2023
Making inroads to precision medicine for the treatment of autoimmune diseases: Harnessing genomic studies to better diagnose and treat complex disorders
Baglaenko Y, Wagner C, Bhoj V, Brodin P, Gershwin M, Graham D, Invernizzi P, Kidd K, Korsunsky I, Levy M, Mammen A, Nizet V, Ramirez-Valle F, Stites E, Williams M, Wilson M, Rose N, Ladd V, Sirota M. Making inroads to precision medicine for the treatment of autoimmune diseases: Harnessing genomic studies to better diagnose and treat complex disorders. Cambridge Prisms Precision Medicine 2023, 1: e25. PMID: 38550937, PMCID: PMC10953750, DOI: 10.1017/pcm.2023.14.Peer-Reviewed Original ResearchAutoimmune diseasesPrecision medicinePathogenic autoantigenPatient subtypesDisease heterogeneityComplex etiologyMolecular profilingDiseaseAccount individual variabilityDisease mechanismsForeign cellsMolecular pathwaysNatural defense systemComplex disorderDisease treatmentHealthy tissueIndividual variabilityOwn cellsTreatmentMedicineTherapeuticsDefense systemCurrent understandingCellsAutoantigens
1985
Drug response as a predictor of transmission of non-bipolar major depression within families
Prusoff B, Weissman M, Merikangas K, Leckman J, Kidd K. Drug response as a predictor of transmission of non-bipolar major depression within families. Journal Of Affective Disorders 1985, 8: 171-176. PMID: 3157727, DOI: 10.1016/0165-0327(85)90041-2.Peer-Reviewed Original ResearchConceptsNon-bipolar major depressionMajor depressionAffective illnessFirst-degree relativesTermination of treatmentRelatives of probandsClinical responsePharmacological therapyPoor responseClinical trialsSomatic treatmentsDistinct subtypesPredictors of transmissionFirst weekDrug responseFamilial aggregationRapid improvementDepressionProbandsHigh rateIllnessSubtypesTreatmentResponseTherapy
1982
The Epidemiology of Tourette's Syndrome: A Pilot Study
Jagger J, Prusoff B, Cohen D, Kidd K, Carbonari C, John K. The Epidemiology of Tourette's Syndrome: A Pilot Study. Schizophrenia Bulletin 1982, 8: 267-278. PMID: 6955942, DOI: 10.1093/schbul/8.2.267.Peer-Reviewed Original ResearchConceptsSyndrome patientsDiagnosis of TSTourette syndrome patientsTourette Syndrome AssociationUnpleasant side effectsMost patientsSelf-report questionnairesSyndrome AssociationEffective treatmentPatient membersSide effectsAlternative treatmentTourette syndromeDiscontinued usePatientsPilot studyHaloperidolSyndromeTreatmentQuestionnaireAttentional difficultiesSymptomsEpidemiologyDiagnosis