2022
North Asian population relationships in a global context
Kidd KK, Evsanaa B, Togtokh A, Brissenden JE, Roscoe JM, Dogan M, Neophytou PI, Gurkan C, Bulbul O, Cherni L, Speed WC, Murtha M, Kidd JR, Pakstis AJ. North Asian population relationships in a global context. Scientific Reports 2022, 12: 7214. PMID: 35508562, PMCID: PMC9068624, DOI: 10.1038/s41598-022-10706-x.Peer-Reviewed Original ResearchConceptsPopulation genetic studiesPhylogenetic tree analysisAutosomal variationSex chromosomesGenetic variationMost populationsGenetic studiesExtensive variationPopulation relationshipsGenome ConsortiumK projectNorth AsiaRefinement of analysisAsian ethnic groupsGlobal contextAutosomesTree analysisChromosomesAsia populationEthnic groupsMitochondriaPopulationMicrohaplotypesSmall subsetNative Americans
2021
STAT3 polymorphisms in North Africa and its implication in breast cancer
Ziadi W, Boussetta S, Elkamel S, Pakstis AJ, Kidd KK, Medimegh I, Elgaaied A, Cherni L. STAT3 polymorphisms in North Africa and its implication in breast cancer. Molecular Genetics & Genomic Medicine 2021, 9: e1744. PMID: 34251094, PMCID: PMC8404238, DOI: 10.1002/mgg3.1744.Peer-Reviewed Original ResearchConceptsNorth African populationsAfrican populationsSTAT3 regionSingle nucleotide polymorphismsRare haplotypesHsa-mirMiR databaseMajor haplotypesGenesNucleotide polymorphismsHaplotypesSNPsSTAT3Allele frequenciesRs7211777Tunisian populationPolymorphismPopulationDiversityNorth AfricaAllelesSignificant frequencyRecombinationAssaysCancer
2019
Population relationships based on 170 ancestry SNPs from the combined Kidd and Seldin panels
Pakstis AJ, Speed WC, Soundararajan U, Rajeevan H, Kidd JR, Li H, Kidd KK. Population relationships based on 170 ancestry SNPs from the combined Kidd and Seldin panels. Scientific Reports 2019, 9: 18874. PMID: 31827153, PMCID: PMC6906462, DOI: 10.1038/s41598-019-55175-x.Peer-Reviewed Original ResearchConceptsGenetic diversityPopulation relationshipsHuman populationAncestry informative SNP panelsInformative SNP panelsMajor continental regionsHuman reference populationsSNP panelIndividual populationsGenotype dataReference populationNative American populationsDiverse collectionAISNPsAllele frequency databasesWorldwide populationDiversityFrequency databaseAmerican populationReference population dataPopulationSNPsPrincipal component analysisCombined panelCluster patterns
2014
Maritime route of colonization of Europe
Paschou P, Drineas P, Yannaki E, Razou A, Kanaki K, Tsetsos F, Padmanabhuni SS, Michalodimitrakis M, Renda MC, Pavlovic S, Anagnostopoulos A, Stamatoyannopoulos JA, Kidd KK, Stamatoyannopoulos G. Maritime route of colonization of Europe. Proceedings Of The National Academy Of Sciences Of The United States Of America 2014, 111: 9211-9216. PMID: 24927591, PMCID: PMC4078858, DOI: 10.1073/pnas.1320811111.Peer-Reviewed Original ResearchConceptsSouthern European coastsGene flowGenome-wide DNA polymorphismsEuropean coastsWest clineDNA polymorphismsNeolithic farmersCoastal routeMediterranean SeaNetwork analysisMediterranean coastMainland EuropeNeolithic populationsCentral EuropeClineCoastGenesColonizationNear EastStriking structurePolymorphismPopulationAnatoliaHypothesisIslands
2011
Single nucleotide polymorphisms and haplotypes in Native American populations
