Estimation of segregation and linkage parameters in simulated data. I. Segregation analyses with different ascertainment schemes.
Kramer P, Pauls D, Price R, Kidd K. Estimation of segregation and linkage parameters in simulated data. I. Segregation analyses with different ascertainment schemes. American Journal Of Human Genetics 1989, 45: 83-94. PMID: 2741953, PMCID: PMC1683375.Peer-Reviewed Original ResearchConceptsBetter parameter estimatesDifferent sampling schemesGenetic model parametersParameter estimatesSampling schemeModel parametersLinkage parametersHeterozygote penetranceSimulation studyDifferent ascertainment schemesAnalysis packagePedigree Analysis PackageSchemeInformation lossData setsParametersSample sizeModel