1988
Evidence against linkage of schizophrenia to markers on chromosome 5 in a northern Swedish pedigree
Kennedy J, Giuffra L, Moises H, Cavalli-Sforza L, Pakstis A, Kidd J, Castiglione C, Sjogren B, Wetterberg L, Kidd K. Evidence against linkage of schizophrenia to markers on chromosome 5 in a northern Swedish pedigree. Nature 1988, 336: 167-170. PMID: 2903450, DOI: 10.1038/336167a0.Peer-Reviewed Original ResearchConceptsImportant pathogenic roleGenetic factorsSevere mental illnessAetiologic factorsChronic coursePathogenic roleProximal long armGlucocorticoid receptorMental illnessSchizophreniaSchizophrenia casesLinkage of schizophreniaGenetic linkage studiesFamily studiesLong armDistal long armMarkersChromosome 5Linkage studiesSwedish pedigreeArmLinkage ProjectIllnessStrong evidenceFactors
1987
Severity of Tourette's Syndrome in One Large Kindred: Implication for Determination of Disease Prevalence Rate
Kurlan R, Behr J, Medved L, Shoulson I, Pauls D, Kidd K. Severity of Tourette's Syndrome in One Large Kindred: Implication for Determination of Disease Prevalence Rate. JAMA Neurology 1987, 44: 268-269. PMID: 3469941, DOI: 10.1001/archneur.1987.00520150024013.Peer-Reviewed Original ResearchConceptsChronic motor ticsPrevalence ratesTourette syndromeSeverity of illnessAccurate prevalence ratesDisease prevalence ratesAutosomal dominant transmissionMotor ticsTic disordersVocal ticsMedical attentionStandardized questionnaireMedical careSyndromeLarge MennoniteApparent autosomal dominant transmissionDominant transmissionFamily membersSeverityMost casesIllnessCareSearching for Major Genes for Psychiatric Disorders
Kidd K. Searching for Major Genes for Psychiatric Disorders. Novartis Foundation Symposia 1987, 130: 184-196. PMID: 2894929, DOI: 10.1002/9780470513507.ch11.Peer-Reviewed Original ResearchConceptsPsychiatric disordersManic-depressive illnessMajor psychiatric disordersGenetic linkage studiesDepressive illnessAetiological factorsLinkage studiesNeurochemical complexityCommon disorderBiochemical abnormalitiesFamilial clusteringMajor genetic componentGenetic factorsDisordersRestriction fragment length polymorphismReasonable evidenceFragment length polymorphismLength polymorphismGenetic componentEvidenceCandidate genesIllnessAbnormalitiesSuspicionBrain
1985
Drug response as a predictor of transmission of non-bipolar major depression within families
Prusoff B, Weissman M, Merikangas K, Leckman J, Kidd K. Drug response as a predictor of transmission of non-bipolar major depression within families. Journal Of Affective Disorders 1985, 8: 171-176. PMID: 3157727, DOI: 10.1016/0165-0327(85)90041-2.Peer-Reviewed Original ResearchConceptsNon-bipolar major depressionMajor depressionAffective illnessFirst-degree relativesTermination of treatmentRelatives of probandsClinical responsePharmacological therapyPoor responseClinical trialsSomatic treatmentsDistinct subtypesPredictors of transmissionFirst weekDrug responseFamilial aggregationRapid improvementDepressionProbandsHigh rateIllnessSubtypesTreatmentResponseTherapy
1984
Psychiatric Disorders in the Relatives of Probands With Affective Disorders: The Yale University—National Institute of Mental Health Collaborative Study
Weissman M, Gershon E, Kidd K, Prusoff B, Leckman J, Dibble E, Hamovit J, Thompson W, Pauls D, Guroff J. Psychiatric Disorders in the Relatives of Probands With Affective Disorders: The Yale University—National Institute of Mental Health Collaborative Study. JAMA Psychiatry 1984, 41: 13-21. PMID: 6691780, DOI: 10.1001/archpsyc.1984.01790120015003.Peer-Reviewed Original ResearchConceptsRelatives of probandsMajor depressionPsychiatric disordersAffective disordersMental Health Collaborative StudyComparable diagnostic criteriaFirst-degree relativesComparability of ratesDiagnostic criteriaBipolar disorderDepressed probandsMost disordersDisordersProbandsFamily studiesCollaborative studyRelativesAmbulatoryIllness
1982
The effects of requisite assumptions on linkage analyses of manic-depressive illness with HLA.
Kruger S, Turner W, Kidd K. The effects of requisite assumptions on linkage analyses of manic-depressive illness with HLA. Biological Psychiatry 1982, 17: 1081-99. PMID: 6959652.Peer-Reviewed Original Research