSequence variabilitySequence variantsGene sequence informationDNA sequence variationCandidate gene analysisSpecific sequence variantsPrime candidate geneCombination of variantsSequence comparisonSequence variationSequence informationHuman mu-opioid receptor geneDifferent haplotypesGene analysisGenesComplex diseasesReceptor geneOpioid receptor geneHaplotypesGene variationMultiple individualsModel system
1999
A paradigm for finding genes for a complex human trait: Polycystic ovary syndrome and follistatin
Odunsi K, Kidd K. A paradigm for finding genes for a complex human trait: Polycystic ovary syndrome and follistatin. Proceedings Of The National Academy Of Sciences Of The United States Of America 1999, 96: 8315-8317. PMID: 10411866, PMCID: PMC33617, DOI: 10.1073/pnas.96.15.8315.Peer-Reviewed Original Research
1997
Population genetics of a functional variant of the dopamine β‐hydroxylase gene (DBH)
Cubells J, Kobayashi K, Nagatsu T, Kidd K, Kidd J, Calafell F, Kranzler H, Ichinose H, Gelernter J. Population genetics of a functional variant of the dopamine β‐hydroxylase gene (DBH). American Journal Of Medical Genetics 1997, 74: 374-379. PMID: 9259372, DOI: 10.1002/(sici)1096-8628(19970725)74:4<374::aid-ajmg7>3.0.co;2-p.Peer-Reviewed Original ResearchHomozygosity by descent for a rare mutation in the myophosphorylase gene is associated with variable phenotypes in a Druze family with McArdle disease.
Iyengar S, Kalinsky H, Weiss S, Korostishevsky M, Sadeh M, Zhao Y, Kidd K, Bonne-Tamir B. Homozygosity by descent for a rare mutation in the myophosphorylase gene is associated with variable phenotypes in a Druze family with McArdle disease. Journal Of Medical Genetics 1997, 34: 391. PMID: 9152836, PMCID: PMC1050946, DOI: 10.1136/jmg.34.5.391.Peer-Reviewed Original Research
1996
PhenoDB: An Integrated Client/Server Database for Linkage and Population Genetics
Cheung K, Nadkarni P, Silverstein S, Kidd J, Pakstis A, Miller P, Kidd K. PhenoDB: An Integrated Client/Server Database for Linkage and Population Genetics. Journal Of Biomedical Informatics 1996, 29: 327-337. PMID: 8812078, DOI: 10.1006/cbmr.1996.0024.Peer-Reviewed Original ResearchMeSH KeywordsAllelesComputer Communication NetworksComputer GraphicsComputer SystemsData Interpretation, StatisticalDatabase Management SystemsGene FrequencyGenetic LinkageGenetic MarkersGenetics, PopulationHumansInformation Storage and RetrievalInformation SystemsPedigreePhenotypeUser-Computer InterfaceConceptsClient/server databaseClient/server architectureData management tasksData analysis tasksUse graphical interfaceServer architectureDatabase applicationsComplex adServer databaseInteractive validationAnalysis tasksGraphical interfaceFile formatManagement tasksLarge datasetsPhenoDBMultipoint linkageGeneric formatHardy-Weinberg ratiosData entryEfficient managementProject managementGenetic marker dataPopulation geneticsTask
1995
HAPLO: A Program Using the EM Algorithm to Estimate the Frequencies of Multi-site Haplotypes
Hawley M, Kidd K. HAPLO: A Program Using the EM Algorithm to Estimate the Frequencies of Multi-site Haplotypes. Journal Of Heredity 1995, 86: 409-411. PMID: 7560877, DOI: 10.1093/oxfordjournals.jhered.a111613.Peer-Reviewed Original ResearchEvidence for inter-generational instability in the CAG repeat in the MJD1 gene and for conserved haplotypes at flanking markers amongst Japanese and Caucasian subjects with Machado-Joseph disease
Takiyama Y, Igasrashi S, Rogaeva E, Endo K, Rogaev E, Tanaka H, Sherrington R, Sanpei K, Liang Y, Saito M, Tsuda T, Takano H, Ikeda M, Lin C, Chi H, Kennedy J, Lang A, Wherrett J, Segawa M, Nomura Y, Yuasa T, Weissenbach J, Yoshida M, Nishizawa M, Kidd K, Tsuji S, St George-Hyslop P. Evidence for inter-generational instability in the CAG repeat in the MJD1 gene and for conserved haplotypes at flanking markers amongst Japanese and Caucasian subjects with Machado-Joseph disease. Human Molecular Genetics 1995, 4: 1137-1146. PMID: 8528200, DOI: 10.1093/hmg/4.7.1137.Peer-Reviewed Original ResearchAge of OnsetAllelesAsian PeopleAtaxin-3Base SequenceConserved SequenceFemaleGenetics, PopulationHaplotypesHomozygoteHumansJapanMachado-Joseph DiseaseMaleMeiosisMolecular Sequence DataNerve Tissue ProteinsNuclear ProteinsPedigreePhenotypePolymorphism, GeneticProteinsRepetitive Sequences, Nucleic AcidRepressor ProteinsWhite People
1990
The mutation for medullary thyroid carcinoma with parathyroid tumors (MTC with PTs) is closely linked to the centromeric region of chromosome 10.
