Parathyroid Hormone Increases Circulating Levels of Fibronectin in Vivo: Modulating Effect of Ovariectomy*
Sun B, Mitnick M, Eielson C, Yao G, Paliwal I, Insogna K. Parathyroid Hormone Increases Circulating Levels of Fibronectin in Vivo: Modulating Effect of Ovariectomy*. Endocrinology 1997, 138: 3918-3924. DOI: 10.1210/en.138.9.3918.Peer-Reviewed Original ResearchResponse to PTHEffect of PTHHuman PTHCirculating levelsLevels of FNFN in vivoCultured fetal rat bonesAdult female Sprague-Dawley ratsFemale Sprague-Dawley ratsTreated with PTHVehicle infused groupFN productionEstrogen-deficient stateFetal rat bonesSignificant 2.4-fold increaseBlock bone resorptionSprague-Dawley ratsROS 17/2.8 cellsIn vitro studiesBisphosphonate APDEstrogen deficiencyAlzet minipumpsEstrogen withdrawalLevels in vivoBlunted response