2024
Medicare Coverage and Patient Out-of-Pocket Costs for Cardiovascular-Kidney-Metabolic Medications
Young G, Bansal K, Riello R, Clark K, Dhruva S, Faridi K, Desai N. Medicare Coverage and Patient Out-of-Pocket Costs for Cardiovascular-Kidney-Metabolic Medications. JAMA Network Open 2024, 7: e2412437. PMID: 38771578, PMCID: PMC11109768, DOI: 10.1001/jamanetworkopen.2024.12437.Peer-Reviewed Original Research
2023
Electronic Health Record Embedded Strategies for Improving Care of Patients With Heart Failure
Fuery M, Kadhim B, Samsky M, Freeman J, Clark K, Desai N, Wilson F, Ahmed T, Ahmad T. Electronic Health Record Embedded Strategies for Improving Care of Patients With Heart Failure. Current Heart Failure Reports 2023, 20: 280-286. PMID: 37552356, DOI: 10.1007/s11897-023-00614-0.Peer-Reviewed Original ResearchConceptsHeart failure patientsFailure patientsElectronic health recordsEHR alertClinical trialsRandomized clinical trialsCare of patientsQuality of careHeart failureClinician satisfactionRandomized fashionRecent FindingsTherePatientsUnmet needPatient careClinical decisionEvidence-based decisionsFuture interventionsCareHealth recordsTrialsCliniciansInterventionFindingsThere
2022
Moving Toward “Precision” Medicine: Can We Tailor Diabetes Therapy to Patients’ Differential Risks of Future Cardiovascular Disease?
Clark K, Morris A. Moving Toward “Precision” Medicine: Can We Tailor Diabetes Therapy to Patients’ Differential Risks of Future Cardiovascular Disease? Journal Of Cardiac Failure 2022, 29: 255-257. PMID: 36529315, DOI: 10.1016/j.cardfail.2022.12.002.Peer-Reviewed Original ResearchContemporary US Trends In Heart Transplantation And LVAD Index Hospitalizations: Volumes Increase, Utilization And Cost Vary Over Time, 2015-2018
Clark K, Reinhardt S, Chouairi F, Miller E, Kay B, Fuery M, Guha A, Ahmad T, Desai N. Contemporary US Trends In Heart Transplantation And LVAD Index Hospitalizations: Volumes Increase, Utilization And Cost Vary Over Time, 2015-2018. Journal Of Cardiac Failure 2022, 28: s65. DOI: 10.1016/j.cardfail.2022.03.165.Peer-Reviewed Original ResearchLength of stayHeart transplantationHospital mortalityIndex hospitalizationLVAD implantationLonger median LOSMedian LOSLonger LOSPost-discharge utilizationNational Inpatient SampleHospitalization volumeInpatient mortalityHispanic patientsAsian patientsInpatient SampleHospitalizationMortalityStudy periodUS trendsPatientsTransplantationAdmissionLVADImplantationHigh percentage
2021
Moving the Field Forward: Untangling the Impact of Frailty on Patients With Advanced Heart Failure and on Prognosticating Outcomes
Clark KAA, Nanna MG. Moving the Field Forward: Untangling the Impact of Frailty on Patients With Advanced Heart Failure and on Prognosticating Outcomes. Journal Of Cardiac Failure 2021, 28: 775-777. PMID: 34936895, PMCID: PMC9106896, DOI: 10.1016/j.cardfail.2021.12.006.Peer-Reviewed Original ResearchTrends and Outcomes of Cardiac Transplantation in the Lowest Urgency Candidates
Fuery MA, Chouairi F, Natov P, Bhinder J, Rose Chiravuri M, Wilson L, Clark KA, Reinhardt SW, Mullan C, Miller PE, Davis RP, Rogers JG, Patel CB, Sen S, Geirsson A, Anwer M, Desai N, Ahmad T. Trends and Outcomes of Cardiac Transplantation in the Lowest Urgency Candidates. Journal Of The American Heart Association 2021, 10: e023662. PMID: 34743559, PMCID: PMC9075266, DOI: 10.1161/jaha.121.023662.Peer-Reviewed Original ResearchConceptsLow-urgency patientsHigh-urgency patientsUrgency patientsCardiac transplantationAllocation system changeLonger waitlist timesOrgan Sharing databaseTime of transplantationCardiac transplantation candidatesNew allocation systemBaseline recipientPosttransplantation outcomesPosttransplantation survivalAdditional comorbiditiesClinical characteristicsConclusions PatientsHepatitis CIschemic timeTransplantation candidatesSharing databaseWaitlist timeWaitlist survivalUnited NetworkRetrospective analysisPatientsTrends in transcatheter and surgical aortic valve replacement in the United States, 2008-2018