Carson N, Wu J, Jackson C, Kidd K, Simpson N. The mutation for medullary thyroid carcinoma with parathyroid tumors (MTC with PTs) is closely linked to the centromeric region of chromosome 10. American Journal Of Human Genetics 1990, 47: 946-51. PMID: 1978560, PMCID: PMC1683917.Peer-Reviewed Original ResearchThe locus for the medium-chain acyl-CoA dehydrogenase gene on chromosome 1 is highly polymorphic
Kidd J, Matsubara Y, Castiglione C, Tanaka K, Kidd K. The locus for the medium-chain acyl-CoA dehydrogenase gene on chromosome 1 is highly polymorphic. Genomics 1990, 6: 89-93. PMID: 1968047, DOI: 10.1016/0888-7543(90)90451-y.Peer-Reviewed Original ResearchConceptsRestriction fragment length polymorphismMedium-chain acyl-CoA dehydrogenase (MCAD) geneAcyl-CoA dehydrogenase geneSomatic cell studiesMedium-chain acyl-CoA dehydrogenaseSignificant linkage disequilibriumAcyl-CoA dehydrogenaseLinkage mappingDehydrogenase geneRegional assignmentChromosome 1Fragment length polymorphismGenetic studiesLinkage analysisLinkage disequilibriumSitu hybridizationLength polymorphismLinkage studiesPGM1Clinical genetic studiesACADMGenesLociCell localizationRFLP systems
1987
Study of 47 DNA markers in five populations from four continents.
Bowcock A, Bucci C, Hebert J, Kidd J, Kidd K, Friedlaender J, Cavalli-Sforza L. Study of 47 DNA markers in five populations from four continents. Gene Geography 1987, 1: 47-64. PMID: 2908691.Peer-Reviewed Original Research
1986
Linkage Analyses of Multiple Endocrine Neoplasia, Type 2 (MEN-2) with 23 Classical Genetic Polymorphisms
Kruger S, Gertner J, Sparkes R, Haedt L, Crist M, Sparkes M, Genel M, Kidd K. Linkage Analyses of Multiple Endocrine Neoplasia, Type 2 (MEN-2) with 23 Classical Genetic Polymorphisms. Human Heredity 1986, 36: 6-11. PMID: 2868987, DOI: 10.1159/000153592.Peer-Reviewed Original ResearchClose linkage of MT2P1 with GC on chromosome 4
Pakstis A, Kidd J, Castiglione C, Sparkes R, Kidd K. Close linkage of MT2P1 with GC on chromosome 4. Cytogenetic And Genome Research 1986, 41: 189-190. PMID: 3956270, DOI: 10.1159/000132226.Peer-Reviewed Original Research
1985
Multiple threshold models for the affective disorders: The Yale-NIMH collaborative family study
Price R, Kidd K, Pauls D, Gershon E, Prusoff B, Weissman M, Goldin L. Multiple threshold models for the affective disorders: The Yale-NIMH collaborative family study. Journal Of Psychiatric Research 1985, 19: 533-546. PMID: 4078756, DOI: 10.1016/0022-3956(85)90071-8.Peer-Reviewed Original Research
1983
Can recovery from stuttering be considered a genetically milder subtype of stuttering?
Cox N, Kidd K. Can recovery from stuttering be considered a genetically milder subtype of stuttering? Behavior Genetics 1983, 13: 129-139. PMID: 6860250, DOI: 10.1007/bf01065662.Peer-Reviewed Original Research
1982
Genetic Strategies for the Analysis of Childhood Behavioral Traits
Pauls D, Kidd K. Genetic Strategies for the Analysis of Childhood Behavioral Traits. Schizophrenia Bulletin 1982, 8: 253-266. PMID: 6955941, DOI: 10.1093/schbul/8.2.253.Peer-Reviewed Original Research
1981
Dermo‐distortive urticaria: An autosomal dominant dermatologic disorder
Epstein P, Kidd K, Opitz J. Dermo‐distortive urticaria: An autosomal dominant dermatologic disorder. American Journal Of Medical Genetics 1981, 9: 307-315. PMID: 7294069, DOI: 10.1002/ajmg.1320090407.Peer-Reviewed Original Research
1980
Alternative genetic models for the analysis of complex traits.
Kidd K, Gladstien K. Alternative genetic models for the analysis of complex traits. Progress In Clinical And Biological Research 1980, 46: 407-35. PMID: 7022462.Peer-Reviewed Original ResearchImmunogenetic and population genetic analyses of Iberian cattle
Kidd K, Stone W, Crimella C, Carenzi C, Casati M, Rognoni G. Immunogenetic and population genetic analyses of Iberian cattle. Animal Genetics 1980, 11: 21-38. PMID: 7396241, DOI: 10.1111/j.1365-2052.1980.tb01489.x.Peer-Reviewed Original ResearchConceptsIberian breedsPopulation genetic analysesHalf-sib matingGene frequency dataEstimates of inbreedingAverage inbreeding coefficientSpanish cattle breedsGenetic distanceIberian cattleInbreeding coefficientGenetic analysisLidia breedCattle breedsEuropean breedsPortuguese breedsCodominant systemsPolymorphic systemsRelated groupsBreedsInbreedingCattleClose relationshipHeterozygosity