2021
Genetic diversity of the North African population revealed by the typing of SNPs in the DRD2/ANKK1 genomic region
Mestiri S, Boussetta S, Pakstis AJ, Elkamel S, Elgaaied ABA, Kidd KK, Cherni L. Genetic diversity of the North African population revealed by the typing of SNPs in the DRD2/ANKK1 genomic region. Gene 2021, 777: 145466. PMID: 33524518, DOI: 10.1016/j.gene.2021.145466.Peer-Reviewed Original ResearchMeSH KeywordsAdultAfrica, NorthernAllelesBlack PeopleEthnicityFemaleGene FrequencyGenetic Predisposition to DiseaseGenetic VariationGenomicsGenotypeGenotyping TechniquesHaplotypesHeterozygoteHuman MigrationHumansLinkage DisequilibriumMaleMiddle AgedPolymorphism, Single NucleotideProtein Serine-Threonine KinasesReceptors, Dopamine D2ConceptsNorth African populationsGenetic diversitySingle nucleotide polymorphismsGenetic structureAncestral gene poolPeculiar genetic structureLowest average heterozygosityNorth African onesAfrican populationsHigh linkage disequilibriumGenetic driftGenomic regionsAverage heterozygosityGene poolSame locusLinkage disequilibriumDisequilibrium analysisGenetic componentGenesNucleotide polymorphismsLociReceptor geneDiversityHuman populationEuropean populations
2019
Population relationships based on 170 ancestry SNPs from the combined Kidd and Seldin panels
Pakstis AJ, Speed WC, Soundararajan U, Rajeevan H, Kidd JR, Li H, Kidd KK. Population relationships based on 170 ancestry SNPs from the combined Kidd and Seldin panels. Scientific Reports 2019, 9: 18874. PMID: 31827153, PMCID: PMC6906462, DOI: 10.1038/s41598-019-55175-x.Peer-Reviewed Original ResearchConceptsGenetic diversityPopulation relationshipsHuman populationAncestry informative SNP panelsInformative SNP panelsMajor continental regionsHuman reference populationsSNP panelIndividual populationsGenotype dataReference populationNative American populationsDiverse collectionAISNPsAllele frequency databasesWorldwide populationDiversityFrequency databaseAmerican populationReference population dataPopulationSNPsPrincipal component analysisCombined panelCluster patterns
2011
Analyses of a set of 128 ancestry informative single-nucleotide polymorphisms in a global set of 119 population samples
Kidd JR, Friedlaender FR, Speed WC, Pakstis AJ, De La Vega FM, Kidd KK. Analyses of a set of 128 ancestry informative single-nucleotide polymorphisms in a global set of 119 population samples. Investigative Genetics 2011, 2: 1. PMID: 21208434, PMCID: PMC3025953, DOI: 10.1186/2041-2223-2-1.Peer-Reviewed Original ResearchAncestry informative single nucleotide polymorphismsInformative single nucleotide polymorphismsSingle nucleotide polymorphismsTrait association studiesAncestry informative markersForensic ancestry inferencePopulation structureEurasian populationsAdmixture mappingAssociation studiesAncestry inferenceAncestry assignmentInformative markersAdmixture studiesIndividual ancestryHuman populationNumber of individualsAncestryAllele frequenciesMarker panelOriginal selectionPopulation sampleSpecific setStructure programPolymorphism
2008
Global patterns of variation in allele and haplotype frequencies and linkage disequilibrium across the CYP2E1 gene
Lee M, Mukherjee N, Pakstis A, Khaliq S, Mohyuddin A, Mehdi S, Speed W, Kidd J, Kidd K. Global patterns of variation in allele and haplotype frequencies and linkage disequilibrium across the CYP2E1 gene. The Pharmacogenomics Journal 2008, 8: 349-356. PMID: 18663376, PMCID: PMC2782390, DOI: 10.1038/tpj.2008.9.Peer-Reviewed Original ResearchConceptsGenetic variationGene expressionAssociation studiesFamily of enzymesDifferent human populationsHaplotype variationHuman population samplesMajor geographical regionsTandem repeatsPolymorphism haplotypesGenesMultiple populationsHaplotypesSusceptibility mutationsGlobal patternsHuman populationAdditional polymorphismsHaplotype frequenciesCentral roleDifferent populationsDiverse patternsEndogenous compoundsDisequilibriumLD dataPolymorphism
