2024
Rate of clinically significant red blood cell antibody seroconversion in pregnancy
Ding J, Abels E, Jacobs J, Culhane J, Lundsberg L, Partridge C, Denoble A, Kohari K. Rate of clinically significant red blood cell antibody seroconversion in pregnancy. The Journal Of Maternal-Fetal & Neonatal Medicine 2024, 37: 2419370. PMID: 39462637, DOI: 10.1080/14767058.2024.2419370.Peer-Reviewed Original ResearchConceptsNeonatal intensive care unitAdvanced maternal ageAssociated with seroconversionClinically significant antibodiesAntibody screeningNeonatal outcomesIncreasing gravidityAntibody seroconversionInitial hemoglobinMaternal ageSignificant antibodiesAntibody statusNeonatal intensive care unit admissionCohort studyClinically significant RBC antibodiesAnti-CUnexplained fetal lossPositive antibody screenNegative antibody screenCases of stillbirthRetrospective cohort studyIntensive care unitWilcoxon rank-sumMaternal antibody statusPostnatal transfusion
2020
Coronavirus disease 2019 pregnancy outcomes in a racially and ethnically diverse population
Grechukhina O, Greenberg V, Lundsberg LS, Deshmukh U, Cate J, Lipkind HS, Campbell KH, Pettker CM, Kohari KS, Reddy UM. Coronavirus disease 2019 pregnancy outcomes in a racially and ethnically diverse population. American Journal Of Obstetrics & Gynecology MFM 2020, 2: 100246. PMID: 33047100, PMCID: PMC7539936, DOI: 10.1016/j.ajogmf.2020.100246.Peer-Reviewed Original ResearchMeSH KeywordsAdultCommunicable Disease ControlComorbidityCOVID-19COVID-19 TestingEthnicityFemaleHealth Status DisparitiesHospitalizationHumansInfant, NewbornNew YorkObstetrics and Gynecology Department, HospitalPregnancyPregnancy Complications, InfectiousPregnancy OutcomePremature BirthRisk AssessmentRisk FactorsSARS-CoV-2ConceptsCoronavirus disease 2019Severe acute respiratory syndrome coronavirusAcute respiratory syndrome coronavirusSevere diseaseDisease 2019Pregnancy outcomesPositive test resultsClinical coursePostpartum womenRisk factorsHispanic ethnicityHispanic womenSevere acute respiratory syndrome coronavirus 2Coronavirus disease 2019 courseAcute respiratory syndrome coronavirus 2Severe coronavirus disease 2019Respiratory syndrome coronavirus 2Severe acute respiratory syndrome 2Effect of comorbidityWorse clinical courseC-reactive proteinSyndrome coronavirus 2Hypertensive disordersMedical comorbiditiesObese women
2018
Cesarean Scar Pregnancy, Incidence, and Recurrence
Grechukhina O, Deshmukh U, Fan L, Kohari K, Abdel-Razeq S, Bahtiyar MO, Sfakianaki AK. Cesarean Scar Pregnancy, Incidence, and Recurrence. Obstetrics And Gynecology 2018, 132: 1285-1295. PMID: 30303911, DOI: 10.1097/aog.0000000000002940.Peer-Reviewed Original ResearchMeSH KeywordsAbortifacient Agents, NonsteroidalAdultCesarean SectionCicatrixCombined Modality TherapyCurettageFemaleHumansHysteroscopyMethotrexatePotassium ChloridePregnancyPregnancy RatePregnancy, EctopicRecurrenceTertiary Care CentersUterine Artery EmbolizationUterine Balloon TamponadeWatchful WaitingYoung AdultConceptsCesarean scar pregnancyScar pregnancySubsequent pregnancy outcomeLocal methotrexatePregnancy outcomesTreatment modalitiesRecurrent cesarean scar pregnancyBilateral uterine artery embolizationElectronic medical record reviewYale-New Haven HospitalSubsequent spontaneous conceptionViable intrauterine pregnancyPrior cesarean deliveryMedical record reviewTime of diagnosisUterine artery embolizationPotassium chloride injectionFetal cardiac activityProducts of conceptionIntrauterine pregnancyPregnancy characteristicsSystemic methotrexateExpectant managementMethotrexate therapyArtery embolization
2017
A Randomized Trial of Foley Balloon Induction of Labor Trial in Multiparas (FIAT-M)
Connolly KA, Kohari KS, Factor SH, Rekawek P, Miller MR, Smilen BS, Stone JL, Bianco AT. A Randomized Trial of Foley Balloon Induction of Labor Trial in Multiparas (FIAT-M). American Journal Of Perinatology 2017, 34: 1108-1114. PMID: 28651258, DOI: 10.1055/s-0037-1603994.Peer-Reviewed Original ResearchConceptsInduction of laborComposite neonatal outcomeNeonatal outcomesPostpartum hemorrhageFoley balloonMultiparous womenUnexplained vaginal bleedingLength of laborMode of deliveryHospital stayTreat basisUterine surgeryVaginal bleedingBaseline characteristicsLabor inductionSecondary outcomesBlood lossCesarean deliveryChart reviewLatex allergyPrimary outcomeVaginal deliveryMedian timeRandomized trialsVertex presentation
2016
Mitochondrial gene expression profiles are associated with intrahepatic cholestasis of pregnancy
Mella MT, Kohari K, Jones R, Peña J, Ferrara L, Stone J, Lambertini L. Mitochondrial gene expression profiles are associated with intrahepatic cholestasis of pregnancy. Placenta 2016, 45: 16-23. PMID: 27577705, DOI: 10.1016/j.placenta.2016.07.002.Peer-Reviewed Original ResearchConceptsOxidative stress statusIntrahepatic cholestasisHepatic bile acid accumulationHigher maternal serum levelsMaternal serum levelsSpontaneous preterm birthNon-pregnant stateBile acid levelsBile acid concentrationsBile acid accumulationStress statusPathophysiology of ICPOxidative stress ratePreterm birthClinical courseFetal demiseSerum levelsFetal effectsPregnant womenHigh oxidative stressReal-time PCRLong-term effectsMitochondrial activityPlacenta samplesBile acidsA randomized trial of Foley balloon induction of labor trial in nulliparas (FIAT-N)
Connolly KA, Kohari KS, Rekawek P, Smilen BS, Miller MR, Moshier E, Factor SH, Stone JL, Bianco AT. A randomized trial of Foley balloon induction of labor trial in nulliparas (FIAT-N). American Journal Of Obstetrics And Gynecology 2016, 215: 392.e1-392.e6. PMID: 27018464, DOI: 10.1016/j.ajog.2016.03.034.Peer-Reviewed Original ResearchConceptsComposite neonatal outcomeFoley balloonNeonatal outcomesNulliparous womenBlood lossVaginal deliveryPostpartum hemorrhageSequential groupUnexplained vaginal bleedingInduction of laborMode of deliveryUterine surgeryTreat basisUnfavorable cervixVaginal bleedingBaseline characteristicsCesarean deliveryChart reviewSecondary outcomesLatex allergyPrimary outcomeVertex presentationGestational ageSingle institutionSingleton fetuses