2022
Triggering of myocardial infarction by heat exposure is modified by medication intake
Chen K, Dubrow R, Breitner S, Wolf K, Linseisen J, Schmitz T, Heier M, von Scheidt W, Kuch B, Meisinger C, Peters A, Schneider A. Triggering of myocardial infarction by heat exposure is modified by medication intake. Nature Cardiovascular Research 2022, 1: 727-731. PMID: 39196082, DOI: 10.1038/s44161-022-00102-z.Peer-Reviewed Original ResearchMyocardial infarctionEffect modificationMI riskPre-existing coronary heart diseaseAnti-platelet medicationCertain cardiovascular medicationsBeta-receptor blockersCoronary heart diseaseAcute myocardial infarctionHeat exposureCardiovascular medicationsOlder patientsYounger patientsMedication useMedication intakeHeart diseaseHigh prevalenceLow prevalenceMI casesMedicationsPatientsInfarctionSignificant differencesCHDPrevalence
2020
Hourly Exposure to Ultrafine Particle Metrics and the Onset of Myocardial Infarction in Augsburg, Germany
Chen K, Schneider A, Cyrys J, Wolf K, Meisinger C, Heier M, von Scheidt W, Kuch B, Pitz M, Peters A, Breitner S, Group F. Hourly Exposure to Ultrafine Particle Metrics and the Onset of Myocardial Infarction in Augsburg, Germany. Environmental Health Perspectives 2020, 128: 017003. PMID: 31939685, PMCID: PMC7015564, DOI: 10.1289/ehp5478.Peer-Reviewed Original ResearchConceptsMyocardial infarctionMI casesTime-stratified case-crossover analysisConditional logistic regressionInterquartile range increaseCase-crossover analysisTwo-pollutant modelsMI registryEpidemiological evidenceDifferent particle metricsCardiovascular diseaseMyocardial infractionSimilar associationLogistic regressionHourly air pollutionParticle metricsEffect estimatesHealth effectsExposure metricsIndependent effectsTransient exposureInfarctionAssociationExposureAerodynamic diameter
2019
Temporal variations in the triggering of myocardial infarction by air temperature in Augsburg, Germany, 1987–2014
Chen K, Breitner S, Wolf K, Hampel R, Meisinger C, Heier M, von Scheidt W, Kuch B, Peters A, Schneider A, Peters A, Schulz H, Schwettmann L, Leidl R, Heier M, Strauch K. Temporal variations in the triggering of myocardial infarction by air temperature in Augsburg, Germany, 1987–2014. European Heart Journal 2019, 40: 1600-1608. PMID: 30859207, DOI: 10.1093/eurheartj/ehz116.Peer-Reviewed Original ResearchConceptsMyocardial infarctionMI riskCases of MIRisk of MITime-stratified case-crossover analysisPopulation susceptibilityCase-crossover analysisArea of AugsburgCoronary deathDiabetes mellitusNon-significant declineSubgroup analysisRelative riskLag non-linear modelShort-term exposureMI eventsEnvironmental triggersInfarctionRiskFuture studiesSocioeconomic settingsAssociationExposureSusceptibility