Trajectory of blood pressure after initiating anti-calcitonin gene-related peptide treatment of migraine: a target trial emulation from the veterans health administration
Wang K, Fenton B, Dao V, Guirguis A, Anthony S, Skanderson M, Sico J. Trajectory of blood pressure after initiating anti-calcitonin gene-related peptide treatment of migraine: a target trial emulation from the veterans health administration. The Journal Of Headache And Pain 2023, 24: 108. PMID: 37582724, PMCID: PMC10426172, DOI: 10.1186/s10194-023-01640-y.Peer-Reviewed Original ResearchConceptsAnti-CGRP treatmentVeterans Health AdministrationBlood pressureBP changesHealth AdministrationDiastolic BP changesExacerbation of hypertensionNumber of antihypertensivesIncidence of hypertensionHigher healthcare utilizationSystolic BP changeKaplan-Meier curvesBlood pressure readingsGene-related peptideTarget trial emulationYears of treatmentBlood pressure regulationHigh-quality real-world evidenceReal-world evidenceMixed-effects Poisson modelsChronic migraine diagnosisInverse probability weightsAntihypertension medicationsAntihypertensive medicationsBaseline hypertension