2022
Infant BCG vaccination and risk of pulmonary and extrapulmonary tuberculosis throughout the life course: a systematic review and individual participant data meta-analysis
Martinez L, Cords O, Liu Q, Acuna-Villaorduna C, Bonnet M, Fox G, Carvalho A, Chan P, Croda J, Hill P, Lopez-Varela E, Donkor S, Fielding K, Graham S, Espinal M, Kampmann B, Reingold A, Huerga H, Villalba J, Grandjean L, Sotgiu G, Egere U, Singh S, Zhu L, Lienhardt C, Denholm J, Seddon J, Whalen C, García-Basteiro A, Triasih R, Chen C, Singh J, Huang L, Sharma S, Hannoun D, Del Corral H, Mandalakas A, Malone L, Ling D, Kritski A, Stein C, Vashishtha R, Boulahbal F, Fang C, Boom W, Netto E, Lemos A, Hesseling A, Kay A, Jones-López E, Horsburgh C, Lange C, Andrews J. Infant BCG vaccination and risk of pulmonary and extrapulmonary tuberculosis throughout the life course: a systematic review and individual participant data meta-analysis. The Lancet Global Health 2022, 10: e1307-e1316. PMID: 35961354, PMCID: PMC10406427, DOI: 10.1016/s2214-109x(22)00283-2.Peer-Reviewed Original ResearchConceptsInfant BCG vaccinationBCG vaccinationExtrapulmonary tuberculosisCohort studyIndividual participant dataPulmonary tuberculosisParticipant dataSystematic reviewIndividual-level participant dataPositive tuberculin skin testMultivariable logistic regression analysisTuberculin skin testTuberculosis infection statusParticipant-level dataLogistic regression analysisAge-specific impactStudy-level random effectWeb of ScienceIncident tuberculosisPrevious tuberculosisTuberculosis developmentSecondary outcomesTuberculosis contactsPrimary outcomeSkin test
2019
Safety and costs of blood transfusion practices in dengue cases in Brazil
Machado A, Negrão F, Croda J, de Medeiros E, dos Santos Pires M. Safety and costs of blood transfusion practices in dengue cases in Brazil. PLOS ONE 2019, 14: e0219287. PMID: 31283788, PMCID: PMC6613682, DOI: 10.1371/journal.pone.0219287.Peer-Reviewed Original ResearchConceptsHospital stayHospitalization timeHospitalisation timeWHO criteriaBlood transfusion componentsCost of hospitalisationWorld Health Organization recommendationsProspective observational studyBlood transfusion practicesPublic health problemTransfused groupBlood transfusionHospitalisation costsTransfusion practiceMedical recordsObservational studyTransfusion componentsWHO recommendationsPatientsTransfusionHealth problemsBlood componentsDengue casesStayHospitalisationPaediatric tuberculosis transmission outside the household: challenging historical paradigms to inform future public health strategies
Martinez L, Lo N, Cords O, Hill P, Khan P, Hatherill M, Mandalakas A, Kay A, Croda J, Horsburgh C, Zar H, Andrews J. Paediatric tuberculosis transmission outside the household: challenging historical paradigms to inform future public health strategies. The Lancet Respiratory Medicine 2019, 7: 544-552. PMID: 31078497, PMCID: PMC7323920, DOI: 10.1016/s2213-2600(19)30137-7.Peer-Reviewed Original ResearchConceptsM tuberculosis transmissionHousehold contact tracingTuberculosis transmissionFuture public health strategiesContact tracingGlobal tuberculosis control effortsAdult tuberculosis casesPaediatric tuberculosis infectionMycobacterium tuberculosis transmissionHigh-burden settingsTuberculosis control effortsEffective public health responsePopulation attributable fractionPublic health strategiesAge 5 yearsCommunity-based interventionsPublic health interventionsPublic health responsePediatric transmissionChildhood tuberculosisTuberculosis infectionTuberculosis casesActive surveillanceHealth strategiesHousehold exposure
2018
Assessment of Validity of a Blood-Based 3-Gene Signature Score for Progression and Diagnosis of Tuberculosis, Disease Severity, and Treatment Response