Kidd JR, Friedlaender F, Pakstis AJ, Furtado M, Fang R, Wang X, Nievergelt CM, Kidd KK. Single nucleotide polymorphisms and haplotypes in Native American populations. American Journal Of Biological Anthropology 2011, 146: 495-502. PMID: 21913176, PMCID: PMC3658315, DOI: 10.1002/ajpa.21560.Peer-Reviewed Original ResearchConceptsSingle nucleotide polymorphismsNative American populationsAutosomal markersModern Native American populationsNucleotide polymorphismsOld World populationsEvolutionary relationshipsAmerican populationDifferent small setsDNA polymorphismsEurasian originAncestry inferenceMultiple populationsPolymorphismLarge comprehensive datasetAscertainment biasesNew WorldSmall independent setsMarkersComprehensive datasetClose relationshipPopulationHaplotypesNew information
2006
Sub‐Saharan African coding sequence variation and haplotype diversity at the NAT2 gene
Patin E, Harmant C, Kidd K, Kidd J, Froment A, Mehdi S, Sica L, Heyer E, Quintana‐Murci L. Sub‐Saharan African coding sequence variation and haplotype diversity at the NAT2 gene. Human Mutation 2006, 27: 720-720. PMID: 16786516, DOI: 10.1002/humu.9438.Peer-Reviewed Original ResearchConceptsNon-synonymous mutationsNovel non-synonymous mutationsEvolutionary conservationDetailed genetic characterizationIndividuals/populationsHaplotype diversityAgriculturalist populationsSequence variationProtein activityAfrican populationsWestern PygmiesAfrican haplotypesGenetic characterizationUnknown functional effectsGenesFunctional effectsNAT2 geneHaplotype frequenciesSub-Saharan African populationsMutationsChromosomesDamaging effectsLociPopulationProtein
1999
Global variation in the frequencies of functionally different catechol-O-methyltransferase alleles
Palmatier M, Kang A, Kidd K. Global variation in the frequencies of functionally different catechol-O-methyltransferase alleles. Biological Psychiatry 1999, 46: 557-567. PMID: 10459407, DOI: 10.1016/s0006-3223(99)00098-0.Peer-Reviewed Original ResearchConceptsRestriction site polymorphismsSingle nucleotide polymorphismsAllele frequenciesDifferent population frequenciesControl allele frequenciesEnzyme activity levelsAncestral alleleCandidate genesPopulation-based association studyAssociation studiesSite polymorphismFirst global surveyNucleotide polymorphismsAllelesEnzyme activityPopulation frequencyPolymorphismDifferent populationsCOMT enzyme activityActivity alleleLow-activity alleleGenesProteinGlobal variationPopulationLinkage Disequilibrium at the ADH2 and ADH3 Loci and Risk of Alcoholism
Osier M, Pakstis A, Kidd J, Lee J, Yin S, Ko H, Edenberg H, Lu R, Kidd K. Linkage Disequilibrium at the ADH2 and ADH3 Loci and Risk of Alcoholism. American Journal Of Human Genetics 1999, 64: 1147-1157. PMID: 10090900, PMCID: PMC1377839, DOI: 10.1086/302317.Peer-Reviewed Original ResearchMeSH KeywordsAlcohol DehydrogenaseAlcoholismAllelesBase SequenceChinaChromosomes, Human, Pair 4Cloning, MolecularGene FrequencyGenetic Predisposition to DiseaseGenetic VariationHaplotypesHumansIndians, Central AmericanLinkage DisequilibriumMexicoMolecular Sequence DataMultigene FamilyNative Hawaiian or Other Pacific IslanderPolymorphism, Single NucleotideRacial GroupsTaiwanConceptsProportion of chromosomesAlcohol dehydrogenase geneDehydrogenase geneChromosome 4Functional variantsChromosomesLinkage disequilibriumADH2Functional polymorphismsADH3Allele frequenciesPairwise disequilibriumGenesIntronic polymorphismDisequilibriumPolymorphismDifferent efficienciesRisk of alcoholismHigher VmaxClass I alcohol dehydrogenase (ADH) genesVariantsLociKbHaplotypesPopulationY‐chromosome specific YCAII, DYS19 and YAP polymorphisms in human populations: a comparative study
