1987
Severity of Tourette's Syndrome in One Large Kindred: Implication for Determination of Disease Prevalence Rate
Kurlan R, Behr J, Medved L, Shoulson I, Pauls D, Kidd K. Severity of Tourette's Syndrome in One Large Kindred: Implication for Determination of Disease Prevalence Rate. JAMA Neurology 1987, 44: 268-269. PMID: 3469941, DOI: 10.1001/archneur.1987.00520150024013.Peer-Reviewed Original ResearchConceptsChronic motor ticsPrevalence ratesTourette syndromeSeverity of illnessAccurate prevalence ratesDisease prevalence ratesAutosomal dominant transmissionMotor ticsTic disordersVocal ticsMedical attentionStandardized questionnaireMedical careSyndromeLarge MennoniteApparent autosomal dominant transmissionDominant transmissionFamily membersSeverityMost casesIllnessCare
1986
Familial Tourette's syndrome: report of a large pedigree and potential for linkage analysis.
Kurlan R, Behr J, Medved L, Shoulson I, Pauls D, Kidd J, Kidd K. Familial Tourette's syndrome: report of a large pedigree and potential for linkage analysis. Neurology 1986, 36: 772-6. PMID: 3458031, DOI: 10.1212/wnl.36.6.772.Peer-Reviewed Original ResearchConceptsChronic motor ticsTourette syndromeDefinite Tourette's syndromePermanent lymphoblastoid cell linesDSM-III criteriaAutosomal dominant patternFamily membersClinical featuresMotor ticsVocal ticsLymphoblastoid cell linesStandardized questionnaireLarge MennoniteCell linesSyndromeDominant patternIndependent ratings