Warsinske H, Rao A, Moreira F, Santos P, Liu A, Scott M, Malherbe S, Ronacher K, Walzl G, Winter J, Sweeney T, Croda J, Andrews J, Khatri P. Assessment of Validity of a Blood-Based 3-Gene Signature Score for Progression and Diagnosis of Tuberculosis, Disease Severity, and Treatment Response. JAMA Network Open 2018, 1: e183779. PMID: 30646264, PMCID: PMC6324428, DOI: 10.1001/jamanetworkopen.2018.3779.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAntitubercular AgentsBrazilChildCohort StudiesDisease ProgressionFemaleGenes, BacterialGenetic MarkersHumansLatent TuberculosisMaleMiddle AgedMolecular TypingMycobacterium tuberculosisReal-Time Polymerase Chain ReactionReproducibility of ResultsRNA, BacterialSeverity of Illness IndexTuberculosisYoung AdultConceptsTB scoreAdolescent cohort studyNegative predictive valueTreatment responseTB diseaseCohort studyTuberculosis infectionTriage testPositron emission tomography-computed tomography scanPredictive valueLatent M tuberculosis infectionLatent Mycobacterium tuberculosis infectionPrimary health care clinicsHigh negative predictive valueCulture-positive adultsM tuberculosis infectionWhole bloodMycobacterium tuberculosis infectionEnd of treatmentHealth care clinicsCase-control studyIndependent prospective cohortsDiagnosis of tuberculosisSlower treatment responseCase-control cohortSuicide in Brazilian indigenous communities: clustering of cases in children and adolescents by household
Lazzarini TA, Gonçalves CCM, Benites WM, da Silva L, Tsuha DH, Ko AI, Rohrbaugh R, Andrews JR, Croda J. Suicide in Brazilian indigenous communities: clustering of cases in children and adolescents by household. Revista De Saúde Pública 2018, 52: 56. PMID: 29791676, PMCID: PMC5958965, DOI: 10.11606/s1518-8787.2018052000541.Peer-Reviewed Original ResearchConceptsHealth interventionsSuicide ratesHousehold clustersRetrospective cohort studyBroader public health interventionsConclusions High ratesPublic health interventionsMental health interventionsHigh rateCohort studyHigh suicide ratesLower socioeconomic indicatorsAdult suicideAdolescent malesOverall suicide ratesChildrenSuicideGreater proportionChild suicideInterventionSocioeconomic indicatorsAdolescentsIndigenous individualsSuicide clustering
2017
Seroprevalence of Chikungunya Virus in a Rural Community in Brazil
Cunha R, Trinta K, Montalbano C, Sucupira M, de Lima M, Marques E, Romanholi I, Croda J. Seroprevalence of Chikungunya Virus in a Rural Community in Brazil. PLOS Neglected Tropical Diseases 2017, 11: e0005319. PMID: 28107342, PMCID: PMC5287455, DOI: 10.1371/journal.pntd.0005319.Peer-Reviewed Original ResearchConceptsCases of chikungunyaCHIKV infectionChikungunya virusCHIKV IgMSymptomatic CHIKV infectionIgM-specific antibodiesFeira de SantanaIgG-specific antibodiesEpidemiological surveillance systemBrazilian Epidemiological Surveillance SystemCHIKV IgGModerate seroprevalenceSeropositive patientsJoint painIgG antibodiesCHIKV transmissionFirst serosurveySeroprevalenceInfectionMagnitude of transmissionAntibodiesPatientsFirst caseSerosurveyIgM
2016
Factors associated with anti-TB drug-induced hepatotoxicity and genetic polymorphisms in indigenous and non-indigenous populations in Brazil
Heinrich M, Zembrzuski V, Ota M, Sacchi F, Teixeira R, Acero P, Cunha G, Souza-Santos R, Croda J, Basta P. Factors associated with anti-TB drug-induced hepatotoxicity and genetic polymorphisms in indigenous and non-indigenous populations in Brazil. Tuberculosis 2016, 101: 15-24. PMID: 27865386, DOI: 10.1016/j.tube.2016.07.006.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAntitubercular AgentsArylamine N-AcetyltransferaseBrazilChemical and Drug Induced Liver InjuryChildChild, PreschoolCross-Sectional StudiesCytochrome P-450 CYP2E1FemaleGenetic Predisposition to DiseaseGenotypeGlutathione TransferaseHumansIncidenceInfantLongitudinal StudiesMaleMiddle AgedPolymorphism, Single NucleotideTuberculosis, PulmonaryYoung AdultConceptsIncidence of hepatotoxicityAdverse drug reactionsIndigenous patientsAnti-TB drug-induced hepatotoxicityNon-conditional logistic regressionClinical-epidemiological factorsClinical-epidemiological variablesNon-Indigenous patientsGenetic polymorphismsRisk of hepatotoxicityDrug-induced hepatotoxicityPolymorphisms of CYP2E1Anti-tuberculosis drugsAcetylation profileTB patientsSerum levelsDrug reactionsGSTM1 polymorphismOdds ratioLiver enzymesNon-Indigenous populationsTherapeutic schemesPharmacogenetic analysisBetter outcomesPatients
