2024
Post-traumatic stress and future substance use outcomes: leveraging antecedent factors to stratify risk
Garrison-Desany H, Meyers J, Linnstaedt S, House S, Beaudoin F, An X, Zeng D, Neylan T, Clifford G, Jovanovic T, Germine L, Bollen K, Rauch S, Haran J, Storrow A, Lewandowski C, Musey P, Hendry P, Sheikh S, Jones C, Punches B, Swor R, Gentile N, Hudak L, Pascual J, Seamon M, Harris E, Pearson C, Peak D, Domeier R, Rathlev N, O’Neil B, Sergot P, Sanchez L, Bruce S, Joormann J, Harte S, McLean S, Koenen K, Denckla C. Post-traumatic stress and future substance use outcomes: leveraging antecedent factors to stratify risk. Frontiers In Psychiatry 2024, 15: 1249382. PMID: 38525258, PMCID: PMC10957776, DOI: 10.3389/fpsyt.2024.1249382.Peer-Reviewed Original ResearchPost-traumatic stress disorder symptomsPost-traumatic stress disorderCannabis usePhysical healthSubstance useSelf-rated physical healthPTSD symptomsAlcohol useAssociation of post-traumatic stress disorderFuture substancePoisson generalized estimating equationsProspective cohort of adultsSelf-reported PTSD symptomsPrevalent substance useAssociated with PTSD symptomsCohort of adultsPost-traumatic stressFuture substance useAssociated with tobaccoQuantity of tobaccoTobacco usePsychosocial characteristicsEffect modifiersEmergency departmentStress disorder
2023
Structural inequities contribute to racial/ethnic differences in neurophysiological tone, but not threat reactivity, after trauma exposure
Harnett N, Fani N, Carter S, Sanchez L, Rowland G, Davie W, Guzman C, Lebois L, Ely T, van Rooij S, Seligowski A, Winters S, Grasser L, Musey P, Seamon M, House S, Beaudoin F, An X, Zeng D, Neylan T, Clifford G, Linnstaedt S, Germine L, Bollen K, Rauch S, Haran J, Storrow A, Lewandowski C, Hendry P, Sheikh S, Jones C, Punches B, Swor R, Hudak L, Pascual J, Harris E, Chang A, Pearson C, Peak D, Merchant R, Domeier R, Rathlev N, Bruce S, Miller M, Pietrzak R, Joormann J, Barch D, Pizzagalli D, Harte S, Elliott J, Kessler R, Koenen K, McLean S, Jovanovic T, Stevens J, Ressler K. Structural inequities contribute to racial/ethnic differences in neurophysiological tone, but not threat reactivity, after trauma exposure. Molecular Psychiatry 2023, 28: 2975-2984. PMID: 36725899, PMCID: PMC10615735, DOI: 10.1038/s41380-023-01971-x.Peer-Reviewed Original ResearchConceptsPost-traumatic stress disorderAmygdala connectivityAmygdala reactivityTrauma exposurePrefrontal cortexPTSD symptomsDorsal anterior cingulate cortexAnterior cingulate cortexFunctional magnetic resonance imagingMagnetic resonance imagingGreater amygdala connectivityDorsolateral prefrontal cortexSymptoms 3Trauma outcomesSkin conductance levelCingulate cortexEthnic groupsEthnic disparitiesResonance imagingMultisite longitudinal studyStress disorderTwo weeksEthnic variabilityWhite individualsBlack participants