QUINTANA‐MURCI L, SEMINO O, POLONI E, LIU A, VAN GIJN M, PASSARINO G, BREGA A, NASIDZE I, MACCIONI L, COSSU G, AL‐ZAHERY N, KIDD J, KIDD K, SANTACHIARA‐BENERECETTI A. Y‐chromosome specific YCAII, DYS19 and YAP polymorphisms in human populations: a comparative study. Annals Of Human Genetics 1999, 63: 153-166. PMID: 10738527, DOI: 10.1046/j.1469-1809.1999.6320153.x.Peer-Reviewed Original ResearchConceptsY Alu PolymorphismGenetic structureGenetic affinityStrong genetic structurePopulation genetic structureAlu polymorphismsY markersHuman populationYCAIIDifferent populationsRelated groupsPolymorphismSpecific markersPopulationMarkersDYS19Geographic locationDifferent statistical analysesFrequency distributionSTRAffinityAllele Frequencies in a Worldwide Survey of a CA Repeat in the First Intron of the CFTR Gene
Mateu E, Calafell F, Bonné-Tamir B, Kidd J, Casals T, Kidd K, Bertranpetit J. Allele Frequencies in a Worldwide Survey of a CA Repeat in the First Intron of the CFTR Gene. Human Heredity 1999, 49: 15-20. PMID: 9858852, DOI: 10.1159/000022834.Peer-Reviewed Original ResearchConceptsCFTR geneIntron 1Allele frequenciesMolecular varianceGenetic varianceFirst intronDinucleotide CACA repeatsGenesCF mutationsHaplotypic analysisMutationsMajor geographical areasAfrican populationsUnknown mutationsAllele distributionPolymorphismCystic fibrosisIntronsChromosomesRepeatsGeographical regionsLociHeterozygosityPopulation
1998
Short tandem repeat polymorphism evolution in humans
Calafell F, Shuster A, Speed W, Kidd J, Kidd K. Short tandem repeat polymorphism evolution in humans. European Journal Of Human Genetics 1998, 6: 38-49. PMID: 9781013, DOI: 10.1038/sj.ejhg.5200151.Peer-Reviewed Original ResearchConceptsDinucleotide short tandem repeat polymorphismsStepwise mutation modelSet of populationsPrivate allelesShort tandem repeat polymorphismsGenetic distanceHigh heterozygosityGenetic variationLinkage analysisMutation modelPolymorphism evolutionTandem repeat polymorphismEuropean populationsModern humansHeterozygosityAllelesRepeat polymorphismAfrican sampleReplacement hypothesisEast AsiansDifferentiationHumansPolymorphismPopulationTrees
1996
Dynamics of the haplotype frequencies in populations: study using the Monte Carlo method.
Grigorenko E, Shikanian A, Kidd D, Dorig R, Kidd K. Dynamics of the haplotype frequencies in populations: study using the Monte Carlo method. Genetika 1996, 32: 1705-13. PMID: 9102365.Peer-Reviewed Original ResearchConceptsNatural selectionEffective population sizeRandom genetic driftMonte Carlo methodHaplotype frequenciesGenetic driftRandom matingEvolutionary dynamicsCarlo methodPopulation sizeRecurrent mutationsMutation processHarmonic meanFrequency dynamicsDifferent populationsSimulation resultsExperimental dataDynamicsMatingPopulationMutationsHaplotypesAllelesColonizationNew World colonization
1995
Apparent monomorphism of ALDH2 in seven American Indian populations
Novoradovsky A, Kidd J, Kidd K, Goldman D. Apparent monomorphism of ALDH2 in seven American Indian populations. Alcohol 1995, 12: 163-167. PMID: 7772269, DOI: 10.1016/0741-8329(94)00086-7.Peer-Reviewed Original ResearchConceptsNew World populationsSouth American Indian populationsALDH2 geneMitochondrial aldehyde dehydrogenaseNorth American populationsALDH2 cDNAALDH2 functionRestriction endonucleasesAldehyde dehydrogenaseConformation polymorphism techniqueSouth American IndiansGenesAllele-specific amplificationAllelesStudied individualsPolymorphism techniquePolymorphismAmerican populationFragmentsAmerican Indian populationsCDNAALDH2EndonucleaseVariantsPopulation
1991
Study of an additional 58 DNA markers in five human populations from four continents.
Bowcock A, Hebert J, Mountain J, Kidd J, Rogers J, Kidd K, Cavalli-Sforza L. Study of an additional 58 DNA markers in five human populations from four continents. Gene Geography 1991, 5: 151-73. PMID: 1841601.Peer-Reviewed Original ResearchDrift, admixture, and selection in human evolution: a study with DNA polymorphisms.
