2024
Seroprevalence of Treponema pallidum infection among high-risk populations from Brazil
Queiroz J, Barbosa M, Perez E, da Silva B, de Souza G, Gonçalves C, Croda J, Simionatto S. Seroprevalence of Treponema pallidum infection among high-risk populations from Brazil. Acta Tropica 2024, 256: 107255. PMID: 38761835, DOI: 10.1016/j.actatropica.2024.107255.Peer-Reviewed Original ResearchConceptsSexually transmitted infectionsHigh-risk groupCases of syphilisFactors associated with syphilisPregnant womenHistory of sexually transmitted infectionsPublic health strategiesHealthy populationSignificant public health concernPrevent future complicationsHigh risk of infectionHigh-risk populationPublic health concernHealth strategiesParticipant demographicsCross-sectional oneRisk of infectionVulnerable populationsFuture complicationsPLHIVTreatment outcomesHealth concernHigh riskSyphilisInfectionThe impact of sputum quality on Xpert positivity in active case-finding for TB
Oliveira da Silva B, Salindri A, Gonçalves T, Cunha E, da Silva Santos A, dos Santos P, Lemes I, Silva D, da Silva Oliveira V, Croda J, de Oliveira R, Andrews J. The impact of sputum quality on Xpert positivity in active case-finding for TB. The International Journal Of Tuberculosis And Lung Disease 2024, 28: 29-36. PMID: 38178289, DOI: 10.5588/ijtld.23.0244.Peer-Reviewed Original ResearchMeSH KeywordsCross-Sectional StudiesHumansMycobacterium tuberculosisSensitivity and SpecificitySputumTuberculosis, PulmonaryConceptsSputum qualityXpert-positiveCase findingChest X-rayLog-binomial regressionCross-sectional analysisMass screening programmeActive case findingCurrent smokingParticipant characteristicsScreening programmeSymptom screeningStandardised questionnaireSpot sputum samplesBlood-stained sputumAbnormal chest radiographBinomial regressionCAD4TBSputum appearanceMucopurulent sputumXpert testingSputum samplesClinical characteristicsSalivary specimensChest radiographs
2023
Spread of Mycobacterium tuberculosis in Southern Brazilian persons deprived of liberty: a molecular epidemiology study
Busatto C, Possuelo L, Bierhals D, de Oliveira C, de Souza M, Fanfa D, Barreto É, Schwarzbold P, Von Groll A, Portugal I, Perdigão J, Croda J, Andrews J, da Silva P, Ramis I. Spread of Mycobacterium tuberculosis in Southern Brazilian persons deprived of liberty: a molecular epidemiology study. European Journal Of Clinical Microbiology & Infectious Diseases 2023, 42: 297-304. PMID: 36701032, DOI: 10.1007/s10096-023-04546-4.Peer-Reviewed Original ResearchMeSH KeywordsBrazilCross-Sectional StudiesGenotypeHumansMinisatellite RepeatsMolecular EpidemiologyMycobacterium tuberculosisPhylogenyTuberculosisConceptsAnti-TB drug resistanceM. tuberculosisTB control programsCross-sectional studyM. tuberculosis strainsMolecular epidemiology studiesTB burdenLAM strainsTuberculosis strainsEpidemiology studiesDrug resistanceMycobacterium tuberculosisCentral laboratoryTranslational researchTuberculosisCommon strainControl programsPDLMolecular characterizationHaarlemImproved strategiesPersons
2021
Epidemiological study in Brazilian women highlights that syphilis remains a public health problem
dos Santos Barbosa M, de Lima L, Ribeiro S, Croda J, de Sá Queiroz J, Ortolani L, Negrão F, Souza E, da Silva K, de Souza R, Simionatto S. Epidemiological study in Brazilian women highlights that syphilis remains a public health problem. Revista Do Instituto De Medicina Tropical De São Paulo 2021, 63: e4. PMID: 33533807, PMCID: PMC7845940, DOI: 10.1590/s1678-9946202163004.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBrazilCitiesCondomsCross-Sectional StudiesFemaleHumansMiddle AgedPrevalencePublic HealthSeroepidemiologic StudiesSyphilisTreponema pallidumUnsafe SexConceptsT. pallidum infectionSexual partnersPrimary health care unitsContinuous surveillance studiesGlobal public health concernHistory of STICross-sectional studyHigher prevalence ratioPublic health problemMultiple sexual partnersPopulation-based sampleHealth care unitsPublic health concernCommitment of patientsCare unitMultivariable analysisNeonatal deathPrevalence ratiosSyphilis testingSyphilis screeningReproductive ageRisk factorsBlood samplesEpidemiological studiesSurveillance study
