2023
The mortality burden of extreme heat in Connecticut: A time series analysis
Goddard E, Lin C, Ma Y, Chen K. The mortality burden of extreme heat in Connecticut: A time series analysis. PLOS Climate 2023, 2: e0000164. DOI: 10.1371/journal.pclm.0000164.Peer-Reviewed Original ResearchMortality burdenGlobal Burden of Disease 2019 studyClimate changeHealth impact estimatesStatistically significant positive associationTemperature percentileQuasi-Poisson regressionSignificant positive associationAll-cause mortalityNegative health effectsTime series analysisLong-term trendsGlobal burdenHeat-related mortalityRelative riskEpidemiological evidenceGeneralized linear modelClimate change planningSeasonal deathsHealth impactsPublic healthPositive associationRegional policy decisionsWarm seasonHealth
2021
Ambient carbon monoxide and daily mortality: a global time-series study in 337 cities
Chen K, Breitner S, Wolf K, Stafoggia M, Sera F, Vicedo-Cabrera AM, Guo Y, Tong S, Lavigne E, Matus P, Valdés N, Kan H, Jaakkola JJK, Ryti NRI, Huber V, Scortichini M, Hashizume M, Honda Y, Nunes B, Madureira J, Holobâcă IH, Fratianni S, Kim H, Lee W, Tobias A, Íñiguez C, Forsberg B, Åström C, Ragettli MS, Guo YL, Chen BY, Li S, Milojevic A, Zanobetti A, Schwartz J, Bell ML, Gasparrini A, Schneider A. Ambient carbon monoxide and daily mortality: a global time-series study in 337 cities. The Lancet Planetary Health 2021, 5: e191-e199. PMID: 33838734, DOI: 10.1016/s2542-5196(21)00026-7.Peer-Reviewed Original ResearchConceptsExposure-response curvesAmbient carbon monoxideTotal mortalityDaily mortalityUK Medical Research CouncilElevated mortality riskLarge epidemiological investigationsPotential publication biasMedical Research CouncilCity-specific associationsMeta-analytical modelsShort-term associationsQuasi-Poisson distributionCurrent air quality guidelinesEpidemiological evidenceMortality riskDaily total mortalityShort-term exposurePublication biasSignificant associationEpidemiological investigationsTime-series studyGreater riskMortalityMortality data
2020
Hourly Exposure to Ultrafine Particle Metrics and the Onset of Myocardial Infarction in Augsburg, Germany
Chen K, Schneider A, Cyrys J, Wolf K, Meisinger C, Heier M, von Scheidt W, Kuch B, Pitz M, Peters A, Breitner S, Group F. Hourly Exposure to Ultrafine Particle Metrics and the Onset of Myocardial Infarction in Augsburg, Germany. Environmental Health Perspectives 2020, 128: 017003. PMID: 31939685, PMCID: PMC7015564, DOI: 10.1289/ehp5478.Peer-Reviewed Original ResearchConceptsMyocardial infarctionMI casesTime-stratified case-crossover analysisConditional logistic regressionInterquartile range increaseCase-crossover analysisTwo-pollutant modelsMI registryEpidemiological evidenceDifferent particle metricsCardiovascular diseaseMyocardial infractionSimilar associationLogistic regressionHourly air pollutionParticle metricsEffect estimatesHealth effectsExposure metricsIndependent effectsTransient exposureInfarctionAssociationExposureAerodynamic diameter