1999
Y‐chromosome specific YCAII, DYS19 and YAP polymorphisms in human populations: a comparative study
QUINTANA‐MURCI L, SEMINO O, POLONI E, LIU A, VAN GIJN M, PASSARINO G, BREGA A, NASIDZE I, MACCIONI L, COSSU G, AL‐ZAHERY N, KIDD J, KIDD K, SANTACHIARA‐BENERECETTI A. Y‐chromosome specific YCAII, DYS19 and YAP polymorphisms in human populations: a comparative study. Annals Of Human Genetics 1999, 63: 153-166. PMID: 10738527, DOI: 10.1046/j.1469-1809.1999.6320153.x.Peer-Reviewed Original ResearchConceptsY Alu PolymorphismGenetic structureGenetic affinityStrong genetic structurePopulation genetic structureAlu polymorphismsY markersHuman populationYCAIIDifferent populationsRelated groupsPolymorphismSpecific markersPopulationMarkersDYS19Geographic locationDifferent statistical analysesFrequency distributionSTRAffinity
1998
Network Analyses of Y-Chromosomal Types in Europe, Northern Africa, and Western Asia Reveal Specific Patterns of Geographic Distribution
Malaspina P, Cruciani F, Ciminelli B, Terrenato L, Santolamazza P, Alonso A, Banyko J, Brdicka R, García O, Gaudiano C, Guanti G, Kidd K, Lavinha J, Avila M, Mandich P, Moral P, Qamar R, Mehdi S, Ragusa A, Stefanescu G, Caraghin M, Tyler-Smith C, Scozzari R, Novelletto A. Network Analyses of Y-Chromosomal Types in Europe, Northern Africa, and Western Asia Reveal Specific Patterns of Geographic Distribution. American Journal Of Human Genetics 1998, 63: 847-860. PMID: 9718330, PMCID: PMC1377388, DOI: 10.1086/301999.Peer-Reviewed Original ResearchConceptsExtant human populationsTotal diversityChromosomal lineagesLength variantsDinucleotide microsatellitesY chromosomeCommon descentPhenetic relationshipsGeographic distributionNorthern AfricaHaplotypesHuman populationLineagesDinucleotide unitsRapid generationDiversityWestern AsiaNetwork analysisChromosomesMicrosatellitesSpecific patternsOptimal markerReliable frequency estimatesMutationsExtinctionA Global Haplotype Analysis of the Myotonic Dystrophy Locus: Implications for the Evolution of Modern Humans and for the Origin of Myotonic Dystrophy Mutations
Tishkoff S, Goldman A, Calafell F, Speed W, Deinard A, Bonne-Tamir B, Kidd J, Pakstis A, Jenkins T, Kidd K. A Global Haplotype Analysis of the Myotonic Dystrophy Locus: Implications for the Evolution of Modern Humans and for the Origin of Myotonic Dystrophy Mutations. American Journal Of Human Genetics 1998, 62: 1389-1402. PMID: 9585589, PMCID: PMC1377140, DOI: 10.1086/301861.Peer-Reviewed Original ResearchConceptsNon-African populationsHaplotype diversityMyotonic dystrophy locusRecent African origin modelLinkage disequilibriumMyotonic dystrophy mutationModern human evolutionModern humansGlobal haplotype analysisMutation eventsStrong linkage disequilibriumNonhuman primate speciesPrimate speciesHuman evolutionHuman populationShared pattern
1997
Survey of Maximum CTG/CAG Repeat Lengths in Humans and Non-Human Primates: Total Genome Scan in Populations Using the Repeat Expansion Detection Method
Sirugo G, Deinard A, Kidd J, Kidd K. Survey of Maximum CTG/CAG Repeat Lengths in Humans and Non-Human Primates: Total Genome Scan in Populations Using the Repeat Expansion Detection Method. Human Molecular Genetics 1997, 6: 403-408. PMID: 9147643, DOI: 10.1093/hmg/6.3.403.Peer-Reviewed Original ResearchConceptsCTG/CAGPygmy chimpanzeesCommon chimpanzeesRepeat lengthRandom genetic driftOrang-utansHuman populationDisease association studiesGenetic driftHuman genomeOverall mutation rateGenome scanAssociation studiesMutation rateBiaka PygmiesExpansion mutationRepeat expansionTotal genome scanPopulation differencesPopulation stratificationNon-human primatesRepeat expansion detection (RED) methodExpansion detectionChimpanzeesMutations