2020
Gestational outcomes in women infected by Zika virus during pregnancy in Mato Grosso do Sul, Brazil: A cross-sectional study
Sousa I, Souza C, Barbosa M, Croda J, Gonçalves C, Bernardes S, Marchioro S. Gestational outcomes in women infected by Zika virus during pregnancy in Mato Grosso do Sul, Brazil: A cross-sectional study. International Journal Of Infectious Diseases 2020, 98: 359-365. PMID: 32619757, DOI: 10.1016/j.ijid.2020.06.084.Peer-Reviewed Original ResearchConceptsCongenital Zika syndromeZIKV infectionCross-sectional studyGestational outcomesZika virusNormal-appearing infantMain clinical findingsCase fatality rateMother-infant pairsMothers of infantsQRT-PCRZika syndromeClinical caveatsClinical findingsClinical parametersFirst trimesterCongenital alterationsLive birthsLaboratory confirmationCongenital abnormalitiesFatality rateEpidemic burstsInfectionPregnancyInfantsPrevalence, incidence and associated factors for HBV infection among male and female prisoners in Central Brazil: A multicenter study
Rezende G, Lago B, Puga M, Bandeira L, Pompilio M, Castro V, Tanaka T, Cesar G, Oliveira S, Yassuda R, Simionatto S, Weis S, Basílio S, Croda J, Motta-Castro A. Prevalence, incidence and associated factors for HBV infection among male and female prisoners in Central Brazil: A multicenter study. International Journal Of Infectious Diseases 2020, 96: 298-307. PMID: 32315810, DOI: 10.1016/j.ijid.2020.04.019.Peer-Reviewed Original ResearchConceptsHBV exposureHepatitis B virus infectionHCV/HBVIncidence of HBVHBV serological markersB virus infectionCross-sectional studyGenotypes/subtypesHBV infectionCohort studySerological markersHBV isolatesMulticenter studyHigh prevalenceLower incidenceVirus infectionHigh riskHBVNew casesBlood collectionFemale prisonersInfectionIncidencePreventive measuresPrevalenceSpirometry results after treatment for pulmonary tuberculosis: comparison between patients with and without previous lung disease: a multicenter study
Mancuzo E, Martins E, Sulmonett N, de Souza Viana V, Croda J, Kritski A, de Queiroz Mello F, de Souza Elias Nihues S, Azevedo K, de Miranda S. Spirometry results after treatment for pulmonary tuberculosis: comparison between patients with and without previous lung disease: a multicenter study. Jornal Brasileiro De Pneumologia 2020, 46: e20180198. PMID: 32130330, PMCID: PMC7462712, DOI: 10.36416/1806-3756/e20180198.Peer-Reviewed Original ResearchConceptsPrevious lung diseasePulmonary tuberculosisLung diseaseRadiological changesMulticenter studyRisk factorsLDS groupFunctional severityFunctional changesSevere radiological changesImpaired pulmonary functionRestrictive lung diseaseObstructive lung diseaseDegree of dyspneaChest X-raySpirometric changesSevere dyspneaPulmonary functionReferral centerClinical dataPatientsSpirometryDiseaseDyspneaSmoking
2019
High level of exposure to hepatitis B virus infection in a vulnerable population of a low endemic area: A challenge for vaccination coverage
Weis-Torres S, Fitts S, Cardoso W, Higa Junior M, Lima L, Bandeira L, Castro V, Carneiro F, Iglecias L, Cesar G, Tanaka T, Puga M, Rezende G, Croda J, Lago B, Motta-Castro A. High level of exposure to hepatitis B virus infection in a vulnerable population of a low endemic area: A challenge for vaccination coverage. International Journal Of Infectious Diseases 2019, 90: 46-52. PMID: 31589921, DOI: 10.1016/j.ijid.2019.09.029.Peer-Reviewed Original ResearchConceptsLow endemic areasHBV infectionHBV exposureEndemic areasHepatitis B virus infectionHIV serological markersB virus infectionHistory of surgeryHBV transmissionHBV vaccinationHBV vaccineHepatitis BChronic carriersSerological markersVaccination coverageHomosexual contactVirus infectionPrevalence ratesSusceptible adultsAge 18InfectionVulnerable populationsDisadvantaged populationsVaccinationMolecular featuresHigh Prevalence of Syphilis and Inadequate Prenatal Care in Brazilian Pregnant Women: A Cross-Sectional Study.
