2006
Microarray-Assisted Pathway Analysis Identifies Mitogen-Activated Protein Kinase Signaling as a Mediator of Resistance to the Green Tea Polyphenol Epigallocatechin 3-Gallate in Her-2/neu–Overexpressing Breast Cancer Cells
Guo S, Lu J, Subramanian A, Sonenshein GE. Microarray-Assisted Pathway Analysis Identifies Mitogen-Activated Protein Kinase Signaling as a Mediator of Resistance to the Green Tea Polyphenol Epigallocatechin 3-Gallate in Her-2/neu–Overexpressing Breast Cancer Cells. Cancer Research 2006, 66: 5322-5329. PMID: 16707458, DOI: 10.1158/0008-5472.can-05-4287.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnticarcinogenic AgentsCatechinCell AdhesionCell Growth ProcessesDexamethasoneDrug Resistance, NeoplasmEnzyme ActivationMammary Neoplasms, ExperimentalMAP Kinase Signaling SystemMiceMitogen-Activated Protein KinasesNF-kappa BOligonucleotide Array Sequence AnalysisPhosphorylationReceptor, ErbB-2RNA, Messenger
2003
An adenosine analogue, IB-MECA, down-regulates estrogen receptor alpha and suppresses human breast cancer cell proliferation.
Lu J, Pierron A, Ravid K. An adenosine analogue, IB-MECA, down-regulates estrogen receptor alpha and suppresses human breast cancer cell proliferation. Cancer Research 2003, 63: 6413-23. PMID: 14559831.Peer-Reviewed Original ResearchConceptsEstrogen receptor alphaIB-MECAMCF-7 cellsReceptor alphaHuman breast cancer cell proliferationBreast cancer cell proliferationDifferent adenosine analoguesHuman breast cancer cell line MCF-7Overexpression of ERalphaBreast cancer cell line MCF-7Breast cancer treatmentCancer cell line MCF-7Adenosine analoguesHs578T cellsCancer cell proliferationCell line MCF-7Breast cancer cell typesDifferent breast cancer cell typesCancer cell typesT cellsDrug treatmentN-methyluronamideSelective agonistZR-75Positive cells