1996
A nuclear perspective on human evolution
Kidd K, Kidd J. A nuclear perspective on human evolution. 1996, 242-264. DOI: 10.1017/cbo9780511525643.018.Peer-Reviewed Original ResearchHuman diversity studiesHuman populationDNA sequence variationHuman evolutionAbsence of recombinationRecent human evolutionHuman genome diversityY-chromosome DNAPatterns of variationEvolutionary forcesExtant diversityVariety of speciesGenome diversityGenetic diversitySex chromosomesAutosomal DNAMitochondrial DNATaxonomic issuesGenomic diversityChromosome DNADiversity studiesEvolutionary factorsRecent ancestorSequence variationNuclear perspectiveDistribution and frequency of a polymorphicAlu insertion at the plasminogen activator locus in humans
Tishkoff S, Ruano G, Kidd J, Kidd K. Distribution and frequency of a polymorphicAlu insertion at the plasminogen activator locus in humans. Human Genetics 1996, 97: 759-764. PMID: 8641693, DOI: 10.1007/bf02346186.Peer-Reviewed Original ResearchConceptsPlasminogen activator geneHuman populationTissue plasminogen activator geneRestriction fragment length polymorphismActivator geneActivator locusInsertion eventsFragment length polymorphismPLAT locusHuman evolutionPolymerase chain reaction analysisChain reaction analysisLength polymorphismPresence/absenceAllele frequenciesAllelesLociModern humansNucleotide polymorphism, effective population size, and dispersal distances in the yellow baboons (Papio hamadryas cynocephalus) of Mikumi National Park, Tanzania
Rogers J, Kidd K. Nucleotide polymorphism, effective population size, and dispersal distances in the yellow baboons (Papio hamadryas cynocephalus) of Mikumi National Park, Tanzania. American Journal Of Primatology 1996, 38: 157-168. PMID: 31918472, DOI: 10.1002/(sici)1098-2345(1996)38:2<157::aid-ajp4>3.0.co;2-y.Peer-Reviewed Original ResearchGenetic variabilityDNA polymorphismsInbreeding effective population sizeEffective population sizeDNA sequence dataMale dispersal distancesNuclear DNA polymorphismsNucleotide heterozygosityNatural populationsRestriction fragment length polymorphismMikumi National ParkDispersal distanceWright's isolationPopulation structureSequence dataAutosomal lociGenetic methodsFragment length polymorphismPopulation dynamicsPopulation sizeNational ParkSouthern blottingLength polymorphismHuman populationYellow baboons
1994
Detection of DNA sequence variation via deliberate heteroduplex formation from genomic DNAs amplified en masse in "population tubes".
Ruano G, Deinard A, Tishkoff S, Kidd K. Detection of DNA sequence variation via deliberate heteroduplex formation from genomic DNAs amplified en masse in "population tubes". Genome Research 1994, 3: 225-231. PMID: 8173512, DOI: 10.1101/gr.3.4.225.Peer-Reviewed Original ResearchConceptsDNA sequence variationSequence variationGenomic DNAGlucose-6-phosphate dehydrogenase geneX chromosome lociWide geographic distributionLarge-scale samplingLong intronsDehydrogenase geneAllelic variationHeteroduplex moleculesGeographic distributionAllelic variantsHeteroduplex formationChimpanzee samplesHuman populationGradient electrophoresisRare variantsDNAGradient gelsHeteroduplexesElectrophoresisIntronsGenesLoci
1991
Study of an additional 58 DNA markers in five human populations from four continents.
Bowcock A, Hebert J, Mountain J, Kidd J, Rogers J, Kidd K, Cavalli-Sforza L. Study of an additional 58 DNA markers in five human populations from four continents. Gene Geography 1991, 5: 151-73. PMID: 1841601.Peer-Reviewed Original Research