2014
Health-service performance of TB treatment for indigenous and non-indigenous populations in Brazil: a cross-sectional study
Lemos E, Alves A, Oliveira G, Rodrigues M, Martins N, Croda J. Health-service performance of TB treatment for indigenous and non-indigenous populations in Brazil: a cross-sectional study. BMC Health Services Research 2014, 14: 237. PMID: 24885134, PMCID: PMC4049501, DOI: 10.1186/1472-6963-14-237.Peer-Reviewed Original ResearchConceptsNon-Indigenous populationsTB diagnosisPrimary Care Assessment ToolNon-Indigenous patientsCare Assessment ToolCross-sectional studyHealth service performanceTB patientsMost patientsSymptom onsetTB careTB treatmentTuberculosis controlTreatment strategiesMedical appointmentsHome visitsFirst treatmentHealth professionalsHealth servicesPatientsDiagnosisHealthcare qualityTreatmentSocial supportAssessment tool
2013
Impact of Latent Infection Treatment in Indigenous Populations
Yuhara L, Sacchi F, Croda J. Impact of Latent Infection Treatment in Indigenous Populations. PLOS ONE 2013, 8: e71201. PMID: 23936264, PMCID: PMC3729554, DOI: 10.1371/journal.pone.0071201.Peer-Reviewed Original ResearchConceptsSmear-positive index casesTuberculin skin testActive tuberculosisLatent infectionIndex caseInfection treatmentLatent tuberculosisActive diseaseTuberculosis contactsRetrospective studySkin testClinical recordsRisk factorsNotification databaseMultidisciplinary teamClose contactTuberculosisInfectionTreatmentAgeEstimated numberPresent studyMorbidityIndigenous BraziliansCasesEvaluation of the traditional and revised world health organization classifications of dengue cases in Brazil
Lima F, Croda M, Muniz D, Gomes I, de Moraes Soares K, Cardoso M, Tauro R, Croda J. Evaluation of the traditional and revised world health organization classifications of dengue cases in Brazil. Clinics 2013, 68: 1299-1304. PMID: 24212835, PMCID: PMC3798712, DOI: 10.6061/clinics/2013(10)02.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge DistributionAgedAged, 80 and overBrazilChildChild, PreschoolCross-Sectional StudiesDengueFemaleHospitalizationHospitals, UniversityHumansInfantIntensive Care UnitsMaleMedical RecordsMiddle AgedSeverity of Illness IndexSex DistributionWorld Health OrganizationYoung AdultConceptsCross-sectional studySevere dengueDengue feverRevised classification systemWorld Health Organization classificationWorldwide public health problemDengue hemorrhagic shockRisk of progressionRisk of complicationsDistribution of patientsDengue hemorrhagic feverPublic health problemWarning signsClassification systemWorld Health OrganizationClinical suspicionHemorrhagic shockOrganization classificationUniversity HospitalMedical recordsSevere diseaseHemorrhagic feverSevere casesPatientsClinical practice
2008
Potential immunomodulatory effects of plant lectins in Schistosoma mansoni infection
Reis EA, Athanazio DA, Cavada BS, Teixeira EH, de Paulo Teixeira Pinto V, Carmo TM, Reis A, Trocolli G, Croda J, Harn D, Barral-Netto M, Reis MG. Potential immunomodulatory effects of plant lectins in Schistosoma mansoni infection. Acta Tropica 2008, 108: 160-165. PMID: 18579103, DOI: 10.1016/j.actatropica.2008.05.025.Peer-Reviewed Original ResearchConceptsPatients' peripheral blood mononuclear cellsPeripheral blood mononuclear cellsCytokine productionElevated IL-5 productionTh2-like cytokine responseIL-5 productionSchistosoma mansoni infectionStimulation ex vivoTh2-like responseBlood mononuclear cellsPotential immunomodulatory effectsSoluble egg antigenExperimental murine modelTh2 environmentPBMC supernatantsIL-10Mansoni infectionCytokine responsesEgg antigenImmunomodulatory effectsMononuclear cellsInfected patientsIL-5TNF-alphaLymphocyte stimulator