Bowcock A, Kidd J, Mountain J, Hebert J, Carotenuto L, Kidd K, Cavalli-Sforza L. Drift, admixture, and selection in human evolution: a study with DNA polymorphisms. Proceedings Of The National Academy Of Sciences Of The United States Of America 1991, 88: 839-843. PMID: 1992475, PMCID: PMC50909, DOI: 10.1073/pnas.88.3.839.Peer-Reviewed Original ResearchConceptsDNA polymorphismsEqual evolutionary ratesRandom genetic driftEvolutionary ratesGenetic driftEvolutionary analysisNatural selectionGenetic markersHuman evolutionGene frequenciesEarly admixtureHuman differentiationEvolutionary modelsPolymorphismHigh variationLow variationGenetic polymorphismsMeasures of variationGenesPopulationSpeciesObserved distributionDifferentiationVariationSelection
1986
Genetics of a wild population of rhesus monkeys (Macaca mulatta): II. The Dunga Gali population in species‐wide perspective
Melnick D, Jolly C, Kidd K. Genetics of a wild population of rhesus monkeys (Macaca mulatta): II. The Dunga Gali population in species‐wide perspective. American Journal Of Biological Anthropology 1986, 71: 129-140. PMID: 3799822, DOI: 10.1002/ajpa.1330710202.Peer-Reviewed Original ResearchConceptsGeneral genetic homogeneityTotal gene diversityClustering of populationsGene diversitySpecies rangeWild populationsZoogeographic dataGenetic diversityGeographic clinesGenetic variationGenetic variabilityGenetic homogeneityWestern groupLocal populationDiversityClineMajor regionsMacaca mulattaMigration modelGeneticsPopulationWild rhesus monkeysSimilar amountsVariationDifferent parts
1985
Genetic and evolutionary relationships among Asian Macaques
Melnick1 D, Kidd K. Genetic and evolutionary relationships among Asian Macaques. International Journal Of Primatology 1985, 6: 123-160. DOI: 10.1007/bf02693650.Peer-Reviewed Original ResearchEvolutionary relationshipsGenetic distanceSpecies groupsInferred evolutionary relationshipsEffective population sizeIntraspecific genetic distancesGene frequency dataMacaque speciesDivergence timesPhylogenetic treeAllele definitionGenetic differencesPopulation sizeCavalli-SforzaAsian macaquesSpeciesTree analysisLociPopulationTreesMajor sea-level changesFrequency dataSea-level changesAsia
1984
The genetics of a wild population of rhesus monkeys (Macaca mulatta). I. Genetic variability within and between social groups
Melnick D, Jolly C, Kidd K. The genetics of a wild population of rhesus monkeys (Macaca mulatta). I. Genetic variability within and between social groups. American Journal Of Biological Anthropology 1984, 63: 341-360. DOI: 10.1002/ajpa.1330630402.Peer-Reviewed Original ResearchGene flowIntergroup genetic differentiationSubstantial gene flowConsiderable genetic variationGenetic differentiationEcological isolationRapid speciationWild populationsGenetic variationGenetic evidenceGenetic variabilitySuch primatesStructural locusSocial subdivisionGene frequenciesSmall populationRhesus populationsRed cell hemolysatesDistribution of genotypesHimalayan foothillsLociGeneticsPopulationSpeciationDifferentiation
1981
A Comparison of Methods for Reconstructing Evolutionary Trees
Astolfi P, Kidd K, Cavalli-Sforza L. A Comparison of Methods for Reconstructing Evolutionary Trees. Systematic Biology 1981, 30: 156-169. DOI: 10.1093/sysbio/30.2.156.Peer-Reviewed Original Research
1978
Testing of Evolutionary Independence in Simulated Phylogenetic Trees
Astolfi P, Piazza A, Kidd K. Testing of Evolutionary Independence in Simulated Phylogenetic Trees. Systematic Biology 1978, 27: 391-400. DOI: 10.1093/sysbio/27.4.391.Peer-Reviewed Original ResearchIndependent evolutionEvolutionary independencePhylogenetic treeHybrid populationsIndependent populationsEvolutionary timeAncestor populationsGroups of populationsNumber of charactersSet of charactersCase of treesTreesHybridizationPopulation resultsEvolutionHybridization processPopulationTreenessLevel of complexityCharacterSuccessive splitsInitial populationFusion