Does volumetric measurement of cervical lymph nodes serve as an imaging biomarker for locoregional recurrence of oral squamous cell carcinoma?
Safi AF, Kauke M, Jung H, Timmer M, Borggrefe J, Persigehl T, Nickenig HJ, Zinser M, Maintz D, Kreppel M, Zöller J. Does volumetric measurement of cervical lymph nodes serve as an imaging biomarker for locoregional recurrence of oral squamous cell carcinoma? Journal Of Cranio-Maxillofacial Surgery 2018, 46: 1013-1018. PMID: 29709330, DOI: 10.1016/j.jcms.2018.04.001.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overBiomarkersCarcinoma, Squamous CellChemoradiotherapyFemaleHumansLymph NodesLymphatic MetastasisMaleMicrosurgeryMiddle AgedMouth NeoplasmsMultivariate AnalysisNeckNeck DissectionNeoadjuvant TherapyNeoplasm Recurrence, LocalPrognosisRetrospective StudiesRisk FactorsTomography, X-Ray ComputedConceptsOral squamous cell carcinomaLymph node volumeSquamous cell carcinomaLocoregional recurrenceN classificationCell carcinomaNode volumeInclusion criteriaComputed tomographyTreatment-naive oral squamous cell carcinomaIpsilateral lymph node metastasisBetter risk stratification toolsComprehensive neck dissectionPathological N classificationCervical lymph nodesNegative resection marginsRetrospective chart reviewRisk stratification toolLymph node metastasisPreoperative computed tomographyVolumetric measurementsT4b classificationUnresectable diseaseLocoregional failureNeoadjuvant chemoradiotherapyThe importance of lymph node ratio for patients with mandibular infiltration of oral squamous cell carcinoma
Safi AF, Kauke M, Grandoch A, Nickenig HJ, Zöller J, Kreppel M. The importance of lymph node ratio for patients with mandibular infiltration of oral squamous cell carcinoma. Journal Of Cranio-Maxillofacial Surgery 2018, 46: 1007-1012. PMID: 29709331, DOI: 10.1016/j.jcms.2018.03.021.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overCarcinoma, Squamous CellChemoradiotherapyFemaleHumansKaplan-Meier EstimateLymph Node ExcisionLymph NodesLymphatic MetastasisMaleMandibleMiddle AgedMouth NeoplasmsMultivariate AnalysisNeck DissectionNeoadjuvant TherapyNeoplasm InvasivenessNeoplasm Recurrence, LocalNeoplasm StagingPrognosisRetrospective StudiesRisk AssessmentConceptsOral squamous cell carcinomaSquamous cell carcinomaMandibular infiltrationLocoregional recurrenceCell carcinomaLymph nodesExclusion criteriaTreatment-naive oral squamous cell carcinomaImportance of lymphPathologic N classificationLymph node ratioPositive lymph nodesNegative resection marginsRetrospective chart reviewRisk stratification toolAssessment of prognosisConventional nodalT4b classificationUnresectable diseaseNeoadjuvant chemoradiotherapyPerioperative deathsSynchronous malignanciesChart reviewResection marginsClinicopathological characteristics