Featured Publications
Arousal impacts distributed hubs modulating the integration of brain functional connectivity
Lee K, Horien C, O’Connor D, Garand-Sheridan B, Tokoglu F, Scheinost D, Lake EMR, Constable RT. Arousal impacts distributed hubs modulating the integration of brain functional connectivity. NeuroImage 2022, 258: 119364. PMID: 35690257, PMCID: PMC9341222, DOI: 10.1016/j.neuroimage.2022.119364.Peer-Reviewed Original ResearchDisruption, emergence and lateralization of brain network hubs in mesial temporal lobe epilepsy
Lee K, Khoo HM, Lina JM, Dubeau F, Gotman J, Grova C. Disruption, emergence and lateralization of brain network hubs in mesial temporal lobe epilepsy. NeuroImage Clinical 2018, 20: 71-84. PMID: 30094158, PMCID: PMC6070692, DOI: 10.1016/j.nicl.2018.06.029.Peer-Reviewed Original ResearchConceptsMesial temporal lobe epilepsyTemporal lobe epilepsyLobe epilepsyState functional MRIDefault mode networkHealthy controlsBrain network hubsConnector hubsAbnormal hippocampusMotor networkHippocampal networkBrain regionsSalience networkFunctional MRIEpilepsyEpileptic subjectsMode networkLateralizationBrain networksDefault modeAbnormalitiesPathological disruptionHub reorganizationFunctional networksDisruption
2021
An altered balance of integrated and segregated brain activity is a marker of cognitive deficits following sleep deprivation
Cross NE, Pomares FB, Nguyen A, Perrault AA, Jegou A, Uji M, Lee K, Razavipour F, Bin Ka’b Ali O, Aydin U, Benali H, Grova C, Dang-Vu TT. An altered balance of integrated and segregated brain activity is a marker of cognitive deficits following sleep deprivation. PLOS Biology 2021, 19: e3001232. PMID: 34735431, PMCID: PMC8568176, DOI: 10.1371/journal.pbio.3001232.Peer-Reviewed Original ResearchConceptsSleep-deprived stateSleep deprivationCortical networksFunctional magnetic resonance imaging (fMRI) scansLarge-scale cortical networksCognitive impairmentSleep-deprived brainNight of SDHomeostatic sleep pressureExecutive tasksCognitive performanceTask performanceCognitive changesRegular nightBrain activityCognitive functionCognitive deficitsNetwork integrationInformation processingSleep pressureCortical activityBidirectional effectsConnectivity changesInterindividual differencesNonrapid eye movement sleep
2016
SPARK: Sparsity-based analysis of reliable k-hubness and overlapping network structure in brain functional connectivity
Lee K, Lina JM, Gotman J, Grova C. SPARK: Sparsity-based analysis of reliable k-hubness and overlapping network structure in brain functional connectivity. NeuroImage 2016, 134: 434-449. PMID: 27046111, DOI: 10.1016/j.neuroimage.2016.03.049.Peer-Reviewed Original Research