Benedetti K, Ribeiro A, Queiroz J, Melo A, Batista R, Delgado F, da Silva K, Croda J, Simionatto S. High Prevalence of Syphilis and Inadequate Prenatal Care in Brazilian Pregnant Women: A Cross-Sectional Study. American Journal Of Tropical Medicine And Hygiene 2019, 101: 761-766. PMID: 31407659, PMCID: PMC6779194, DOI: 10.4269/ajtmh.18-0912.Peer-Reviewed Original ResearchConceptsPregnant womenHigh prevalenceVenereal Disease Research Laboratory testDisease Research Laboratory testSeroprevalence of syphilisUnlinked anonymous testingAntenatal care servicesInadequate prenatal careRisk factor questionnaireBrazilian pregnant womenBehavioral risk factorsCross-sectional studyPresence of antibodiesTime of deliveryData of newbornsHistory of abortionAntenatal careAnonymous testingThird trimesterFirst trimesterPrenatal careSectional studyClinical managementMedical recordsRisk factorsScreening for HBV, HCV, HIV and syphilis infections among bacteriologically confirmed tuberculosis prisoners: An urgent action required
Puga M, Bandeira L, Pompilio M, de Rezende G, Soares L, de Castro V, Tanaka T, Cesar G, de Oliveira S, Teles S, Yassuda R, dos Santos Weis-Torres S, Basílio S, Croda J, Motta-Castro A. Screening for HBV, HCV, HIV and syphilis infections among bacteriologically confirmed tuberculosis prisoners: An urgent action required. PLOS ONE 2019, 14: e0221265. PMID: 31437184, PMCID: PMC6705821, DOI: 10.1371/journal.pone.0221265.Peer-Reviewed Original ResearchConceptsHepatitis B virusSyphilis infectionViral hepatitisHIV infectionB virusAnti-HCV positive samplesChronic hepatitis B virusFirst-line anti-tuberculosis drugsLifetime syphilis infectionCases of tuberculosisAnti-TB drugsCross-sectional studyPublic health problemAnti-tuberculosis drugsCurrent HCVHCV exposureHCV RNAHepatitis testingTuberculosis infectionActive syphilisSerological markersEpidemiological featuresFrequent causeSide effectsHCV
2017
High Prevalence of Treponema pallidum Infection in Brazilian Prisoners.
