1996
Distribution and frequency of a polymorphicAlu insertion at the plasminogen activator locus in humans
Tishkoff S, Ruano G, Kidd J, Kidd K. Distribution and frequency of a polymorphicAlu insertion at the plasminogen activator locus in humans. Human Genetics 1996, 97: 759-764. PMID: 8641693, DOI: 10.1007/bf02346186.Peer-Reviewed Original ResearchConceptsPlasminogen activator geneHuman populationTissue plasminogen activator geneRestriction fragment length polymorphismActivator geneActivator locusInsertion eventsFragment length polymorphismPLAT locusHuman evolutionPolymerase chain reaction analysisChain reaction analysisLength polymorphismPresence/absenceAllele frequenciesAllelesLociModern humansDRD2 Haplotypes Containing the TaqI A1 Allele: Implications for Alcoholism Research
Kidd K, Pakstis A, Castiglione C, Kidd J, Speed W, Goldman D, Knowler W, Lu R, Bonne‐Tamir B. DRD2 Haplotypes Containing the TaqI A1 Allele: Implications for Alcoholism Research. Alcohol Clinical And Experimental Research 1996, 20: 697-705. PMID: 8800387, DOI: 10.1111/j.1530-0277.1996.tb01674.x.Peer-Reviewed Original ResearchMeSH KeywordsAlcoholismAllelesAnimalsChromosome MappingDeoxyribonucleases, Type II Site-SpecificEthnicityGene FrequencyGenetics, PopulationHaplotypesHumansPolymerase Chain ReactionPolymorphism, GeneticPolymorphism, Restriction Fragment LengthReceptors, Dopamine D2Repetitive Sequences, Nucleic AcidResearchConceptsGenetic variationAssociation studiesUnrelated control samplesDopamine D2 receptor locusDiversity of haplotypesShort tandem repeat polymorphismsDRD2 locusEvolutionary historyRestriction fragment length polymorphismPopulation geneticsPhylogenetic originFragment length polymorphismAncestral originReceptor locusHomologous regionsIntron 2LociAllelic systemHigher primatesHaplotypesTandem repeat polymorphismAllelesConsiderable diversityDRD2 haplotypesPolymorphismNucleotide polymorphism, effective population size, and dispersal distances in the yellow baboons (Papio hamadryas cynocephalus) of Mikumi National Park, Tanzania
Rogers J, Kidd K. Nucleotide polymorphism, effective population size, and dispersal distances in the yellow baboons (Papio hamadryas cynocephalus) of Mikumi National Park, Tanzania. American Journal Of Primatology 1996, 38: 157-168. PMID: 31918472, DOI: 10.1002/(sici)1098-2345(1996)38:2<157::aid-ajp4>3.0.co;2-y.Peer-Reviewed Original ResearchGenetic variabilityDNA polymorphismsInbreeding effective population sizeEffective population sizeDNA sequence dataMale dispersal distancesNuclear DNA polymorphismsNucleotide heterozygosityNatural populationsRestriction fragment length polymorphismMikumi National ParkDispersal distanceWright's isolationPopulation structureSequence dataAutosomal lociGenetic methodsFragment length polymorphismPopulation dynamicsPopulation sizeNational ParkSouthern blottingLength polymorphismHuman populationYellow baboons
1992
Variability in nuclear DNA among nonhuman primates: Application of molecular genetic techniques to intra‐ and inter‐species genetic analyses
Rogers J, Ruano G, Kidd K. Variability in nuclear DNA among nonhuman primates: Application of molecular genetic techniques to intra‐ and inter‐species genetic analyses. American Journal Of Primatology 1992, 27: 93-105. PMID: 31948144, DOI: 10.1002/ajp.1350270205.Peer-Reviewed Original ResearchDNA clonesSequence informationMolecular geneticsCross-species PCRIntra-species polymorphismBeta-globin gene clusterNuclear DNA clonesHuman genetic analysisHuman molecular geneticsNucleotide sequence informationNuclear lociGradient gel electrophoresisDNA variationRestriction fragment length polymorphismGene clusterMolecular variabilityGenetic analysisFragment length polymorphismLociLength polymorphismPolymerase chain reaction amplificationGel electrophoresisSpecies differencesGeneticsChain reaction amplification
1991
Studies of three Amerindian populations using nuclear DNA polymorphisms.
Kidd J, Black F, Weiss K, Balazs I, Kidd K. Studies of three Amerindian populations using nuclear DNA polymorphisms. Human Biology 1991, 63: 775-94. PMID: 1683642.Peer-Reviewed Original Research
1990
Linkage relationships of human arginine vasopressin-neurophysin-II and oxytocin-neurophysin-I to prodynorphin and other loci on chromosome 20.
