Monoclonal Antibodies Against LipL32, The Major Outer Membrane Protein of Pathogenic Leptospira Production, Characterization, and Testing in Diagnostic Applications
Fernandes C, Seixas FK, Coutinho ML, Vasconcellos F, Seyffert N, Croda J, McBride AJ, Ko AI, Dellagostin OA, Aleixo J. Monoclonal Antibodies Against LipL32, The Major Outer Membrane Protein of Pathogenic Leptospira Production, Characterization, and Testing in Diagnostic Applications. Monoclonal Antibodies In Immunodiagnosis And Immunotherapy 2007, 26: 35-41. PMID: 17316084, DOI: 10.1089/hyb.2006.033.Peer-Reviewed Original ResearchConceptsMembrane proteinsNative proteinMajor Outer Membrane ProteinOuter membrane lipoproteinOuter Membrane ProteinOuter membrane proteinsOuter membraneMembrane lipoproteinWide antigenic diversityBacterial cellsLeptospiral cellsIntact bacteriaProteinProtein enzyme-linked immunosorbent assayAntigenic diversityPolymerase chain reaction amplificationHeat-treated cellsMonoclonal antibodiesRecombinant formChain reaction amplificationEnzyme-linked immunosorbent assayFluorescein isothiocyanateCellsMurine monoclonal antibodiesPathogenic Leptospira