Assignment of multiple endocrine neoplasia type 2A to chromosome 10 by linkage
Simpson N, Kidd K, Goodfellow P, McDermid H, Myers S, Kidd J, Jackson C, Duncan A, Farrer L, Brasch K, Castiglione C, Genel M, Gertner J, Greenberg C, Gusella J, Holden J, White B. Assignment of multiple endocrine neoplasia type 2A to chromosome 10 by linkage. Nature 1987, 328: 528-530. PMID: 2886918, DOI: 10.1038/328528a0.Peer-Reviewed Original ResearchConceptsRestriction fragment length polymorphismIRBP geneNew DNA markersDifferent restriction fragment length polymorphismsPairwise linkage analysisChromosome 10 markersDNA markersFragment length polymorphismMaximum lod scoreLinkage analysisDisease locusLociMEN2A locusLOD scoreLength polymorphismGenesMultipoint analysisSecondary sitesType 2ADominant fashionKinds of cancers