MicroRNA Expression Profiling Identifies Activated B Cell Status in Chronic Lymphocytic Leukemia Cells
Li S, Moffett HF, Lu J, Werner L, Zhang H, Ritz J, Neuberg D, Wucherpfennig KW, Brown JR, Novina CD. MicroRNA Expression Profiling Identifies Activated B Cell Status in Chronic Lymphocytic Leukemia Cells. PLOS ONE 2011, 6: e16956. PMID: 21408091, PMCID: PMC3050979, DOI: 10.1371/journal.pone.0016956.Peer-Reviewed Original ResearchConceptsB cell statusChronic lymphocytic leukemiaCLL cellsB cellsCpG activationChronic lymphocytic leukemia cellsActivated B cellsLymphocytic leukemia cellsCell statusClinical courseFirst therapyExpression profiling identifiesLymphocytic leukemiaNormal donorsUnmutated statusMiR-155MiR-223MiR-181bMiR-29cMiR-181aLeukemia cellsMiR-103Untransformed B cellsRecent dataProfiling identifies