Correa ME, Croda J, Coimbra Motta de Castro AR, Maria do Valle Leone de Oliveira S, Pompilio MA, Omizolo de Souza R, Ferreira de Sá Queiroz JH, Esther da Silva K, Ko AI, Simionatto S. High Prevalence of Treponema pallidum Infection in Brazilian Prisoners. American Journal Of Tropical Medicine And Hygiene 2017, 97: 1078-1084. PMID: 28820706, PMCID: PMC5637599, DOI: 10.4269/ajtmh.17-0098.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBrazilCross-Sectional StudiesFemaleHumansMaleMiddle AgedPrevalencePrisonersSexually Transmitted DiseasesSyphilisTreponema pallidumConceptsActive syphilisSyphilis prevalenceHigh prevalenceBrazilian prisonersHuman immunodeficiency virus statusGenital ulcer diseaseIntravenous drug usersHigh-risk groupUnprotected sexual practicesMultivariable regression analysisCross-sectional studyActive syphilis prevalenceNew syphilis casesPopulation-based sampleDevelopment of syphilisCongenital infectionUlcer diseaseSyphilis testingRisk factorsVirus statusScreening programSerological statusSyphilis casesSevere formDrug usersResistência às drogas antituberculose na fronteira do Brasil com Paraguai e Bolívia
Marques M, Cunha E, do Socorro Nantua Evangelista M, Basta P, Marques A, Croda J, de Andrade S. Resistência às drogas antituberculose na fronteira do Brasil com Paraguai e Bolívia. BULL PAN AM HEALTH ORGAN 2017, 41: 1. PMID: 28444009, PMCID: PMC6645181, DOI: 10.26633/rpsp.2017.9.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAntitubercular AgentsBoliviaBrazilCross-Sectional StudiesFemaleHumansMaleMiddle AgedParaguayTuberculosis, Multidrug-ResistantYoung AdultConceptsObserved treatmentDrug resistanceAssociated risk factorsPulmonary tuberculosis casesHistory of alcoholismCases of PTBCombination of drugsPatterns of resistanceRespiratory symptomsPTB casesTuberculosis casesDevelopment of resistanceRisk factorsEpidemiological studiesSingle drugHealth actionsSusceptibility testingMultidrug resistanceDiabetesSusceptibility testsAlcoholismPatientsDrugsTreatmentPresence/absencePrevalence and Incidence of HCV Infection among Prisoners in Central Brazil
Puga M, Bandeira L, Pompilio M, Croda J, de Rezende G, Dorisbor L, Tanaka T, Cesar G, Teles S, Simionatto S, Novais A, Nepomuceno B, Castro L, do Lago B, Motta-Castro A. Prevalence and Incidence of HCV Infection among Prisoners in Central Brazil. PLOS ONE 2017, 12: e0169195. PMID: 28060860, PMCID: PMC5218405, DOI: 10.1371/journal.pone.0169195.Peer-Reviewed Original ResearchMeSH KeywordsAdultBrazilCohort StudiesCross-Sectional StudiesFemaleHepatitis CHumansIncidenceMaleMiddle AgedMultivariate AnalysisPrevalencePrisonersRisk FactorsYoung AdultConceptsHCV infectionCohort studyHCV RNASectional studyInjecting-drug useNew HCV infectionsHCV risk behaviorsCross-sectional studyHCV exposureHepatitis CHIV positivityEffective intervention strategiesAssociated FactorsClinical evaluationIndependent associationOverall prevalenceRisk factorsIncidence rateBlood samplesDrug useNew casesRisk behaviorsInfectionHigh frequency ratePrevalenceFrequency of indeterminate results from an interferon-gamma release assay among HIV-infected individuals
de Oliveira S, Trajman A, Paniago A, Motta-Castro A, Ruffino-Netto A, Maciel E, Croda J, da Gloria Bonecini-Almeida M. Frequency of indeterminate results from an interferon-gamma release assay among HIV-infected individuals. Jornal Brasileiro De Pneumologia 2017, 43: 215-218. PMID: 28746533, PMCID: PMC5687953, DOI: 10.1590/s1806-37562016000000125.Peer-Reviewed Original ResearchMeSH KeywordsAcquired Immunodeficiency SyndromeAdultAIDS-Related Opportunistic InfectionsBrazilCD4 Lymphocyte CountCross-Sectional StudiesFeasibility StudiesFemaleHumansInfectious Disease Incubation PeriodInterferon-gamma Release TestsLatent TuberculosisMaleMiddle AgedReproducibility of ResultsSurveys and QuestionnairesTuberculin TestConceptsInterferon-gamma releaseIndeterminate resultsHIV/AIDSIGRA resultsTuberculin skin test resultsMultivariate logistic regression modelTuberculin skin testSkin test resultsCost-effectiveness studiesLogistic regression modelsAdvanced immunosuppressionAdjusted ORsSkin testClinical variablesMedical recordsHigh prevalenceHigh riskPatientsIGRARoutine useKappa statisticsPLWHAAIDSRegression modelsKappa
2016
Epidemiological study of hepatitis B virus among prisoners with active tuberculosis in Central Brazil.