Clark KA, Chouairi F, Kay B, Reinhardt SW, Miller PE, Fuery M, Mullan CW, Guha A, Ahmad T, Desai NR. Trends in transcatheter and surgical aortic valve replacement in the United States, 2008-2018. American Heart Journal 2021, 243: 87-91. PMID: 34571040, DOI: 10.1016/j.ahj.2021.03.017.Peer-Reviewed Original ResearchEvaluation of Racial and Ethnic Disparities in Cardiac Transplantation
Chouairi F, Fuery M, Clark KA, Mullan CW, Stewart J, Caraballo C, Clarke J, Sen S, Guha A, Ibrahim NE, Cole RT, Holaday L, Anwer M, Geirsson A, Rogers JG, Velazquez EJ, Desai NR, Ahmad T, Miller PE. Evaluation of Racial and Ethnic Disparities in Cardiac Transplantation. Journal Of The American Heart Association 2021, 10: e021067. PMID: 34431324, PMCID: PMC8649228, DOI: 10.1161/jaha.120.021067.Peer-Reviewed Original ResearchConceptsWhite patientsHispanic patientsBlack patientsCardiac transplantationHeart transplantationHigh riskEthnic disparitiesAdult heart recipientsAllocation system changePost-transplant deathPost-transplant mortalityOrgan Sharing databasePost-transplantation deathNew allocation systemHeart recipientsDiabetes mellitusRenal diseaseSharing databaseTransplantation ratesUnited NetworkContemporary outcomesPatientsTransplantationDonor characteristicsStudy periodMechanical ventilation at the time of heart transplantation and associations with clinical outcomes
Miller PE, Mullan CW, Chouairi F, Sen S, Clark KA, Reinhardt S, Fuery M, Anwer M, Geirsson A, Formica R, Rogers JG, Desai NR, Ahmad T. Mechanical ventilation at the time of heart transplantation and associations with clinical outcomes. European Heart Journal Acute Cardiovascular Care 2021, 10: 843-851. PMID: 34389855, PMCID: PMC8557439, DOI: 10.1093/ehjacc/zuab063.Peer-Reviewed Original ResearchConceptsHeart transplantationMechanical ventilationSingle-organ heart transplantationMedian waitlist timeOrgan Sharing databaseTime of transplantationMultivariable logistic regressionMultivariable adjustmentWaitlist timeClinical outcomesSharing databasePoor outcomeVentilated patientsUnited NetworkTemporary mechanical supportClinical acuityTransplantationPatientsPrevious dialysisLogistic regressionMortalityStrong associationReasonable outcomesOutcomesAssociationNational Trends in the Burden of Atrial Fibrillation During Hospital Admissions for Heart Failure
Reinhardt SW, Chouairi F, Miller PE, Clark KAA, Kay B, Fuery M, Guha A, Freeman JV, Ahmad T, Desai NR, Friedman DJ. National Trends in the Burden of Atrial Fibrillation During Hospital Admissions for Heart Failure. Journal Of The American Heart Association 2021, 10: e019412. PMID: 34013736, PMCID: PMC8483517, DOI: 10.1161/jaha.120.019412.Peer-Reviewed Original ResearchConceptsReduced ejection fractionComorbid atrial fibrillationHeart failureAtrial fibrillationEjection fractionHospital mortalityHF hospitalizationBackground Heart failureConclusion Atrial fibrillationWhite individualsNational Inpatient SampleMedian hospital chargesMore comorbiditiesComorbid hypertensionHF admissionsHF outcomesPatient demographicsDiabetes mellitusHospital admissionHospital chargesInpatient SampleVascular diseaseHospitalizationPatientsMortality
