Analysis of clinicopathological risk factors for locoregional recurrence of oral squamous cell carcinoma – Retrospective analysis of 517 patients
Safi AF, Kauke M, Grandoch A, Nickenig HJ, Zöller JE, Kreppel M. Analysis of clinicopathological risk factors for locoregional recurrence of oral squamous cell carcinoma – Retrospective analysis of 517 patients. Journal Of Cranio-Maxillofacial Surgery 2017, 45: 1749-1753. PMID: 28823597, DOI: 10.1016/j.jcms.2017.07.012.Peer-Reviewed Original ResearchConceptsCervical lymph nodesClinicopathological risk factorsIndependent risk factorSignificant risk factorsLocoregional recurrenceRisk factorsLymph nodesMultivariate analysisExtracapsular spreadHistological gradingTreatment-naive oral squamous cell carcinomaPossible significant risk factorPositive cervical lymph nodesOral squamous cell carcinomaIndividualized therapy managementPositive lymph nodesNegative resection marginsOverall survival rateSquamous cell carcinomaBinary logistic regression analysisLogistic regression analysisImprovement of therapyMaxillofacial plastic surgeryClinicopathological factorsResection marginsThe importance of log odds of positive lymph nodes for locoregional recurrence in oral squamous cell carcinoma
Safi AF, Kauke M, Grandoch A, Nickenig HJ, Drebber U, Zöller J, Kreppel M. The importance of log odds of positive lymph nodes for locoregional recurrence in oral squamous cell carcinoma. Oral Oncology 2017, 72: 48-55. PMID: 28797461, DOI: 10.1016/j.oraloncology.2017.07.005.Peer-Reviewed Original ResearchConceptsPositive lymph nodesOral squamous cell carcinomaSquamous cell carcinomaLymph node ratioLocoregional recurrenceLymph nodesCell carcinomaTreatment-naive oral squamous cell carcinomaNode ratioLog oddsIndependent indicatorPathologic N classificationPathologic T classificationRetrospective chart reviewMultiple cancer sitesConventional nodalT4b classificationUnresectable diseaseExtracapsular spreadNeoadjuvant chemoradiotherapyPerioperative deathsSynchronous malignanciesChart reviewNodal yieldN classification