Summar M, Phillips J, Battey J, Castiglione C, Kidd K, Maness K, Weiffenbach B, Gravius T. Linkage relationships of human arginine vasopressin-neurophysin-II and oxytocin-neurophysin-I to prodynorphin and other loci on chromosome 20. Endocrinology 1990, 4: 947-50. PMID: 1978246, DOI: 10.1210/mend-4-6-947.Peer-Reviewed Original ResearchConceptsLinkage relationshipsChromosome 20Restriction fragment length polymorphismCentre d'Etude du Polymorphisme Humain (CEPH) collectionFragment length polymorphismShort armAnonymous DNA segmentsSomatic cell hybridsLength polymorphismDistal short armSame neurosecretory granulesStructural geneTranscriptional associationsHuman genomeCell hybridsDNA segmentsLocus mapsMultilocus linkage analysisClose physical relationshipLinkage analysisSouthern blotOdds (LOD) scoreLociGenesClose linkageThe locus for the medium-chain acyl-CoA dehydrogenase gene on chromosome 1 is highly polymorphic
Kidd J, Matsubara Y, Castiglione C, Tanaka K, Kidd K. The locus for the medium-chain acyl-CoA dehydrogenase gene on chromosome 1 is highly polymorphic. Genomics 1990, 6: 89-93. PMID: 1968047, DOI: 10.1016/0888-7543(90)90451-y.Peer-Reviewed Original ResearchConceptsRestriction fragment length polymorphismMedium-chain acyl-CoA dehydrogenase (MCAD) geneAcyl-CoA dehydrogenase geneSomatic cell studiesMedium-chain acyl-CoA dehydrogenaseSignificant linkage disequilibriumAcyl-CoA dehydrogenaseLinkage mappingDehydrogenase geneRegional assignmentChromosome 1Fragment length polymorphismGenetic studiesLinkage analysisLinkage disequilibriumSitu hybridizationLength polymorphismLinkage studiesPGM1Clinical genetic studiesACADMGenesLociCell localizationRFLP systems
1989
The β subunit locus of the human fibronectin receptor: DNA restriction fragment length polymorphism and linkage mapping studies
Wu J, Giuffra L, Goodfellow P, Myers S, Carson N, Anderson L, Hoyle L, Simpson N, Kidd K. The β subunit locus of the human fibronectin receptor: DNA restriction fragment length polymorphism and linkage mapping studies. Human Genetics 1989, 83: 383-390. PMID: 2572537, DOI: 10.1007/bf00291386.Peer-Reviewed Original ResearchMeSH KeywordsChromosome MappingChromosomes, Human, Pair 1Chromosomes, Human, Pair 10Chromosomes, Human, Pair 17Chromosomes, Human, Pair 21DNADNA ProbesDNA, NeoplasmFemaleGenetic LinkageGenetic MarkersHaplotypesHumansMaleMultiple Endocrine NeoplasiaPolymorphism, Restriction Fragment LengthReceptors, FibronectinReceptors, ImmunologicConceptsRestriction fragment length polymorphismHuman fibronectin receptorCDNA clonesFragment length polymorphismLinkage analysisDNA restriction fragment length polymorphismsMultiple restriction fragment length polymorphismsPolymorphism information content (PIC) valuesFibronectin receptorHighest polymorphism information content valuePartial cDNA cloneInformation content valuesLength polymorphismLinkage studiesPairwise linkage analysisSouthern blot analysisTypes of polymorphismsChromosome 10 markersGenomic clonesPericentromeric regionTransmembrane proteinDNA markersGenetic linkage studiesDNA sequencesSingle locusOne Form of Bipolar Affective Disorder is Mapped to Chromosome 11
Kidd K, Egeland J, Gerhard D, Pauls D, Sussex J, Allen C, Hostetter A, Kidd J, Pakstis A, Housman D. One Form of Bipolar Affective Disorder is Mapped to Chromosome 11. 1989, 184-187. DOI: 10.1007/978-1-4612-3524-8_41.Peer-Reviewed Original ResearchComplex human disordersGenetic linkageGenetic markersHuman disordersComplex traitsRestriction fragment length polymorphismHuman genomeFragment length polymorphismMajor locusChromosome 11Length polymorphismBipolar affective disorderGenomeLociTraitsDNAMarkersLinkageGeneticistsPolymorphismLarge numberDiscoveryFirst step
1988
The Anonymous RFLP Locus D1S2 Is Close to PGMl on Chromosome 1
Kidd K, Kidd J, Castiglione C, Sparkes R, Egeland J, Bakker E. The Anonymous RFLP Locus D1S2 Is Close to PGMl on Chromosome 1. Human Heredity 1988, 38: 22-26. PMID: 2895061, DOI: 10.1159/000153749.Peer-Reviewed Original ResearchConceptsRestriction fragment length polymorphismSomatic cell hybridsSouthern blot analysisGenetic mapCell hybridsChromosome 1Fragment length polymorphismShort armD1S2