Iglecias L, Puga M, Pompílio M, Teles S, Croda J, Lima L, Lago B, Martins R, Motta-Castro A. Epidemiological study of hepatitis B virus among prisoners with active tuberculosis in Central Brazil. The International Journal Of Tuberculosis And Lung Disease 2016, 20: 1509-1515. PMID: 27776593, DOI: 10.5588/ijtld.15.0743.Peer-Reviewed Original ResearchConceptsHepatitis B virusActive tuberculosisHBV infectionB virusRisk factorsHBV surface antigen prevalenceImportant public health concernCo-infection prevalenceHBsAg-positive samplesCross-sectional studyInfection prevalence ratePublic health concernHBV DNASerological markersOverall prevalenceAntigen prevalencePrevalence ratesEffective treatmentEpidemiological studiesGenotype distributionMultivariate analysisPrison inmatesTuberculosisHealth concernInfectionFactors associated with anti-TB drug-induced hepatotoxicity and genetic polymorphisms in indigenous and non-indigenous populations in Brazil
Heinrich M, Zembrzuski V, Ota M, Sacchi F, Teixeira R, Acero P, Cunha G, Souza-Santos R, Croda J, Basta P. Factors associated with anti-TB drug-induced hepatotoxicity and genetic polymorphisms in indigenous and non-indigenous populations in Brazil. Tuberculosis 2016, 101: 15-24. PMID: 27865386, DOI: 10.1016/j.tube.2016.07.006.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAntitubercular AgentsArylamine N-AcetyltransferaseBrazilChemical and Drug Induced Liver InjuryChildChild, PreschoolCross-Sectional StudiesCytochrome P-450 CYP2E1FemaleGenetic Predisposition to DiseaseGenotypeGlutathione TransferaseHumansIncidenceInfantLongitudinal StudiesMaleMiddle AgedPolymorphism, Single NucleotideTuberculosis, PulmonaryYoung AdultConceptsIncidence of hepatotoxicityAdverse drug reactionsIndigenous patientsAnti-TB drug-induced hepatotoxicityNon-conditional logistic regressionClinical-epidemiological factorsClinical-epidemiological variablesNon-Indigenous patientsGenetic polymorphismsRisk of hepatotoxicityDrug-induced hepatotoxicityPolymorphisms of CYP2E1Anti-tuberculosis drugsAcetylation profileTB patientsSerum levelsDrug reactionsGSTM1 polymorphismOdds ratioLiver enzymesNon-Indigenous populationsTherapeutic schemesPharmacogenetic analysisBetter outcomesPatients
2015
A Cross-Sectional Survey of HIV Testing and Prevalence in Twelve Brazilian Correctional Facilities
Sgarbi RV, da Silva Santos Carbone A, Paião DS, Lemos EF, Simionatto S, Puga MA, Motta-Castro AR, Pompilio MA, Urrego J, Ko AI, Andrews JR, Croda J. A Cross-Sectional Survey of HIV Testing and Prevalence in Twelve Brazilian Correctional Facilities. PLOS ONE 2015, 10: e0139487. PMID: 26466312, PMCID: PMC4605759, DOI: 10.1371/journal.pone.0139487.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAnti-Retroviral AgentsBrazilCross-Sectional StudiesFemaleHealth Services AccessibilityHIV InfectionsHumansMaleMass ScreeningMiddle AgedMultivariate AnalysisOdds RatioPrevalencePrisonersPrisonsSurveys and QuestionnairesSyphilisVulnerable PopulationsYoung AdultConceptsHIV testingHIV careMental illnessMultivariable logistic regression modelPrevious HIV testingHIV testing ratesMajority of HIVHIV testing practicesTreatment of HIVHigh HIV prevalencePopulation-based samplePercent of participantsLogistic regression modelsAntiretroviral therapyHIV diagnosisPrevious surgeryHIV infectionHIV statusMultivariable analysisHIV prevalenceSyphilis testingClinical careGeneral populationHIVTesting ratesChronic symptoms and pulmonary dysfunction in post-tuberculosis Brazilian patients
