Genomic Perspectives of Transcriptional Regulation in Forebrain Development
Nord AS, Pattabiraman K, Visel A, Rubenstein JL. Genomic Perspectives of Transcriptional Regulation in Forebrain Development. Neuron 2015, 85: 27-47. PMID: 25569346, PMCID: PMC4438709, DOI: 10.1016/j.neuron.2014.11.011.Peer-Reviewed Original ResearchConceptsCis-acting genomic elementsForebrain developmentGene expression statesGene expression programsAnalysis of chromatinGenomic regulatory mechanismsGenetic circuitryGenomic perspectiveExpression programsGenomic elementsTranscriptional regulationExpression statesHigher-order brain functionsTranscription factorsDNA modificationsGene expressionRegulatory mechanismsHuman neuropsychiatric disordersGenetic defectsCurrent knowledgeChromatinRecent progressEnhancerNeuropsychiatric disordersRegulation