1988
Migraine and depression: Association and familial transmission
Merikangas K, Risch N, Merikangas J, Weissman M, Kidd K. Migraine and depression: Association and familial transmission. Journal Of Psychiatric Research 1988, 22: 119-129. PMID: 3404480, DOI: 10.1016/0022-3956(88)90076-3.Peer-Reviewed Original Research
1987
Early Onset (Under Age 30 Years) and Panic Disorder as Markers for Etiologic Homogeneity in Major Depression
Price R, Kidd K, Weissman M. Early Onset (Under Age 30 Years) and Panic Disorder as Markers for Etiologic Homogeneity in Major Depression. JAMA Psychiatry 1987, 44: 434-440. PMID: 3472494, DOI: 10.1001/archpsyc.1987.01800170048008.Peer-Reviewed Original ResearchConceptsEarly onsetMajor depressionPanic disorderLate-onset depressionPrevalence of depressionElevation of riskFamilies of probandsYale Family StudyEtiologic homogeneityHigh riskPatterns of transmissionOlder age cohortsRestriction of analysisDepressionPopulation ratesFamily studiesProbandsOnsetDisordersAge cohortsRiskGenetic modelsSample sizeCohortPrevalence
1986
Understanding the Clinical Heterogeneity of Major Depression Using Family Data
Weissman M, Merikangas K, Priya W, Kidd K, Prusoff B, Leckman J, Pauls D. Understanding the Clinical Heterogeneity of Major Depression Using Family Data. JAMA Psychiatry 1986, 43: 430-434. PMID: 3964021, DOI: 10.1001/archpsyc.1986.01800050028003.Peer-Reviewed Original ResearchConceptsMajor depressionSymptom patternsHistory of hospitalizationClinical presentationClinical severityRecurrent depressionSecondary alcoholismClinical heterogeneitySuicidal ideationAnxiety disordersDepressionFamilial aggregationEarly ageDisordersCombination of criteriaAgeSubgroupsRiskOnsetPutative subgroupsHospitalization
1985
Drug response as a predictor of transmission of non-bipolar major depression within families
Prusoff B, Weissman M, Merikangas K, Leckman J, Kidd K. Drug response as a predictor of transmission of non-bipolar major depression within families. Journal Of Affective Disorders 1985, 8: 171-176. PMID: 3157727, DOI: 10.1016/0165-0327(85)90041-2.Peer-Reviewed Original ResearchConceptsNon-bipolar major depressionMajor depressionAffective illnessFirst-degree relativesTermination of treatmentRelatives of probandsClinical responsePharmacological therapyPoor responseClinical trialsSomatic treatmentsDistinct subtypesPredictors of transmissionFirst weekDrug responseFamilial aggregationRapid improvementDepressionProbandsHigh rateIllnessSubtypesTreatmentResponseTherapy
1984
Onset of Major Depression in Early Adulthood: Increased Familial Loading and Specificity
Weissman M, Wickramaratne P, Merikangas K, Leckman J, Prusoff B, Caruso K, Kidd K, Gammon G. Onset of Major Depression in Early Adulthood: Increased Familial Loading and Specificity. JAMA Psychiatry 1984, 41: 1136-1143. PMID: 6508504, DOI: 10.1001/archpsyc.1984.01790230022003.Peer-Reviewed Original ResearchConceptsAge of onsetMajor depressionNormal control subjectsRelatives of probandsFamilial loadingControl subjectsEarly-onset depressionFirst-degree relativesYears of ageHigh familial loadingHigh riskNormal subjectsSpecificity of transmissionEarly adulthoodDepressionProbandsAgeMore studiesFamily studiesYoung personOnsetLater ageHomogeneous disorderSubjectsInverse relationshipSubtypes of Depression: Family Study Perspective
Leckman J, Weissman M, Prusoff B, Caruso K, Merikangas K, Pauls D, Kidd K. Subtypes of Depression: Family Study Perspective. JAMA Psychiatry 1984, 41: 833-838. PMID: 6466042, DOI: 10.1001/archpsyc.1984.01790200015002.Peer-Reviewed Original ResearchPsychopathology in the Children (Ages 6–18) of Depressed and Normal Parents
WEISSMAN M, PRUSOFF B, GAMMON G, MERIKANGAS K, LECKMAN J, KIDD K. Psychopathology in the Children (Ages 6–18) of Depressed and Normal Parents. Journal Of The American Academy Of Child & Adolescent Psychiatry 1984, 23: 78-84. PMID: 6693680, DOI: 10.1097/00004583-198401000-00011.Peer-Reviewed Original ResearchConceptsDSM-III diagnosesFirst-degree relativesMajor depressionPsychiatric disordersProbands' first-degree relativesChildren of probandsCommon psychiatric disordersDirect interview studyFamily history studyClinical statusPsychiatric illnessNormal controlsDepressed probandsPsychological symptomsSuicidal behaviorEarly onsetDiagnosisDepressionSignificant predictorsProbandsAttention deficitsChildrenRiskEmotional problemsNormal parents
1982
Comparison of the family history method to direct interview Factors affecting the diagnosis of depression
Orvaschel H, Thompson W, Belanger A, Prusoff B, Kidd K. Comparison of the family history method to direct interview Factors affecting the diagnosis of depression. Journal Of Affective Disorders 1982, 4: 49-59. PMID: 6461687, DOI: 10.1016/0165-0327(82)90019-2.Peer-Reviewed Original ResearchConceptsDiagnosis of depressionFamily history reportsEndogenous symptomsHistory reportsFirst-degree relativesSADS-L interviewsFamily history criteriaSymptoms of depressionAge of onsetFamily history methodIllness characteristicsPsychiatric statusSpecific symptomsSevere casesTreatment statusSymptomsHistory criteriaDepressionSubject characteristicsDiagnosis
1980
Children and depression The children of depressed parents; The childhood of depressed patients; Depression in children
Orvaschel H, Weissman M, Kidd K. Children and depression The children of depressed parents; The childhood of depressed patients; Depression in children. Journal Of Affective Disorders 1980, 2: 1-16. PMID: 6448876, DOI: 10.1016/0165-0327(80)90017-8.Peer-Reviewed Original Research