1987
Assignment of multiple endocrine neoplasia type 2A to chromosome 10 by linkage
Simpson N, Kidd K, Goodfellow P, McDermid H, Myers S, Kidd J, Jackson C, Duncan A, Farrer L, Brasch K, Castiglione C, Genel M, Gertner J, Greenberg C, Gusella J, Holden J, White B. Assignment of multiple endocrine neoplasia type 2A to chromosome 10 by linkage. Nature 1987, 328: 528-530. PMID: 2886918, DOI: 10.1038/328528a0.Peer-Reviewed Original ResearchConceptsRestriction fragment length polymorphismIRBP geneNew DNA markersDifferent restriction fragment length polymorphismsPairwise linkage analysisChromosome 10 markersDNA markersFragment length polymorphismMaximum lod scoreLinkage analysisDisease locusLociMEN2A locusLOD scoreLength polymorphismGenesMultipoint analysisSecondary sitesType 2ADominant fashionKinds of cancersBipolar affective disorders linked to DNA markers on chromosome 11
Egeland J, Gerhard D, Pauls D, Sussex J, Kidd K, Alien C, Hostetter A, Housman D. Bipolar affective disorders linked to DNA markers on chromosome 11. Nature 1987, 325: 783-787. PMID: 2881209, DOI: 10.1038/325783a0.Peer-Reviewed Original ResearchConceptsChromosome 11Old Order Amish pedigreeRestriction fragment length polymorphismDNA markersDominant geneAmish pedigreeFragment length polymorphismShort armLength polymorphismSearching for Major Genes for Psychiatric Disorders
Kidd K. Searching for Major Genes for Psychiatric Disorders. Novartis Foundation Symposia 1987, 130: 184-196. PMID: 2894929, DOI: 10.1002/9780470513507.ch11.Peer-Reviewed Original ResearchConceptsPsychiatric disordersManic-depressive illnessMajor psychiatric disordersGenetic linkage studiesDepressive illnessAetiological factorsLinkage studiesNeurochemical complexityCommon disorderBiochemical abnormalitiesFamilial clusteringMajor genetic componentGenetic factorsDisordersRestriction fragment length polymorphismReasonable evidenceFragment length polymorphismLength polymorphismGenetic componentEvidenceCandidate genesIllnessAbnormalitiesSuspicionBrain
1986
Linkage Analyses of Multiple Endocrine Neoplasia, Type 2A (MEN-2A) with 20 DNA Polymorphisms: 5% of the Genome Excluded
Kidd K, Kidd J, Castiglione C, Genel M, Darby J, Cavalli-Sforza L, Gusella J. Linkage Analyses of Multiple Endocrine Neoplasia, Type 2A (MEN-2A) with 20 DNA Polymorphisms: 5% of the Genome Excluded. Human Heredity 1986, 36: 243-249. PMID: 2875939, DOI: 10.1159/000153634.Peer-Reviewed Original ResearchLinkage Analysis in a Family with Dominantly Inherited Torsion Dystonia: Exclusion of the Pro-Opiomelanocortin and Glutamic Acid Decarboxylase Genes and Other Chromosomal Regions Using DNA Polymorphisms
Breakefield X, Bressman S, Kramer P, Ozelius L, Moskowitz C, Tanzi R, Brin M, Hobbs W, Kaufman D, Tobin A, Kidd K, Fahn S, Gusella J. Linkage Analysis in a Family with Dominantly Inherited Torsion Dystonia: Exclusion of the Pro-Opiomelanocortin and Glutamic Acid Decarboxylase Genes and Other Chromosomal Regions Using DNA Polymorphisms. Journal Of Neurogenetics 1986, 3: 159-175. PMID: 3016220, DOI: 10.3109/01677068609106846.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedChildChild, PreschoolChromosome DeletionChromosome MappingCloning, MolecularDNADNA Restriction EnzymesDystonia Musculorum DeformansFemaleGenesGenes, DominantGenetic LinkageGlutamate DecarboxylaseHumansLymphocytesMaleMiddle AgedPedigreePolymorphism, GeneticPro-OpiomelanocortinConceptsLinkage analysisGlutamic acid decarboxylase geneRestriction fragment length polymorphismDecarboxylase geneDNA sequencesMode of inheritanceChromosomal regionsDNA polymorphismsFragment length polymorphismDefective geneLod score methodGenesDNA probesLength polymorphismLymphoblast linesInheritanceDisease statesAutosomal dominant modeGene penetranceSequenceFamilyPolymorphismGenomeAcid decarboxylaseRequisite assumptions