2017
Concurrent Central Venous Stent and Central Venous Access Device Placement Does Not Compromise Stent Patency or Catheter Function in Patients with Malignant Central Venous Obstruction
Clark K, Chick J, Reddy S, Shin B, Nadolski G, Clark T, Trerotola S. Concurrent Central Venous Stent and Central Venous Access Device Placement Does Not Compromise Stent Patency or Catheter Function in Patients with Malignant Central Venous Obstruction. Journal Of Vascular And Interventional Radiology 2017, 28: 602-607. PMID: 28238580, DOI: 10.1016/j.jvir.2016.12.1222.Peer-Reviewed Original ResearchConceptsCentral venous access devicesCentral venous obstructionCatheter functionStent patencyStent stenosisVenous obstructionClinical symptomsVenous stentsType of CVADCentral venous access device placementControl groupSuperior vena cava syndromeRecurrent clinical symptomsVena cava syndromeVenous access devicesCVAD placementStent revisionSymptomatic stenosisConsecutive patientsPatientsMalignant compressionStenosisPatencyDevice placementClinical performance
2015
Clinician Perception of the Effectiveness of an Automated Early Warning and Response System for Sepsis in an Academic Medical Center
Guidi J, Clark K, Upton M, Faust H, Umscheid C, Lane-Fall M, Mikkelsen M, Schweickert W, Vanzandbergen C, Betesh J, Tait G, Hanish A, Smith K, Feeley D, Fuchs B. Clinician Perception of the Effectiveness of an Automated Early Warning and Response System for Sepsis in an Academic Medical Center. Annals Of The American Thoracic Society 2015, 12: 1514-1519. PMID: 26288388, DOI: 10.1513/annalsats.201503-129oc.Peer-Reviewed Original ResearchConceptsMost patientsClinicians' perceptionsMedical CenterLarge tertiary referral medical centerTertiary referral medical centerReferral medical centerAcademic medical centerSevere sepsisBedside cliniciansAdditional interventionsClose monitoringMinority of respondersPatient careCliniciansPeriod 1 monthSepsisPatientsOne-thirdResponse systemSuch alertsProvidersNursesRespondersCareMonths
2013
Angina Pectoris or Myocardial Infarctions, Pulmonary Arteriovenous Malformations, Hereditary Hemorrhagic Telangiectasia, and Paradoxical Emboli
Clark K, Pyeritz R, Trerotola S. Angina Pectoris or Myocardial Infarctions, Pulmonary Arteriovenous Malformations, Hereditary Hemorrhagic Telangiectasia, and Paradoxical Emboli. The American Journal Of Cardiology 2013, 112: 731-734. PMID: 23707042, DOI: 10.1016/j.amjcard.2013.04.052.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAngina PectorisArteriovenous MalformationsChildChild, PreschoolEmbolism, ParadoxicalEmbolization, TherapeuticFemaleHumansMaleMiddle AgedMyocardial InfarctionMyocardial IschemiaPulmonary ArteryPulmonary VeinsRetrospective StudiesSelf ReportTelangiectasia, Hereditary HemorrhagicYoung AdultConceptsPulmonary arteriovenous malformationsParadoxical emboliHereditary hemorrhagic telangiectasiaCoronary arteryMyocardial infarctionArteriovenous malformationsHemorrhagic telangiectasiaSingle-center populationNormal coronary arteriesTransient ischemic attackCardiac ischemic eventsUntreated pulmonary arteriovenous malformationsSingle artery occlusionAutosomal dominant disorderCardiopulmonary symptomsIschemic attackChest painArtery occlusionIschemic eventsAngina pectorisCardiac catheterizationClinical complicationsVascular malformationsCardiac ischemiaPatients