1996
Early presentation of metastatic medullary carcinoma in multiple endocrine neoplasia, type IIA: Implications for therapy
Gill J, Reyes-Múgica M, Iyengar S, Kidd K, Touloukian R, Smith C, Keller M, Genel M. Early presentation of metastatic medullary carcinoma in multiple endocrine neoplasia, type IIA: Implications for therapy. The Journal Of Pediatrics 1996, 129: 459-464. PMID: 8804341, DOI: 10.1016/s0022-3476(96)70084-7.Peer-Reviewed Original ResearchConceptsMedullary thyroid carcinomaMultiple endocrine neoplasiaEndocrine neoplasiaThyroid carcinomaMultifocal medullary thyroid carcinomaMetastatic medullary carcinomaElevated calcitonin levelsC-cell hyperplasiaType IIaAge 1 yearYears of ageYears 8 monthsYears 11 monthsIIA patientsLymph nodesCalcitonin levelsProphylactic thyroidectomyMedullary carcinomaStimulation testEarly presentationPositive findingsCarcinomaThyroidectomyNeoplasiaAge
1984
Onset of Major Depression in Early Adulthood: Increased Familial Loading and Specificity
Weissman M, Wickramaratne P, Merikangas K, Leckman J, Prusoff B, Caruso K, Kidd K, Gammon G. Onset of Major Depression in Early Adulthood: Increased Familial Loading and Specificity. JAMA Psychiatry 1984, 41: 1136-1143. PMID: 6508504, DOI: 10.1001/archpsyc.1984.01790230022003.Peer-Reviewed Original ResearchConceptsAge of onsetMajor depressionNormal control subjectsRelatives of probandsFamilial loadingControl subjectsEarly-onset depressionFirst-degree relativesYears of ageHigh familial loadingHigh riskNormal subjectsSpecificity of transmissionEarly adulthoodDepressionProbandsAgeMore studiesFamily studiesYoung personOnsetLater ageHomogeneous disorderSubjectsInverse relationship