2019
Antihypertensive medications and risk for incident dementia and Alzheimer's disease: a meta-analysis of individual participant data from prospective cohort studies
Ding J, Davis-Plourde KL, Sedaghat S, Tully PJ, Wang W, Phillips C, Pase MP, Himali JJ, Windham B, Griswold M, Gottesman R, Mosley TH, White L, Guðnason V, Debette S, Beiser AS, Seshadri S, Ikram MA, Meirelles O, Tzourio C, Launer LJ. Antihypertensive medications and risk for incident dementia and Alzheimer's disease: a meta-analysis of individual participant data from prospective cohort studies. The Lancet Neurology 2019, 19: 61-70. PMID: 31706889, PMCID: PMC7391421, DOI: 10.1016/s1474-4422(19)30393-x.Peer-Reviewed Original ResearchConceptsBlood pressure strataAntihypertensive medicationsBlood pressureRisk of dementiaIndividual participant dataIncident dementiaAlzheimer's diseaseDementia eventsDrug classesAging Intramural Research ProgramHigh blood pressure strataProspective community-based studyStudy-specific effect estimatesParticipant dataSpecific antihypertensive medicationsAlzheimer's Drug Discovery FoundationNormal blood pressureProspective cohort studyEligible observational studiesHigh blood pressureClinical Alzheimer's diseaseBurden of diseaseCommunity-based studyFuture clinical guidelinesCommunity-dwelling adults
2018
O3‐11‐01: USE OF BLOOD PRESSURE–LOWERING DRUGS AND RISK OF INCIDENT DEMENTIA AND ALZHEIMER'S DISEASE IN OLDER PEOPLE WITH AND WITHOUT HIGH BLOOD PRESSURE: A META‐ANALYSIS OF INDIVIDUAL PARTICIPANT DATA FROM PROSPECTIVE COHORT STUDIES
Ding J, Davis-Plourde K, Sedaghat S, Tully P, Wang W, Windham B, Phillips C, Griswold M, White L, Gudnason V, Debette S, Seshadri S, Ikram M, Meirelles O, Tzourio C, Launer L, Group M. O3‐11‐01: USE OF BLOOD PRESSURE–LOWERING DRUGS AND RISK OF INCIDENT DEMENTIA AND ALZHEIMER'S DISEASE IN OLDER PEOPLE WITH AND WITHOUT HIGH BLOOD PRESSURE: A META‐ANALYSIS OF INDIVIDUAL PARTICIPANT DATA FROM PROSPECTIVE COHORT STUDIES. Alzheimer's & Dementia 2018, 14: p1045-p1046. DOI: 10.1016/j.jalz.2018.06.2831.Peer-Reviewed Original Research