Targeting glucose metabolism in cancer: a new class of agents for loco-regional and systemic therapy of liver cancer and beyond?
Savic LJ, Chapiro J, Duwe G, Geschwind J. Targeting glucose metabolism in cancer: a new class of agents for loco-regional and systemic therapy of liver cancer and beyond? Hepatic Oncology 2015, 3: 19-28. PMID: 26989470, PMCID: PMC4792180, DOI: 10.2217/hep.15.36.Peer-Reviewed Original ResearchIntra-arterial therapyHepatocellular carcinomaCancer-related deathUnresectable diseaseCancer cell metabolismSystemic therapyTherapeutic optionsTumor controlPrevalent cancerLiver cancerGlucose metabolismAntiglycolytic agentsTumor growthSystemic toxicitySelective anticancer therapyTherapyAnticancer therapyCancerNew targetsWarburg effectMolecular featuresAntiglycolytic drugsCell metabolismDelivery methodsMetabolism