de Sousa Elias Nihues S, Mancuzo E, Sulmonetti N, Sacchi F, de Souza Viana V, Netto E, Miranda S, Croda J. Chronic symptoms and pulmonary dysfunction in post-tuberculosis Brazilian patients. The Brazilian Journal Of Infectious Diseases 2015, 19: 492-497. PMID: 26254689, PMCID: PMC9427540, DOI: 10.1016/j.bjid.2015.06.005.Peer-Reviewed Original ResearchMeSH KeywordsAdultBrazilChronic DiseaseCross-Sectional StudiesFemaleHumansIndians, South AmericanLungMalePrevalenceRespiration DisordersSpirometryTuberculosis, PulmonaryConceptsChronic respiratory symptomsPulmonary dysfunctionRespiratory symptomsChronic symptomsObstructive disordersPost-tuberculosis patientsPrevious pulmonary diseaseCross-sectional studyPulmonary diseaseRestrictive disordersPulmonary disordersBrazilian patientsHigh prevalenceReportable diseaseFurther interventionDysfunctionSymptomsPatientsPrevalenceLifestyle differencesDisordersAORNon-Indigenous individualsYears of schoolingDiseaseSocioeconomic disadvantage increasing risk for depression among recently diagnosed HIV patients in an urban area in Brazil: cross-sectional study
Nomoto S, Longhi R, de Barros B, Croda J, Ziff E, Konkiewitz E. Socioeconomic disadvantage increasing risk for depression among recently diagnosed HIV patients in an urban area in Brazil: cross-sectional study. AIDS Care 2015, 27: 979-985. PMID: 25741909, DOI: 10.1080/09540121.2015.1017442.Peer-Reviewed Original ResearchConceptsCross-sectional studyDepressive symptomsBeck Depression InventoryHIV/AIDS patientsHIV outpatient servicesHealth-related qualityRisk of depressionLow educational levelLow incomeAntiretroviral therapyHIV patientsPoor qualityHIV infectionAIDS patientsPrevalence ratesDepression InventorySymptomsSocioeconomic disadvantageCognitive-affective factorsDepressionSocioeconomic factorsPatientsDemographic factorsPossible roleEducational levelActive and latent tuberculosis in Brazilian correctional facilities: a cross-sectional study
Carbone Ada S, Paião DS, Sgarbi RV, Lemos EF, Cazanti RF, Ota MM, Junior AL, Bampi JV, Elias VP, Simionatto S, Motta-Castro AR, Pompílio MA, de Oliveira SM, Ko AI, Andrews JR, Croda J. Active and latent tuberculosis in Brazilian correctional facilities: a cross-sectional study. BMC Infectious Diseases 2015, 15: 24. PMID: 25608746, PMCID: PMC4307675, DOI: 10.1186/s12879-015-0764-8.Peer-Reviewed Original ResearchConceptsLatent tuberculosis infectionPrevalence of LTBITuberculin skin testActive TBLTBI prevalenceWeeks of symptomsHigh transmission settingsCross-sectional studyPopulation-based samplePoisson regression modelsDuration of incarcerationHierarchical Poisson regression modelActive diseaseTB infectionLatent tuberculosisTB casesHIV testingSputum cultureTuberculosis infectionPoint prevalenceSkin testTuberculosis incidenceRisk factorsMultivariable modelSputum samples