2013
Increasing dietary protein selectively upregulates the DMT1 isoform that contains an iron responsive element
Thomas C, Yao G, O'Brien K, Kerstetter J, Insogna K. Increasing dietary protein selectively upregulates the DMT1 isoform that contains an iron responsive element. The FASEB Journal 2013, 27: lb284-lb284. DOI: 10.1096/fasebj.27.1_supplement.lb284.Peer-Reviewed Original ResearchIntestinal iron absorptionIron absorptionDietary proteinProtein dietMRNA expressionWhole-body iron homeostasisDuodenum of ratsDMT1 mRNA expressionBody iron homeostasisGenetic absenceExperimental animalsLevel of expressionResponsive elementBrush border membraneRatsIron-responsive elementRecent dataDietCritical regulatorIron homeostasisBorder membraneSignificant changesExpressionIron importerAnimals
2010
A High Protein Diet Induces Intestinal Iron Transporter Expression and Improves Iron Absorption in Rats
Cucchi C, Gaffney‐Stomberg E, Sun B, Kerstetter J, Insogna K. A High Protein Diet Induces Intestinal Iron Transporter Expression and Improves Iron Absorption in Rats. The FASEB Journal 2010, 24: 229.1-229.1. DOI: 10.1096/fasebj.24.1_supplement.229.1.Peer-Reviewed Original ResearchDietary proteinIron absorptionTransporter expressionHigh casein dietExpression of DMT1Iron transporter expressionFe absorptionVs. 5Kruskal-Wallis testMicroarray screenCasein dietMineral homeostasisLevel of expressionProtein dietRatsLittle dataDMT1 expressionQ-PCRDietBalance studiesExpressionHomeostasisGroupDMT1CYBRD1